In this, the drugs are not manufactured by the owner company but are manufactured by another company.

The manufacturer company holds global licenses.

It ensures quality and regulatory compliance.

The owner holds the right to sell and market the products.

What is a Contract Development and Manufacturing Organization (CDMO)?

It is the manufacturing process from drug discovery to finished dosage formulation.

It involves a rigorous research and drug development process.

It includes the clinical trial process/ complete drug design.

The benefits of contract pharmaceutical manufacturing for global exporters- 

Contract manufacturing helps global exporters save the cost of production.

• Eliminates the need for heavy investments
• It reduces regulatory burdens
• It leads to faster market access.
• Scalable production

How to select the best pharmaceutical contract manufacturer?

Making informed decisions fixes the need and alleviates unnecessary uncertainties.

Manufacturing Infrastructure- 

The manufacturer must implement advanced manufacturing processes.

• In-house laboratories
• Advanced instruments
• Automated systems
• Sterility and containment facilities
• Qualified utilities

Regulatory compliance- 

The exporters must ensure the regulatory-compliant manufacturing facilities.

The manufacturing unit must be WHO-GMP and ISO compliant.

For marketing products in strict markets, the manufacturers must hold country-specific regulatory certifications.

Quality Assurance – 

The manufacturer must ensure strict regulatory adherence.

They must be able to provide-

• Batch analysis certificates
• Real-time stability testing data
• Ensure batch consistency
• Raw material quality

Manufacturing capabilities /capacity – 

The dedicated facilities for toxic drug manufacturing.

Sterility and containment procedures.

The company must be able to manufacture advanced dosage formulations.

Sterile injectables, orals, and solid dosage forms.

Understand the capacity or the volume of manufacturing.

Confidentiality – 

The manufacturing company must protect the proprietary rights of the owner company.

It must preserve the formula and the brand rights of the company.

Supply chain Efficiency – 

• Proper logistic management
• Traceable supply chain
• Integrated cold chain

Transparency – 

The manufacturer must manage transparency at all manufacturing steps.

From procuring raw material, raw material quality, and finished product quality, the supply chain must be transparent and documented.

Affordability without compromising quality – 

The manufacturer must balance affordability and quality.

Global standard products must be manufactured without compromising quality.

Implementing new technology and automated processes maintains quality and also minimizes wastage.

Which is the globally recognized pharmaceutical contract manufacturer from India?

Aprazer Healthcare is a renowned pharmaceutical contract manufacturer from India.

We are built on a long-standing reputation of zero non-compliant audit history.

Our manufacturing unit adheres to WHO-GMP /EU-GMP standards.

Leveraging advanced technology, we are capable of manufacturing a comprehensive drug class.

Our extensive product portfolio spans –

• Oncology medicines 
• Hepatitis B Medicines 
• Hepatitis C Medicines 
• HIV medicines

Our core values that make us the leaders in contract drug manufacturing-

• Cost transparency
• Global compliance
• Fair MOQs
• Consistent quality
• Robust costumer services
• Regulatory expertise

Tranexamic acid is a synthetic derivative.

It stops the excessive bleeding.

It prevents the dissolution of the blood clot.

It is an antifibrinolytic agent.

What is Tranexamic Acid (TXA) tablet used for?

It is widely used in surgical and medical conditions.

It inhibits the breakdown of the clot.

It prevents blood loss during –

• Heavy menstrual /postpartum bleeding
• Blood loss during surgery /trauma
• Dental procedures
• Nose bleeds

Tranexamic acid working –

It inhibits the plasmin enzyme.

Plasmin helps dissolve the clots.

Blocking the enzyme promotes clot formation.

It slows down bleeding.

Clot formation prevents blood loss.

Tranexamic acid use in trauma /surgery- 

Tranexamic acid is widely used in trauma or hemorrhage.

It inhibits clot breakdown. It stops excessive bleeding.

It is given intravenously during accidents or traumatic hemorrhage.

It minimizes postoperative and intraoperative blood loss.

It is applied topically at the surgical site.

It helps reduce bruising and swelling.

The role of Tranexamic acid in period management (Menorrhagia)- 

It is widely prescribed to manage heavy bleeding.

It slows down the breakdown of the clots.

It prevents excessive blood loss.

