Childhood cancers are increasingly on the rise. The delay in diagnosis is the major reason.

The different types of cancers in children include –

• Blood cancer

• Bone cancer

• Spinal cord cancer

• Other tumors

Chemotherapy forms an essential part of the treatment.

It is highly effective and has better outcomes.

Children can tolerate strong and intensive chemotherapy cycles.

They show faster recovery, which significantly increases the chances of cancer remission and longer survival.

What is Childhood Cancer?

The cancers that occur at a young age.

• Pediatric cancer (0-14 years)

• Adolescent cancer (15 -19 years)

The Difference Between Childhood Cancers From Adult Cancers

It is different from adult cancers.

Adult cancers can be caused by lifestyle or other environmental factors.

Childhood cancers have a genetic origin or some other biological factors.

These cancers are often treatable at the early stages.

What is leukemia?

It is a common type of cancer. It occurs in children below 15 years of age.

It is a white blood cell cancer. The WBCs are produced in excess in the bone marrow.

The white blood cells produced in excess crowd the bone marrow.

It hinders the production of red blood cells and platelets.

The Types of Leukemia –

• Lymphocytic leukemia

• Myeloid leukemia

• Myeloblastic leukemia

The Commonly Used Anticancer Medicines in Leukemia –

Trexager 50 mg (Methotrexate injection)

Cytarzer 1000 mg (Cytarabine injection)

Dorucin 50mg (Doxorubicin injection)

What is Lymphoma?

It is cancer in the lymph nodes/lymphoid system.

It is the excess formation of WBC.

It occurs in lymph nodes, thymus, and spleen.

It includes –

• Non-Hodgkin lymphoma

• Hodgkin lymphoma

The Commonly Used Anticancer Medicines in Lymphoma –

Cyclophosphamide injection

Doxorubicin injection – Dorucin 50

Bleomycin injection – Bleokey

What are Brain Tumors?

It is the second common childhood cancer.

It is the excess growth of glial cells in the brain.

It consists of –

• Astrocytomas

• Ependymomas

• Optic nerve gliomas

• Embryonal Tumors

The Drugs include-

Carbokast 450 mg – Carboplatin injection

Trexager 50 mg – Methotrexate injection

Temzokey 500 mg – Temozolomide capsules

What are Spinal Cord Tumors?

It is the abnormal cell growth in the spinal cord tissue.

It includes –

• Intramedullary tumors

• Intradural tumors

• Extradural tumors

What are Solid Tumors?

It is excess mass growth in tissues or organs.

It includes tumors in the vital organs-

• Bone tumor

• Brain tumor

• Kidney tumor

• Tumor in the eye

• Skeletal muscle tumor

Symptoms of Childhood Cancers-

• Unexplained weight loss

• Chronic pain

• Tiredness

• Lumps or swelling

• Frequent bleeding and bruising

• Severe headache

• Changes in mood

• Digestive issue

• Loss of appetite

• Changes in vision

• Enlarged lymph nodes

The Treatments for Childhood Cancer

Chemotherapy – It forms an important part of the treatment for childhood cancers.

It is given in cycles. It targets the rapidly dividing cells.

It is given before surgery to shrink the tumor.

It is given as adjuvant therapy after surgery.

It can also be given as maintenance therapy.

Surgery is done to remove the tumor.

Radiation therapy is done to reduce the tumor size. It can be done before/after surgery.

Immunotherapy – Antibodies are used to destroy cancer cells.

Stem cell transplant – In this, bone marrow cells are replaced with healthy stem cells.

It then produces new normal blood cells.

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Aprazer Healthcare is the leading oncology injectable manufacturer, developing more than 30 cancer molecules.

Through cutting-edge technology and continuous research, and drug development, Aprazer is committed to manufacturing innovative, advanced treatments that match the global health standards.

Developing the widest range of generic anticancer medicines, we are the global exporter of anticancer medicines to 50+ countries.

Chemotherapy is an essential cancer treatment. A widely used cancer therapy.

It significantly improves the survival rates.

However, it causes a few side effects that are often misunderstood.

The common myths include-

1. Chemotherapy is Painful

Chemotherapy is given through different routes (Oral, IV, Intrathecal, intra–arterial).

The most common route is intravenous.

The drugs cause various side effects.

It leads to nerve damage or mouth ulcers.

It causes discomfort and pain.

2. Chemotherapy Makes One More ill

It causes temporary side effects. These effects subside after discontinuation of the therapy.

The side effects are manageable with supportive care.

Chemo causes side effects like-

• Nausea

• Vomiting

• Tiredness

• Hair loss

• Reduced blood count

3. Chemotherapy is Done Only in Advanced Cancer Stages

Chemotherapy is done at different cancer stages-

It is done at early cancer stages to advanced cancers.

It is done before the surgery to shrink the tumors.

The reduced size helps in easy elimination.

Chemotherapy is done after surgery to eliminate leftover cancer cells.

It is also used as maintenance therapy to prevent cancer recurrence.

Chemotherapy is used as palliative care. It is done when cancer is not curable.

It is done in advanced cancer stages to manage cancer symptoms.

4. One cannot Do Daily Routine Work During Chemotherapy

The side effects vary from each other.

It depends upon the dose and the drug.

The supportive care helps manage the effects.

One can easily continue the daily routine.

5. Chemotherapy Permanently Lowers Immunity

Chemotherapy suppresses the bone marrow.

It reduces the formation of blood.

It reduces the WBC count. It can lead to infections.

The drugs destroy even healthy cells. It disturbs gut health.

These are all temporary effects. They improve when the therapy is stopped.

6. Chemotherapy Always Causes Infertility

It can affect fertility in both men and women.

It depends upon the drug and the duration of chemotherapy.

It can cause both temporary issues and permanent infertility.

One must always consult the doctor before chemotherapy.

7. Chemotherapy Always Leads to Permanent Side Effects

Chemotherapy causes several side effects.

Most of them are temporary and improve after the discontinuation of the therapy.

Many of them continue for longer for months or years.

It can severely damage the internal organs.

Continuous monitoring of the therapeutic dose and body functions is required.

8. Chemotherapy Always Causes Bone Loss

Many chemotherapy drugs lead to an imbalance between bone cell formation and bone cell destruction.

It increases the chances of bone fractures/osteoporosis.

This reduction in bone density is effectively managed by supportive cancer therapies/drugs.

The Commonly Used Chemotherapy Medicines

Capecitabine tablets – Capekast 500mg

Temozolomide tablets – Temzokey 100 mg

Carboplatin Injection –Carbokast 150 mg

Cytarabine injection – Cytarzer 1000

Aprazer Healthcare – The Top Oncology Medicine Manufacturer

Aprazer Healthcare is the leading anticancer medicine manufacturer.

We manufacture the widest range of oncology oral and oncology injectable products.

Certified by the WHO-GMP, Aprazer Healthcare manufactures affordable generic anticancer medicines.

As the top oncology orals manufacturer, Aprazer is India’s leading pharmaceutical exporter.

We manufacture global quality pharmaceutical products.

Our affordability makes us approachable.

Polycythemia is a rare red blood cell cancer. The increase in RBC count causes several other effects, like metabolic dysfunction of the body, cardiac problems, and neurological problems affecting the overall body functioning.

What is Polycythemia?

It is a cancer of the red blood cells in which bone marrow starts to produce red blood cells in excess.

This causes serious complications, like thickening of the blood that interrupts blood flow.

Symptoms of Polycythemia

• Itchiness and vertigo

• Headache

• Swelling of the joint

• Reddish or purplish skin

• Numbness of hands and feet

• Unusual bleeding

• Pain in the bones

• Shortness of breath

• Trouble with breathing

• Bloating and pain in the upper abdomen

Complications Caused by Polycythemia Vera

Blood Clot – The excess blood cells, thickening the blood and forming clots due to abnormal clumping of platelets. The blood clots increase the risk of cardiac dysfunction, causing heart attacks, strokes, clots in the legs and lungs, causing a life-threatening condition.

Enlarged Spleen – The extra blood cells increase the load on the spleen to increases its surface area to filter more blood. The enlarged spleen causes many gastrointestinal problems, like pain under the ribs, a feeling of fullness after a small meal.

Peptic Ulcers – The abnormal blood cells increase the release of histamine, irritating the stomach lining, leading to ulceration. It leads to the formation of open sores on the intestinal and esophageal lining.

Gout and Kidney Stones – The increased metabolism of the excess red blood cells causes an increase in uric acid production, leading to the formation of gout and stones in the kidney.

It causes pain in the joints and also dark urine or blood in the urine.

Bleeding and Bruising – A small cut or injury leads to excessive blood flow due to an imbalance between platelet count and RBC count, as caused by excess RBC.

Other Blood Disorders – Polycythemia Vera, if untreated, lead to bone marrow scarring and progress to leukemia or Myelodysplastic Syndrome (MDS), producing infectious blood.

Diagnosis of Polycythemia Vera

Polycythemia is diagnosed through various processes and testing-

Blood Test – Total blood count or increased blood volume, low erythropoietin levels, and excess hemoglobin.

Bone Marrow Biopsy – Bone marrow tissue or the fluid is taken from the stem cells to examine the abnormal production of blood cells. It is used to diagnose various blood disorders like lymphoma, leukemia, anemia, etc.

Genetic Testing – DNA testing is done to identify various genetic mutations possible to cause Polycythemia.