It is a non-hormone treatment.

It does not alter the hormones or the menstrual cycle.

Tranexamic acid use for skin issues- 

Topical Tranexamic acid is widely applied to harness its anti-inflammatory properties.

Tranexamic acid blocks the pathway of pigmentation.

It is widely used to treat –

• Skin pigmentation
• Melasma
• Skin discoloration

It brightens the skin.

It minimizes dark sunspots/age spots on the skin.

Does tranexamic acid tablet relieve pain during periods?

Tranexamic acid does not help manage pain during periods.

It just prevents heavy bleeding and blood loss.

Tranexamic acid side effects – 

The common side effects include-

• Headache
• Nasal congestion
• Muscle pain, joint pain
• Nausea
• Diarrhea
• Severe weakness

Serious side effects – 

• Blood clot in the lungs, arms, etc.
• Trouble breathing
• Blurred vision
• Severe allergic rashes
• Stroke /heart issue

The third-party pharmaceutical manufacturer – A global export partner 

Aprazer Healthcare is a pharmaceutical manufacturing company.

We manufacture a diverse range of life-saving medicines.

We are a trusted third-party drug manufacturer and exporter.

Our product portfolio includes-

• Anticoagulants & Anti-fibrinolytic
• Antispasmodic Combination

We are a leading pharmaceutical company trusted by global exporters.

We export high-quality products to countries in Asia, Africa, and America.

Aprazer Healthcare manufactures a comprehensive range of anti-infective drugs.

Leveraging modern infrastructure, Aprazer Healthcare specializes in manufacturing complex dosage formulations.

We manufacture specialized dosage forms including all types of tablets and capsules.

Our extensive anti-infective product portfolio includes-

• Antibiotic combinations 
• Antifungal drugs 
• Antiviral drugs 
• Anthelmintic drugs

Our flagship products include-

• Apraketo – Ketoconazole tablets
• Azithrokast 500– Azithromycin 500mg
• Ciprokast 500 – Ciprofloxacin 500mg
• Zerquan – Praziquantel

Manufacturing a complete range of antiviral drugs, Aprazer Healthcare is the leading manufacturer of –

• Antiretroviral combinations for HIV.
• Hepatitis B antivirals
• DDAs for Hepatitis C

Aprazer Healthcare is the leading contract drug manufacturing organization for anti-infective drugs. Why?

Regulatory compliance – 

WHO-GMP and EU-GMP certified manufacturing units.

We have a long track record of manufacturing global quality drugs.

Our regulatory expertise, easily navigate export challenges.

Quality Assurance –

Adherence to regulatory standards, maintaining sterility and precision.

• Advanced air-handling systems
• Separate blocks for beta-lactam antibiotics.
• Environmental controls
• Uniformity of content
• Precise dose formulations
• In-house quality checks
• Pharmaco-vigilance and data integration.

Robust distribution network- 

Aprazer Healthcare is the top supplier of anti-infective drugs in America, Africa, and Asia.

From procuring raw material to end-mile distribution, we have a transparent supply chain.

• Authentic supply logistics
• Cold chain supply

Extensive product portfolio – our widest portfolio includes all antibiotics and antivirals.

Crisis resilience – we remain crisis-ready in manufacturing large-scale anti-infective during an epidemic.

Scalable production – we are capable of manufacturing large-scale and small-scale batches. 

Cost–effective manufacturing – Leveraging advanced technology and automated systems, we focus on preventing wastage and lowering production costs.

Why is precision required in manufacturing anti-infective drugs?

Unlike other generic formulations, anti-infective drugs need precise doses.

These directly target the viable microbes.

Any fluctuation in dosage may lead to failure of treatment.

The low doses may not achieve the required efficacy.

Higher doses may lead to toxicity.

It also increases the risk of antimicrobial drug resistance.

Why complete a full course of antibiotic drugs?

Leaving the antibiotic course in the middle may lead to re-infection.

An incomplete course may not be effective in killing the complete bacterial count.

It also leads to drug resistance; the microbes mutate and may not respond to the same drug.

Why trust Aprazer Healthcare?

Aprazer Healthcare is a trusted contract pharmaceutical manufacturer.

Our core values of transparency/streamlined work processes define us as a trusted CMO from India for global brands.