Treatment of Polycythemia Vera

Blood Withdrawal – It is the manual removal of the extra blood formed in the body through a vein. It is done regularly, depending upon the severity of the disease.

The blood removal in polycythemia reduces various other complications, like stroke or blood clots.

Low-dose Aspirin – Sometimes low aspirin doses are given to reduce the risk of clotting and stroke.

Targeted Therapy – It includes the drugs that target the mutated genes.

Other Medications – They include medicines for symptomatic relief.

Like – Allopurinol for gout.

Antihistaminic drugs to reduce itching.

Medicines to Reduce Blood Formation

It includes chemotherapy drugs. They inhibit blood cell proliferation in the bone marrow.

Aprahydro (Hydroxyurea Capsules)

It is a widely used medicine for blood cancer.

It starts with a dose of 500mg twice a day.

It inhibits the enzyme that converts RNA to DNA.

It inhibits cancer cell propagation.

It is widely used in –

• Sickle Cell Anemia

• Myeloproliferative Disorders

Busulfan – It directly damages the cancer cell DNA, inhibiting cell proliferation. It is widely used in polycythemia Vera to reduce excessive blood count, in bone marrow transplant, and various other myeloproliferative disorders.

Interferon – It is widely used in young adults or childbearing women for polycythemia, myeloproliferative disorders (PV, ET, myelofibrosis), and other viral infections.

It enhances the immune system and targets the signaling pathway for cancer cell proliferation.

Ruxolitinib – It is used in various blood cancers, targeting the cancer cell proliferation pathway.

It decreases spleen size. It reduces blood cell formation.

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Aprazer Healthcare is the leading anticancer drug manufacturer, developing a range of effective anticancer solutions.

Reaching worldwide with effective, innovative solutions and targeted therapies, Aprazer Healthcare marked a leadership in oncology drug development and is the leading exporter of oncology medicines worldwide.

We are at the forefront in developing new drug molecules for effective cancer treatments.

We manufacture the widest range of affordable anticancer generics medicines.

Know-How and Why?

Erectile dysfunction and heart disease have the same cause.

In both disorders, the blood vessels are blocked

The arteries in the penis are narrow.

The blockade in the blood flow occurs at first in the penile arteries.

Erectile dysfunction can be a signal for later heart disease.

What Causes Blood Vessel Damage?

The blood vessels are damaged by—

Atherosclerosis — It is an interruption to the flow of the blood.

It is the plaque buildup in the arteries.

It causes the arteries to harden and stiffen.

Endothelial Dysfunction — it is when the inner lining of the blood vessels is damaged.

It interrupts the blood circulation.

Artery Size – The penile arteries are very small in size.

The blockade to blood flow immediately shows up in the penile glands.

The plaque deposition occurs at first in the small arteries.

The Factors that Put You at Risk of Erectile Dysfunction and Heart Disease

Diabetes – The blood sugar damages the inner lining of blood vessels.

It leads to a buildup of plaque. It leads to nerve damage.

It affects nerves and blood vessels in the penis and the heart.

Cholesterol – High cholesterol levels get deposited in the arteries.

It causes plaque to build up in the arteries.

It interrupts the blood flow to the penis as well as the heart.

Obesity – Excessive fat leads to plaque buildup in the blood vessels.

It can cause high blood pressure.

It leads to inflammation in the body.

It can disrupt the walls of blood vessels.

High Blood Pressure — The excessively high bp causes wear and tear of the blood vessels.

It causes narrowing of the blood vessels.

It leads to stiffening of the blood vessels.

Sedentary Lifestyle – The inactivity leads to obesity. It reduces the blood circulation.

It weakens the cardiac muscles.

It leads to inflammation. It leads to increased cholesterol in the blood.

Age – with the increasing age, flexibility of the blood vessels reduces.

It causes reduced blood flow.

Low testosterone levels lead to a lowered sexual urge.

It greatly reduces the libido.

Smoking – The use of tobacco damages the blood vessels.

It causes narrowing of the arteries.

It impairs blood flow.

Key Points –

Erectile dysfunction can indicate the start of cardiovascular disease. It is important to diagnose the underlying causes and risks.

The necessary steps to reduce the risk include-

• • Stop smoking
• • Exercise
• • Better diet

It reduces the risk of cardiac diseases.

It leads to better erectile functioning.

What Can Be the Role of Erectile Dysfunction Medicine?

Erectile disorder is not cured by ED medicines.

The ED medicines play a role in improving sexual function.

They increase the blood flow to the penis.

It relaxes the muscles of the penis. It leads to an erection.

It is widely used to bring on an erection during the time of intercourse.

The Types of Sexual Dysfunction Medicine

Erectile Dysfunction Medicine – These medicines cause an erection.

It is used by men 30 minutes before sex.

Viabest 100 – Sildenafil Citrate 100mg

Tadabest 40 – Tadalafil 40mg

Premature Ejaculation Medicine – It is the medicine that causes delayed ejaculation.

It is also used 30 minutes before sexual activity.

Dapobest 60 – Dapoxetine Hydrochloride 60mg tablets

Dapobest 30 – Dapoxetine Hydrochloride 30mg tablets

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Recognized in India as the top erectile dysfunction medicine manufacturer, Aprazer Healthcare is a leading erectile dysfunction medicine exporter.

We manufacture top-quality, affordable erectile dysfunction medicine.

Our medicines are available worldwide.

We manufacture global-quality medicines for erectile dysfunction and premature ejaculation.

Keeping in mind the over-the-counter use and patient safety, we strictly adhere to the regulatory norms.

We are committed to manufacturing safe, effective erectile dysfunction medicines.

India is next to China, having a significant number of hepatitis B cases.

The highest prevalence of hepatitis B infection is in tribal regions.

The states having the highest hepatitis B burden include –

• • Andaman Nicobar Islands
• • Arunachal Pradesh
• • Odisha
• • Telangana
• • Northeast parts
• • Punjab
• • Haryana

The Primary Causes of Hepatitis B in the Tribal Community

Hepatitis B spreads through viral transmission.

It transfers through blood and body fluids.

The important factors that lead to its spread –

Unsafe Practices

The traditional practices are usually done in villages.

They are done without sterility management.

It is the use of unsterile equipment for –

• • Nose piercing
• • Ear piercing
• • Tattooing

The traditional practices like sacrificing, bloodletting.

Poor Living Conditions

Hepatitis B spreads easily. It gets transferred through infected food items and drinks.

The insanity conditions. Due to limited access to essential utilities, people share things of personal items.

• • Razors
• • Nail clippers

Unsafe Medical Procedures

The unprofessional use of medical treatments.

Use of contaminated surgical instruments.

Administration of infected body fluids.

Sharing needles, blades during surgery.

Lack of Awareness

The poor knowledge of sanitation. The lack of awareness about symptoms and disease causes.

The risk increases with unusual contacts, unprotected sex.

It leads to the spread of infection.

Poor Healthcare Access

Lack of vaccination in rural areas.

People unaware of the healthcare diagnosis or precautions lead to an increased risk.

Social stigmas about the disease hinder their approach to getting medical help.

Often, the unavailability of hospitals or laboratories, people miss the testing and timely diagnosis.

Mother to Child Transmission

Often, the mother remains undiagnosed and untreated. Hepatitis B is transmitted from the infected mother to the child.

The transfer of infection can be prevented by immunization of the child.

How Can We Prevent Ourselves From Hepatitis B Infection?

Hepatitis B is a viral infection. It spreads from the external environment.

It can be prevented through several means.

• • Practicing safe sex
• • Maintaining hygiene
• • Using sterile medical equipment’s
• • Avoid sharing personal items
• • Avoid administration of infected body fluids.
• • Timely vaccination

Is Hepatitis B Curable?

Hepatitis B is a lifelong disease. It cannot be cured. However, it can be managed through antiviral therapy.

The antiviral drugs significantly reduce the viral count.

The viral count reaches the undetectable level. The undetectable virus count reduces the risk of transmission.

Prevention plays an important role in stopping transmission.

Aprazer Healthcare- Making Hepatitis B Treatment Affordable in Tribal India

Aprazer Healthcare is the leading hepatitis B medicines manufacturer in India. We manufacture the highest quality antiviral products.

Manufacturing the generic antiviral drugs, we offer an affordable range of hepatitis B medicines.

We have multiple manufacturing plants. We manufacture the widest range of antivirals, including direct-acting antivirals and antiretroviral medicines.

Adhering to the highest healthcare standards, we manufacture global quality medicines.

Having a robust distribution system, we ensure the hepatitis medicines reach the remote corners of India.

Aprazer Healthcare Aims to Control HBV in Vulnerable Communities

Extending our reach to the tribal areas and the regions with the highest number of hepatitis B cases, like Punjab, Haryana, and the northeastern states. We are the largest hepatitis B drug supplier in Haryana.

In the tribal area of Haryana, we supply the bulk hepatitis B medicines to the private clinics, hospitals, and government dispensaries.

Collaborating with private partners and government agencies. We are the top hepatitis B medicine manufacturer in India and the bulk suppliers.

The Affordable Hepatitis B Medicines in Haryana

Aprazer Healthcare manufactures affordable hepatitis B medicines.

Our product range consists of –

• • Tenofovir Alafenamide 25mg Tablet- Tafnext
• • Entecavir Tablets 1 mg – Entekor -1
• • Tenofovir Disoproxil Fumarate Tablets – Tudobest

Conclusion

Aprazer Healthcare stands at the forefront with a mission to eradicate Hepatitis B from India.