Partner with Aprazer Healthcare-secure your effective drug supplies.

Thalassemia is an inherited blood disorder.

It occurs at birth. The condition is misdiagnosed as jaundice or any other disorder.

Without proper treatment in childhood, it significantly retards growth.

Treatment during the early years can reduce lifelong complications.

At Aprazer Healthcare (pharmaceutical manufacturer), we believe genetic disorders managed or treated promptly can prevent long –term complications.

Recognizing the symptoms at the earliest eases management enhance cure.

As the leading drug manufacturer, we are focused on developing advanced treatment drugs for chronic disorders.

With our strong global presence, we are a leading drug distributor to major countries.

The forms of Thalassemia –

Mild Thalassemia: It occurs without symptoms, causing mild anemia.

It mimics iron deficiency.

Individuals are prescribed unnecessary iron supplements.

The person does not require any specific treatment.

Moderate Thalassemia-

It is usually diagnosed in adulthood or late childhood.

It is mistaken for chronic weakness.

Untreated thalassemia leads to the formation of gallstones.

Chronic leg ulcers and iron buildup in the organs.

Severe Thalassemia –

In a severe condition, symptoms appear in the first 6 to 24 months.

It inhibits the growth of children.

It distorts the physical structure.

It leads to enlarged organs.

Heart and liver failure.

What are the early symptoms of thalassemia to be traced?

The early symptoms appear at 3 to 6 months of age.

The symptoms become highly pronounced by the age of 2.

• Pale skin, lips, and palms
• Avoidance of taking a feed
• Mild jaundice
• Weak child
• Dark urine
• Abdominal swelling

Symptoms in adulthood-

• Chronic fatigue
• Slow growth
• Delayed puberty
• Frequent infections

How to treat Thalassemia?

Minor thalassemia –

No major surgery or intervention is required.

A person can live a healthy, complication-free life.

It causes mild, borderline anemia.

Symptom monitoring and various wellness strategies are effective to prevent any complications.

Major thalassemia –

It requires surgery like a bone marrow transplant, splenectomy, etc.

Regular blood transfusions are required in moderate to major disease.

Iron supplements are not recommended in thalassemia. Why?

Blood cells in thalassemia mimic iron deficiency.

The blood cells formed are small and very few.

It is caused by the genetic deformity.

Taking iron supplements increases the iron load in the body.

Excess iron damages build up in the organs.

It severely affects the heart, liver, and endocrine glands.

Lifestyle and Dietary support to manage thalassemia-

Avoid unnecessary iron supplements-

It can damage the organs.

Iron supplements must be taken after identifying the exact iron deficiency.

They must be taken upon a doctor’s prescription.

Folic supplements-

It helps build healthy blood cells in the bone marrow.

Proper diet-

Avoid high iron rich diet.

Use vitamin C and calcium-rich foods.

Avoid infections and illnesses –

Severe illness can stress out the bone marrow.

It can sharply reduce hemoglobin levels.

Importance of proper reproductive care and family planning –

The parents must be screened for thalassemia.

A recessive trait in both the parents increases the risk of developing major thalassemia in the newborn.

If one parent has a recessive gene, it is likely the newborn will develop mild conditions.

Alternative pregnancy methods may be utilized.

Aprazer Healthcare is focused on defeating chronic health conditions through timely intervention and treatment.

These require stringent quality controls and regulatory adherence.

Chemotherapy is usually given in the form of injectables or infusions.

What are sterile injectables?

Sterile injectables are drugs administered by injection.

They are sterile preparations, free from pyrogen or any other microorganism.

It includes –

• Intravenous injections
• IV infusions
• Intramuscular injection
• Subcutaneous injection

The need for sterility in Injectables- 

The drugs are directly administered into the bloodstream.

They have rapid effects. These bypass the first-pass metabolism.

Any contamination may directly lead to severe health risks.

What are the benefits of injectables?

• These bypass the GIT.
• 100 percent bioavailability
• Rapid action
• No GIT side effects

What is the sterile manufacturing process for oncology injectables? 

• Aseptic manufacturing – 

The drugs are mixed or processed in sterile closed-loop conditions.

• Sterile raw material
• Pyrogen-free water
• Environmental controls
• Containment control

 Personnel safety – 

The working people must be protected from cytotoxic agents.

• Use protective gear and clothing.
• Air lock-lock systems
• Access restrictions

• Sterilization and filtration – 

The products are filtered to remove particulate matter.

The glass vials are washed and depyrogenated.

Rubber stoppers are sterilized.

• Aseptic fill finish /lyophilisation- 

The sterile liquid preparations are dispensed in sterile vials or containers in an aseptic chamber.

The injectable flow is unidirectional.

The filling process should be free from any contamination.

The heat-sensitive oncology drugs are half-stoppered in the vials.

These are transferred to freeze–dryers to remove water.

The aluminum seals are crimped onto the vials immediately removing from the freeze dryers.

The sealing must be done in protected air zones to prevent contamination.

• Quality control and inspection – 

The vials are inspected for leaks or particulate matter.

Container closure integrity.

Sterility testing/bacterial endotoxin testing.

WHO – GMP Regulations for sterile injectable manufacturing 

The GMP standards emphasized:

• Product quality
• Sterility control
• Manufacturing consistency
• Regulatory compliance

EU-GMP regulations for sterile injectable manufacturing 

EU-GMP practices emphasize-

• Cleanroom classification
• Personnel controls
  • Contamination prevention
  • Environment monitoring
  • Air barriers

Why choose Aprazer Healthcare for oncology injectables?

Aprazer Healthcare is the leading oncology injectable manufacturer.

We are global oncology drug exporters.

We are equipped with world-class infrastructure.

We are accepted and trusted due to our quality attributes-

• Global Manufacturing standards
• Rigorous quality controls
• Regulatory compliance
• Containment prevention
• Cost-efficient manufacturing

It consists of the international /universal standards of product quality /safety.

It is the basic requirement for all manufacturers to implement GMP.

EU-GMP focuses on essential GMP controls along with country-specific regulations.

This includes additional regional regulatory qualifications.

WHO-GMP manufacturing – 

It is the global authority that forms the backbone of the regulatory framework.

The core principles remain consistent across the globe.

It is a basic requirement that ensures product safety and quality.

The GMP goals include –

• Safeguards patient safety
• Ensures product quality
• It forms the base of regulatory approvals
• Reduces the risk of product recall.

EU-GMP manufacturing – 

It is European Union Good Manufacturing Practices.

This includes the specifications for the sale of drugs in Europe.

Along with the basic GMP principles, EU-GMP includes variations in regulatory frameworks.

It is the difference in methodology –

• Variation in audits
• Documentation structure
• Quality systems

What are WHO-GMP regulations?

The GMP guidelines ensure consistent product quality in accordance with the intended use.

It includes-

• Process of manufacturing
• Raw material
• Training facilities
• Documentation
• Distribution

What are EU-GMP regulations?

These regulations apply to manufacturers, exporters, and distributors.

These are mandatory requirements for the sale of medicines in Europe.

These lay strong emphasis on –

• Pharmaceutical quality systems
• Risk management
• Documentation /traceability
• Trained professionals

Is the WHO-GMP standard of manufacturing enough for global export?

WHO-GMP is applicable in many countries.

However, the highly regulated market requires additional inspections and approvals.

The countries where only WHO-GMP is eligible – 

It is highly beneficial for low-income countries, ensuring product quality.

It is acceptable in countries in Africa, the Middle East, and parts of Asia.

It also forms the basis of drug qualification by the UN and International health agencies.

The countries that require additional approvals – 

The additional regulatory frameworks are required in –

UK, USA, and European markets.

These are the stringent markets.

They individually assess the manufacturing facilities.

They enforce distinct local documentation based on the region.

Which is the WHO-GMP /EU-GMP certified pharmaceutical manufacturer?

Aprazer Healthcare is the leading pharmaceutical company from India.

It specializes in manufacturing GMP-compliant drugs.

We are the leading drug supplier to the international market.

Our regulatory team has expertise in drug approvals in different targeted markets, technical standards, and documentation demands.

Implementing cutting–edge technical flow, our manufacturing units are compliant with EU regulatory norms, providing complete documentation and regulatory support.

Our fully automated systems hold a zero-tolerance stance on data gaps, favoring EU-GMP steep technological requirements.

WHO establishes stringent parameters for manufacturing oncology medicines.