We manufacture affordable hepatitis B medicine, accessible to all.

Without compromising the quality, we are committed to manufacturing the highest quality products.

(WHO-GMP certified).

We are the largest manufacturers and suppliers offering a pan-India supply of Hepatitis B medicine.

It is the sexually transmitted infections that increase the risk of anal cancer.

The HPV infection forms a primary factor in the majority of cases.

HPV strains 16 and 18 directly cause changes in the anal cells.

It infects the inner lining of the anus.

It enters the body through sexual activity.

Genetic changes lead to rapid cell division.

What is Anal Cancer?

Anal cancer is formed in the anal canal. It is the last part of the digestive system.

It is a tube-like passage. It links the rectum to the anus.

What Are the Anal Cancer Types?

Squamous Cell Carcinoma – It is the cancer that occurs in the lining or the top skin layer covering the anus. It is usually caused by HPV or HIV infection. It is the common type of anal carcinoma.

Adenocarcinoma – It is a cancer that starts in the adrenal glands present in the organ. It is caused in the sweat glands, present in the skin around the anus, or the adrenal cells in the upper anal canal. It is a rare form of anal cancer.

What Are Anal Cancer Symptoms?

• • Bleeding through the anus
• • A lump or mass in the anus
• • Pain in the rectal area
• • Leaking of the stool
• • Changes in stool consistency and bowel movement
• • Abnormal rectal discharge
• • Discomfort in the rectum

Other Risk Factors for Anal Cancer

Having multiple sex partners – It increases the risk of infection.

The sexually transmitted viruses include –

• • HIV
• • HPV
• • Chlamydia

Anal sex- the infection enters through the anal route.

Smoking – use of tobacco or cigarettes, with years of use, increases the risk of developing cancer.

Age – The risk of anal cancer increases with age, above 50 -55.

Weak immune system – It increases the risk of HPV, HIV infections.

Previous cancer treatment – The radiation therapies used in ovarian or uterine cancer increase the risk.

Immunosuppressant – the weekend immunity increases the risk of cancer-causing infection.

The Anal Cancer Treatments

Surgery – It is the removal of the localized tumor. The tumor which has not involved the surrounding muscles and tissues.

Chemo-radiation forms an important part of treatment. It includes chemotherapy and radiation.

• • Radiation therapy – It is the use of high-intensity rays to kill cancer cells. It is focused on the tumor cells. It can be both internal and external.
• • Chemotherapy – The cytotoxic drugs kill the cancer cells. Given before surgery, it shrinks the tumor. It is given after surgery to eliminate leftover cancer cells. It is given in cycles with radiation therapy.

Chemotherapy Medicines Used in Anal Cancer

Two or more drugs are given in chemotherapy treatment at the same time to shrink the tumor/cancer.

The chemotherapy drugs are given in the form of cycles, including rest days.

The commonly used combinations involve –

• • 5-fluorouracil (5-FU) and Mitomycin.
• • 5-FU and Cisplatin(Cycokast)

For aggressive advanced stages of cancer, other drug combinations include-

• • Carboplatin(Carbokast) with paclitaxel (Paclikast)
• • 5-FU with cisplatin(Cycokast)
• • Oxaliplatin(Oxazer) , Leucovorin(Leucokast) and 5-FU
• • Docetaxel(Docekast) , Cisplatin(Cycokast), and 5-FU
• • Cisplatin(Cycokast) , Leucovorin(Leucokast) and 5-FU

The Trusted Anticancer Injections Manufacturer by Aprazer

With the evolving diagnostic landscape, we are focused on developing advanced anticancer medicines.

The innovative cancer treatments, including targeted anticancer medicines, chemotherapy medicines, increase the survival outcomes.

Aprazer is the leading oncology injectable manufacturer that develops advanced anticancer injections.

With a patient-centric approach and empathy, Aprazer develops a range of affordable generic anticancer medicines and anticancer injections.

• • WHO-GMP certified manufacturing capacities
• • Continuous Research and drug development
• • Leveraging cutting-edge technology

Aprazer’s products, owing to their high-quality standards and safety, are highly prescribed by leading oncologists in the world.

We are the bulk exporter of affordable anticancer injections to the leading hospitals, oncology care settings, and clinics.

Aprazer Healthcare, a long-standing leader in life-saving pharmaceuticals.

Aprazer Healthcare is committed to addressing the rising demand for anticancer medicines in India.

It is the top Indian pharmaceutical company.

As the leader in cancer care, Aprazer stands out as the top anticancer medicine distributor in Delhi.