The anti-cancer drugs are highly toxic, potent medicines.

They are developed in controlled environments with safety parameters.

Facility design/containment systems – 

Dedicated facilities- 

These are separate blocks or rooms for manufacturing toxic drugs.

Dedicated blocks for multi-step processes like granulation, blending, and tableting.

• Segregated material flow
• Restricted access barrier system
• Air-lock systems between multi-chamber rooms.
• Air-tight architecture, sealed floors and roof

Air conditioning systems (HVAC) – 

It is used for clean room standardization and environmental isolation.

• Maintaining pressure variants in toxic zones.
• HEPA filters for air filtration.
• Unidirectional airflow
• Temperature and humidity control

 Personnel Safety – 

The anticancer drugs are highly toxic and irreversibly damage living tissue.

The manufacturers must ensure high safety measures for the workers.

Cytotoxic drug handling training must be provided.

• Use of protective gear /garments
• Air borne drug /particulate matter monitoring.
• Decontamination facilities like dedicated shower or eye wash stations.

Validation process- 

It ensures that each activity and process is under permissible limits.

• Equipment /instrument validation
• Operational validation
• Design validation
• Installation validation
• Performance validation
• Cleaning validation

Waste product management – 

The residue of the oncology drugs is highly toxic.

WHO recommends safe disposal of toxic components.

• Separate in/out bags.
• Chemical treating systems
• Segregation for biological, hazardous, or general waste
• Fumigation exhausts to neutralize toxic vapors.

Why is a stringent regulatory framework required for oncology drug manufacturing?

The manufacturing process of oncology drugs demands high precision and sterility.

These are cytotoxic drugs.

These are lethal and directly kill viable cells.

Requirement for precision- 

They have narrow safety margins.

Large doses damage the organs.

A lowered dose may lead to treatment failure.

Safety of personnel- 

Spilling or touching the drug component may damage human cells.

It can cause serious complications.

Dedicated flow lines- 

This prevents cross-contamination.

A trace of the cytotoxic drug clinging to the pipes may get incorporated into other medicines through the same pipeline.

The Air flow systems- 

Any vapor or fumes of the toxic product in the air may lead to hazardous results when inhaled.

The particulate matter in the air may contaminate other general products.

Which is the leading WHO-GMP certified oncology medicine manufacturer? 

Aprazer Healthcare is an oncology medicine manufacturer.

Globally recognized for manufacturing top quality pharmaceuticals, we are the leading oncology drug exporters.

We are trusted for our commitment to quality (WHO-GMP standards).

We manufacture a wide range of oncology drugs.

Oncology orals/Oncology injectable

Our flagship products include chemotherapy injectables-

• Carboplatin – Carbokast 150 
• Cisplatin – Cycokast -50 
• Cytarabine 500mg – Cytarzer 500 
• Doxorubicin – Dorucin -10 

It contributes to 22 % of the total supply of generic hepatitis medicines.

Despite the major supply, Hepatitis remains a global health crisis.

Global Burden and Treatment Gap 

• More than 350 million people worldwide suffer from hepatitis infection.
• 1.3 million Deaths occur every year due to the severe lack of testing and treatment access.
• 1.1 million Deaths occur due to cirrhosis caused by untreated Hepatitis B.
• Fewer than 5 % of infected individuals receive the life-saving antiviral treatment.

The common hepatitis drugs exported from India

Hepatitis C medicines exported from India – 

Sofosbuvir + Velpatasvir tablets – Velakast

Daclatasvir and Sofosbuvir Tablets – Sofokast Plus

Ledipasvir & Sofosbuvir Tablets- Ledikast

Daclatasvir Tablets- Dacikast

Ribavirin Capsules- Ribasure

Sofosbuvir Tablets – Sofokast

Hepatitis B medicines exported from India – 

Tenofovir Alafenamide 25 mg tablet- Tafnext

Entecavir 1mg- Entekor-1

Tenofovir Disoproxil Fumarate Tablets- Tudobest

Why Aprazer Healthcare is the leading Hepatitis Medicine Manufacturer/exporter 

World-class infrastructure- 

Equipped with modern equipment and technology, we are capable of manufacturing advanced products.

The advanced manufacturing processes minimize wastage, leading to cost-effective manufacturing.

Regulatory compliance 

Our manufacturing processes strictly adhere to WHO-GMP /EU-GMP regulations.

Robust Quality controls 

We adhere to the global standards of manufacturing.

• Stringent quality control protocols
• In–house quality checks and controls
• In-house testing

Strong distribution network 

We are globally present, supplying affordable standard-quality drugs.

• Cold chain delivery systems
• Traceable supply chain
• Authentic logistic support

Robust documentation support

Our team of experts offers end-to-end support in –

• Drug approvals
• CTD dossiers for pharmaceutical importers
• Custom and logistic documents

Extensive product portfolio – 

We specialize in manufacturing antiviral combinations

Our product portfolio comprises a comprehensive range of –

• Hepatitis B medicines
• Hepatitis C medicines

Why is it important to treat Hepatitis timely? 

The delayed /untreated hepatitis infection progresses to irreversible liver damage.

• It leads to liver scarring.
• increases the risk of liver cancer
• Increases the risk of spreading the virus

Which hepatitis infection is curable?

Hepatitis C is highly curable.

It is treated by direct-acting antivirals.

Hepatitis B is not curable.

It is managed and treated by antiviral combinations.

How do hepatitis medicines work? 

Hepatitis C medicines target the proteins required for viral cell multiplication.

It stops cell multiplication, leading to elimination.

Hepatitis B suppresses the virus. It lowers the viral count.

It prevents liver scarring and improves immunity.

What are the hepatitis medicine side effects?

The common side effects include-

• Weakness
• Dizziness
• Headache
• Stomach ache
• Diarrhea
• Insomnia

Treat the lethal virus through the effective solution offered by Aprazer Healthcare. 

Aprazer Healthcare, as the leading ( Hepatology medicine manufacturer) is the trusted hepatitis medicine exporter.

We are the top drug exporters to countries in

Asia, Africa, the Middle East, and America.

Cholesterol is a waxy or fatty fluid in the body.

It is widely utilized to make vitamins and hormones.

• Forms the outer cell wall layer
• Forms hormones like estrogen and testosterone
• Aids digestion
• Protects nerve fibers

The main types of cholesterol- 

• HDL – These are high-density lipoproteins.

It is also called good cholesterol.

It is the clearance of extra cholesterol from the body.

The excess cholesterol is carried in the blood to the liver.

The higher levels indicate the body is clearing lipids.

• LDL: It is also called bad cholesterol.

These are low-density lipoproteins.

This indicates the blood is unable to carry extra cholesterol.

The lipids build up in the arteries.

It increases the risk of heart disease.

• Triglycerides – These are the fat cells in the body.

These store extra energy when the body is unable to burn calories.

The extra calories are stored in the form of triglycerides.

The normal cholesterol ranges- 

• Total cholesterol – Less than 200mg/dl

• LDL – Less than 100mg /dl
• HDL- It must be 60mg/dl or higher
• Triglycerides – It must be less than 150mg/dl

What symptoms must one look for in high cholesterol?

It does not show any physical signs.

The rare symptoms include-

• Yellow patches around the eyes
• Fatty bumps or growths on the skin
• Cholesterol deposition around the iris in the eye.

In the long term, it leads to –

• Chest pain
• Shortness of breath
• Leg pain

Why is HDL good cholesterol? 

HDLs are protective cholesterol.

It eliminates the extra cholesterol from the body.

It carries it to the liver for breakdown.

It is protective in nature.

It prevents blockages in the arteries or heart.

What is the negative effect of cholesterol on the heart? 

Cholesterol harms the body in several ways.

The lipids deposit in the arteries.

It increases the risk of –

• Heart diseases
• Stroke
• Arthrosclerosis

The causes of high cholesterol- 

• High-fat diet
• Family history
• Inactivity
• Chronic stress
• Excessive alcohol /smoking
• Genetics
• Age /sex

The cholesterol-lowering drugs- 

• Statins – This reduces the synthesis of cholesterol in the liver.

Atorvastatin, Rosuvastatin

• Cholesterol absorption inhibitors – 

These inhibit cholesterol absorption in the stomach.

• Bile Acid Sequestrants- These agents bind to cholesterol.

It helps utilize body cholesterol.

• Fibrates- These lower the triglyceride levels.