We specialize in manufacturing a range of –

• • Anticancer Tablets and Capsules
• • Anticancer injections

The Cancer Challenge in Delhi

Delhi faces a significant cancer challenge. The highest incidence of cancer is found in Delhi.

The critical rise in cancer is attributed to pollution and lifestyle.

• • Poor air quality
• • Untreated industrial waste
• • Vehicle emission
• • Untreated sewage
• • Lack of physical activity
• • Poor diet
• • Lack of awareness
• • Delayed diagnosis

How is Aprazer Healthcare Contributing to Cancer Care?

Aprazer Healthcare is committed to meeting the demand for affordable anticancer medicines.

With more than 7 manufacturing plants in India, Aprazer stands as the largest oncology oral manufacturer in India.

We have the largest oncology oral plant at Haridwar spanning an area of 70000 sq. ft.

Our valuable strategy focuses on a patient-centric approach for affordable, high-quality care.

Affordable Anticancer Medicines – Manufacturing a range of generic anticancer drugs, we ensure affordability meets quality.

Without compromising the quality, we manufacture anticancer medicines with equivalent therapeutic efficacy and safety.

Extensive Product Portfolio – Aprazer Healthcare manufactures more than 300 molecules.

We manufacture advanced anticancer medicines and injections.

We offer the widest range of anticancer drugs, including –

• • Chemotherapy medicines
• • Hormone therapy medicines
• • Targeted therapy medicine

Strong Supply Chain – We have the largest distribution network.

We aim to bring anticancer care accessible to all.

Temperature-controlled shipments enable us to deliver safe, secure anticancer medicines across India.

Collaborations with Leading Hospitals

Partnership with the top hospitals in Delhi and across India makes us the leading anticancer medicine suppliers in Delhi.

We are the bulk anticancer medicine supplier to NGOs and the leading government institutions.

Why Aprazer Healthcare is the Top Anticancer Medicine Manufacturer in India?

With state-of-the-art manufacturing infrastructure, we continue to develop world-class manufacturing facilities equipped with cutting–edge technology, automated processes for quality controls, and quality assurance.

Global Standards of Manufacturing

We closely adhere to WHO and EU-GMP health standards.

It ensures our commitment to manufacturing safe, effective medicines.

Good Manufacturing Practices

We adhere to strict regulatory advisory.

We implement proactive strategies.

• • Implementing quality control systems
• • Regular quality audits
• • Proper documentation

Quality Assurance

We use the DMF quality API.

We use the finest quality raw material.

We manufacture potent, precise, and well-tolerated drug formulations.

Innovation-Driven Manufacturing

We specialize in manufacturing complex anticancer therapies, the targeted medicines.

Equipped with advanced technology, we manufacture the latest anticancer therapy medicines and anticancer injections.

Manufacturing a range of anticancer injections, we are the top oncology injectable manufacturers.

RTU Technology Injection – Apragem (Gemcitabine Injection)

Pre-filled Anticancer Injections – Fulvekast (Fulvestrant Injection 250mg/5ml)

Global Reach & Market Presence

We are India‘s leading anticancer medicine exporter to more than 50 countries. Our trusted medicines are widely used in Africa, America, and Asian countries.

Aprazer Healthcare is a leading name in global markets.

With our effective distribution network, we ensure a consistent supply of quality products to meet the needs of remote markets.

Alcohol affects health and body functioning.

It may not always cause cancer. But it certainly increases the risks.

It promotes cancer formation in high-risk people.

The Damaging Process of Alcohol

Formation of acetaldehyde-

Alcohol when metabolized in the liver. It forms acetaldehyde.

It is cytotoxic and cancerous.

It affects the body in many ways.

• • DNA damage – Acetaldehyde directly damages the DNA. It causes mutations in the DNA structure.
• • Hormonal changes- Alcohol increases the estrogen levels. It causes rapid cell division. It affects estrogen-dependent breast cancer. It alters other androgens and gonadotropins in men. It increases hormones that propagate prostate cancer.
• • Inflammation – It causes oxidative stress. It forms a reactive oxygen radical. It causes inflammation in the gut and the entire body.
• • Nutrient malabsorption- It erodes the gut lining. It leads to the formation of leaky gut. It impairs absorption.
• • Affects the liver – Alcohol alters liver function. It impairs fat metabolism. It leads to fat deposition in the liver. It leads to alcoholic fatty liver.
• • Weight gain – Alcohol is rich in calories. It is difficult to metabolize. It increases the weight. It also increases appetite. Alters hormone and decreases sleep.

7 Types of Cancers Are Directly Linked to Alcohol

• • Bowel cancer
• • Breast cancer
• • Throat cancer
• • Liver cancer
• • Mouth cancer
• • Food pipe cancer
• • Cancers of the respiratory system

Why Avoid Smoking With Alcohol?