• PCSK9 Inhibitors- 

These drugs block the proteins that destroy LDL receptors.

The LDL receptors are preserved.

They carry more lipoproteins to the liver.

This leads to clearing more cholesterol from the blood.

Can I lower high cholesterol?

Managing an active lifestyle with proper medication.

• Low-fat diet
• Regular exercise
• Proper medication

Who all must take cholesterol medication?

The cholesterol medicines are prescribed based on future cardiac risks.

Cholesterol drugs are usually given to people with –

• Cardiac disorders
• Extremely high LDL levels
• People with diabetes
• High risk of heart disease in the upcoming 10 years.
• High Blood pressure
• Dangerously high cholesterol
• Family history

Which is the leading third-party lipid-lowering drug manufacturer?

Aprazer Healthcare is a leading third-party manufacturer.

We manufacture a global range of cardiovascular drugs.

Our product portfolio includes –

• Lipid-lowering agents 
• Antihypertensive combinations
• Antilipemic Agents Combination & HMG-CoA Reductase Inhibitors (Statins)

Supplying drugs globally, we are the top drug distributors.

• Global standard manufacturing
• Regulatory compliance
• Robust quality controls
• Strong distribution network
• Trusted partnerships

These are involuntary muscle contractions.

They cause rapid, uncontrolled movements in the body.

Convulsions are common in epilepsy.

The causes of convulsions include –

• Epileptic seizures – Due to changes in electrical signals in the brain.

• Non-epileptic seizures –  These are caused due to psychological illness
• Febrile seizures – These occur in children having high fever.

The common illness with recurrent convulsions- 

Epilepsy: causes and symptoms 

It is a brain dysfunction.

It happens due to abnormal electrical signals in the brain.

It is the recurrence of seizures.

The different types of seizures- 

• Focal seizures- 

When the seizure affects one side of the brain.

• Generalized seizures- 

When the seizure occurs on both sides of the brain.

The common symptoms of Epilepsy- 

• Rigid muscles
• Leg jerking
• Starring spell
• Loss of muscle control
• Repetitive movements
• Loss of bladder functions
• Loss of awareness
• short-term confusion

The causes of epilepsy- 

The abnormal conduction in the brain may lead to twitching or seizures.

The causes include-

• Structural changes in the brain – Any changes in the brain anatomy.

Head injury, trauma, strokes, or tumors.

• Family history /genetics – History of seizures in close relatives and genetics.
• Brain infections- infections like meningitis or abscess in the brain.
• Metabolic dysfunction –Fluctuating sugar or changes in neurotransmitter levels.
• Autoimmune disorders – Like ADHD, autism, etc.

The factors that trigger seizures- 

• Lack of sleep
• Alcohol
• Smoke
• Illicit drug use
• Stress
• Dehydration
• Skipped meals

What are the anti-epileptic drugs?

Sodium channel blockers – Phenytoin, carbamazepine

It inhibits rapid nerve conduction.

It blocks sodium entry.

GABA boosters – clonazepam, lorazepam

GABA is a neurotransmitter that calms nerve activity.

It reduces the rapid nerve firing.

Calcium channel blockers- Ethosuximide

It blocks the calcium channel.

It reduces nerve firing.

GABA/Glutamate modulators- 

These drugs balance the excitatory and the inhibitory chemicals in the brain.

Why is it advised to strictly adhere to anti-epileptic treatment?

It is advised to consistently take epilepsy medicines upon time.

Leaving or altering the dose may cause complications.

• Triggers seizures
• Prolong the length of seizures
• Uncontrolled seizures

What are the side effects of anti-epileptic drugs?

• Sleepiness
• Tiredness
• Stomach upset
• Blurry vision
• Unexpected weight
• Brain fog
• Mood shifts

Severe side effects –

• Severe skin rashes
• Yellowish skin
• Stomach ache
• Unusual bleeding /bruising
• Severe depression

Which is the third-party drug manufacturer of anticonvulsant?

Aprazer Healthcare is the leading pharmaceutical manufacturer.

We manufacture and export a global range of anti-epileptic combinations worldwide.

Accredited and licensed by the global health authorities, our products are trusted and demanded.

We are chosen for our credibility, such as:

• Operational excellence
• Regulatory compliance
• Precision manufacturing
• Advanced infrastructure