When alcohol and tobacco are used together. It increases the risk of cancer manifold.

Alcohol increases the solubility of carcinogenic elements present in cigarettes.

It increases absorption in the mouth and throat. It enhances mucosal layer permeation.

• • It damages DNA
• • It weakens the immune system

Alcohol increases the enzyme activity. It leads to the rapid breakdown of cancerous components.

What is Alcohol Dependence?

Long-term regular use of alcohol causes dependency.

The body gets used to alcohol.

It is a condition in which the body needs more alcohol to produce similar effects.

The person is unable to control alcohol intake.

Alcohol dependence causes-

• • Cravings
• • Drinking in excess
• • Withdrawal symptoms
• • Inability to stop drinking
• • Binge drinking

It shows withdrawal symptoms when not drinking. It leads to several physical, emotional, and mental symptoms, like –

• • Nervousness
• • Anxiety
• • High BP
• • Irregular heartbeat
• • Sweating

What Are the Immediate Alcohol Effects on the Body?

Alcohol causes several CNS effects-

• • Changes mood
• • Blurred vision
• • Slow thoughts
• • Difficulty in standing erect
• • Slurred speech
• • Vomiting
• • Dehydration

When consumed in large amounts, it causes –

• • Memory loss
• • Drowsiness
• • Inability to stand

What Are the Alcohol Effects on Our Health?

Chronic use of alcohol leads to –

• • Anxiety
• • Sleep disorder
• • Liver disease
• • Pancreatitis
• • Decreased libido
• • Cardiac diseases
• • Weakened immune system
• • Damages brain cells
• • Fertility problems

Changing the Myths Around Alcohol

Alcohol is widely believed to prevent cardiovascular risk. In actuality, it does not decrease the risk that significantly. Rather, its side effects are more prominent and lead to long-term repercussions.

It is commonly said that alcohol increases sexual power. But it leads to erectile dysfunction. It reduces sexual urge in both men and women.

Alcohol used in any beverage breaks down to acetaldehyde. It is the same whether in the form of a bear or shorts.

Conclusion

Alcohol consumption is the leading cause of several cancers.

It is a preventable risk. No amount of alcohol is good to use.

Aprazer Healthcare– Empowering Lives through Cancer Awareness

As the leading anticancer medicine manufacturer, Aprazer stands at the forefront of eradicating cancer.

Together, we can build safe futures.

Identifying cancer risks, knowing cancer at the earliest, helps better prognosis.

Controlling the risks can reduce cancer rates and mortality.

We continue to invest in advanced drug research and development.

We are focused on providing better treatments with guaranteed outcomes.

We are the top anticancer drug exporters from India to countries in Africa, South America, and Southeast Asia.

What is Metastatic Cancer?

The cancer that spreads from the primary cancer site to different locations.

It is a process in which the cancer cells travel in the body.

The tumor cells spread through –

• • Lymphatic system
• • Blood vessels

The Types of Metastatic Cancer

Local Metastasis

It is the spread of cancer cells to the nearest region.

The cancer spreads to the neighboring –

• • lymph nodes
• • Tissues.

Regional Metastasis

The cancer has spread into the nearby region.

It occupies the same region.

The cancer has not spread beyond the region.

Distant Metastasis

It is the condition that cancer cells reach other organs.

It is the process that cancer has covered far-off regions.

The Process by Which Cancer Spreads

It is a complex process-

• • The cancer cells are detached from the tumor.
• • The cancer cells reach nearby tissues.
• • The cancer cells travel into the blood vessels and the lymph system.
• • They get attached to platelets or blood capillaries.
• • The tumor cells reach distant organs.
• • The tumor cells start growing into small masses.
• • The small tumors develop new blood vessels.
• • The small masses grow into large tumors.
• • The tumor cells evade the immune system.

What is Advanced Cancer?

The advanced cancer is the cancer that has reached the last stage.

The cancer that cannot be cured. It is generally the 4th stage of the cancer.

It includes –

Metastasized Cancer –

The cancer that has spread from other parts.

The cancer cells often spread in the advanced stage.

The cancer has spread to organs and tissues that are distant.

It is the secondary tumor that has started growing in distant organs.

Locally Advanced Cancer –

It is the stage of cancer in which the cancer has grown into the neighboring tissue.

It is usually called stage 1 or stage 2 cancer.

Are Metastatic Cancers the Same Cancer?

The metastatic cancers are the same original cancer cells.

It is the same cells that spread to distant organs.

Examples of Metastatic Cancers –

1. The breast cancer that has spread to lung is metastasized breast cancer.

It is the breast cancer cells that have reached the liver.

2. If the lung cancer spreads to the brain. It is not brain cancer. It is the same lung cancer.

The Treatment Approach for Metastasized and Advanced Cancers

The treatment for advanced or metastatic cancer includes managing the chronic condition, extending survival years.

Treating cancer effects and improving quality of life.

It included systemic therapies-

• • Chemotherapy – It is the use of toxic drugs. The drugs kill the cancer cells.
• • Targeted therapy – It is the use of drugs that target cancer cells.
• • Hormone therapy – It is the drugs used that inhibit hormone secretions. It is widely used for hormone-dependent cancers.
  Example – Breast cancer
  Prostate cancer
  Thyroid cancer
• • Immunotherapy – It stimulates the immunity of body. It is the use of proteins or antibodies that attack the cancer cells.

Local therapies include –

• • Radiation Therapy – It is the use of radioactive material. The rays from the isotopes are concentrated on the tumor to kill the viable cells.
• • Surgery

Why is Palliative Cancer Treatment Important?

The palliative care includes –

• • Managing the symptoms of cancer.
• • Cancer treatment side effects.

It is the use of injectables, which are given alongside the cancer treatment.

Zoledronic Acid Injection – Zoldokast

It is used to prevent bone degradation by cancer therapy.

It restores bone strength and health.

It is used to manage skeletal-related events.

Leucovorin Calcium Injection – Leucokast -50

It is used in cancer supportive treatment.

It is used as a rescue therapy to revive the folic acid.

Various cancer drugs act by disrupting the folic acid synthesis in the body.

Glutathione Injection – Glutakast

It is the antioxidant. It is used to restore healthy cells of the body.

To detoxify the cancer therapy effects from the body.

It is cyto-protective.

It prevents healthy cells from damage.

The Affordable Top–Quality Chemotherapy Injections

• • Cisplatin Injection – Cycokast 50
• • Carboplatin Injection – Carbokast -450
• • Doxorubicin Injection – Dorucin
• • Gemcitabine Injection- Apragem
• • Daunorubicin- Daunozer-20

Aprazer Healthcare- The Leading Oncology Injectable Manufacturer

Aprazer Healthcare is an oncology drug manufacturer from India. With global collaboration and presence, Aprazer positioned itself as the leading oncology drug exporter from India.

We manufacture the top-quality anticancer injections and the injections for palliative cancer care.

Maintaining a robust supply chain network, with efficient cold chain management, we are the top oncology injectable exporters.

There is always a fear surrounding organ transplants. Despite advancements in science and treatment, myths prevail about its surgery and its outcomes.

Kidney transplants can save lives. The modern medications and advanced surgery are effective in extending survival rates.

Unraveling the Fears Behind a Kidney Transplant

1. Is a Kidney Transplant Only for Young People?

People of all ages can donate or receive a kidney. It extends the survival rate in the elderly with a last-stage kidney disorder.

The kidney transplant depends upon the overall health of the person. It is affected by the medical conditions of a person.

2. Is the Post-transplant Care Lifelong and Expensive?

The organ transplant surgery covers the major cost.

The medications that are to be used after surgery are available at an affordable price.

The top nephrology medicine manufacturer, Aprazer Healthcare, manufactures top-quality, affordable transplant medicines.

3. Can a Donor Survive With One Kidney?

A kidney is transplanted after a complete evaluation of overall health.

A healthy person can easily live with one kidney.

The surviving kidney can compensate for the functions of the other kidney.

It does not decrease survival years.

There is no decline in a person’s normal working ability.

4. Is the Kidney Transplant Often Rejected Initially?

The advanced immunosuppressant medicines are used before the surgery. It prepares the body for an organ transplant.

The continuous therapy of immunosuppressant after surgery prevents rejection.

It includes-

• • Close monitoring.
• • Adherence to medicines

The best anti-rejection medicines used in a kidney transplant –

• • Myfocept (Mycophenolate Mofetil)
• • Xgraf (Tacrolimus)
• • Myfocept-S (Mycophenolate Sodium)

5. A Kidney Donor Should Always Be a Live Donor

A kidney can be taken from a person who has just died.

It is not a dead kidney. It is saved in machines that provide it with vital nutrients and components.

In case of unavailability of a live donor, the kidney of the deceased person can be a life-saving option.

6. One cannot Have Children After a Kidney Transplant

After a successful transplant, the fertility is revived.

The fertility is impaired during dialysis.

People after a kidney transplant can give birth to a healthy child through proper care.

7. You Should Always Have the Same Blood Group for a Transplant

With the advancement of science, the kidney can be transplanted easily. Various techniques are used to prevent blood group interactions.

The technology like –

• • Removing blood group antigens
• • Suppressing antibody production
• • Plasmapheresis

Conclusion

It is always important to know the facts for better healthcare outcomes.

Kidney transplant offers a better option over dialysis. It is a cost-effective process over dialysis.

Kidney transplant extends survival, offering hope to people with kidney failure.