India is recognized for affordable, standard -quality drug exports.

It is the largest manufacturer and exporter of anti-retroviral drugs.

India procures about 70% of the generic HIV antiretroviral demand.

It supplies about 22% of generic hepatitis antiviral drugs.

Why is India the global market for antiviral drugs? 

Indian manufacturers supply antiviral drugs to 200 + countries.

It is the leading and trusted supplier to international bodies like –

UNICEF and Médecins Sans Frontières

India leads the way due to –

• Low-cost production
• Advanced technology
• Large- scale generic manufacturing

The antiretroviral combinations exported from India- 

• Abacavir 600mg/Lamivudine 300 mg Tablets- Abakast-L
• Lopinavir and Ritonavir USP Tablets- Lopinavir
• Tenofovir Disoproxil Fumurate, Emtricitabine & Efavirenz Tablets- Virarazer

The commonly exported Hepatitis B drugs-

• Entekor- 0.5- Entacavir 0.5mg tablets
• Tafnext – Tenofovir Alafenamide 25mg tablets

The commonly exported Hepatitis C medicines- 

• Sofokast Plus- Daclatasvir and Sofosbuvir Tablets
• Ledikast- Ledipasvir & Sofosbuvir Tablets

The leading antiviral drug manufacturer/exporter from India- 

Aprazer Healthcare is the top hepatology drug manufacturer.

We specialize in manufacturing –

• Hepatitis B medicines
• Hepatitis C medicines
• HIV medicines

We supply a wide range of antiviral drugs to 50 + countries.

Aprazer Healthcare is one of the leading antiviral drug exporters from India.

It is advised not to stop an antiviral drug regimen abruptly. Why?

Leaving antiviral treatment incomplete may lead to –

• Viral rebound/flare
• Drug resistance
• Treatment failure

Why is it important to check co-infections before taking antiviral drugs?

• To prevent severe liver flare-up 

Treating one virus may activate the latent virus.

Taking Hepatitis C medicines with an undetected hepatitis B may cause hepatitis B reactivation.

• Avoid drug resistance – 

Taking antiviral drugs in co-infection may lead to developing drug resistance.

Hepatitis B antivirals, when used in HIV co-infection, may lead to HIV drug resistance.

Though the drug is active against both viruses.

The dose may be lower to treat HIV.

HIV mutates to develop resistance against that drug.

• Managing immune reconstitution inflammatory syndrome – 

The anti-retroviral drugs improve immune functions.

The active immune system detects the hidden infections.

This leads to a massive anti-inflammatory response.

• Prevent toxic drug interactions – 

It helps prevent drug interactions.

Adding an antiviral drug regimen may disrupt how the liver processes medication.

Why choose Aprazer Healthcare for antiviral drug exports?

Aprazer Healthcare is the leading pharmaceutical company.

We manufacture a top range of antiviral products.

Our Anti-retroviral combinations are highly trusted and supplied globally.

Regulatory compliance – 

We adhere to WHO-GMP/EU-GMP compliant manufacturing.

Assured Quality – We follow global quality parameters and in-house quality practices to ensure high-quality, safe products.

Reliable Supply chain network- 

Partnering with authentic logistics, we have an integrated cold chain supply network.

Global reach – We supply antiviral drugs to countries in the Middle East, Asia, and Africa.

The kidney from the donor is evaluated.

It is matched with the recipient’s biological profile.

The post-kidney transplant care demands lifelong therapy.

The role of immunosuppressant drugs in a kidney transplant- 

The anti-rejection medicines lower the body’s immunity.

They prevent the body from attacking the foreign organ.

These form a vital part of the kidney transplant drug regimen.

What is the anti-rejection drug regimen for protecting the kidney graft?

The anti-rejection therapy includes a sequential approach-

Induction Therapy- It is the process of intense immune suppression during the transplant surgery.

High-dose anti-rejection drugs are given intravenously.

Maintenance Therapy – It is a lifelong therapy.

It forms the backbone of the treatment.

It consists of a triple drug regimen.

These prevent acute organ rejection.

It also improves long–term graft survival.

What is meant by triple drug maintenance therapy?

The combination of three drugs offers comprehensive protection by inhibiting T-cell activation and cell division.

Calcineurin inhibitor – These inhibit the enzyme responsible for T- cell activation.

The T- cells are the immune cells attacking the graft.

Antimetabolite –These drugs inhibit DNA replication.

The activated immune cells rapidly divide to form cloned cells.

The antimetabolites stop the multiplication of B and T immune cells.

Corticosteroids: These are anti-inflammatory drugs.

These suppress the inflammatory response to the foreign organ.

These inhibit the synthesis of inflammatory signals.

What are the common anti-rejection drugs used in kidney transplant?

• Tacrolimus – X-Graf
• Mycophenolate Mofetil – Myfocept-500
• Mycophenolate Sodium- Myfocept –S 180

As a leading nephrology medicine manufacturer, Aprazer Healthcare specializes in manufacturing kidney transplant medicines.

Following WHO-GMP regulations and leveraging new technology, we manufacture a global range of kidney transplant drugs (immunosuppressive agents) 

Why should one not skip immunosuppressant doses? 

Skipping drug doses can trigger –

• Acute organ rejection.
• Irreversible kidney damage
• Graft failure
• Antibody sensitization

It is advised to avoid common painkillers (NSAIDs) after a kidney transplant. Why? 

NSAIDs must be avoided as these are excreted by the kidneys.

These drugs constrict the blood vessels.

Reduces the blood flow to the kidneys, causing an acute renal injury.

Immunosuppressant (triple drug therapy) side effects- 

The three drugs interrupt insulin production.

It leads to the development of post-kidney transplant diabetes.

These also increase cholesterol levels.

It leads to high blood pressure.

Tacrolimus side effects – 

Higher doses may lead to –

• kidney stress
• Tremors
• Hair loss /thinning

Mycophenolate Mofetil/Sodium side effects- 

• Severe GIT distress
• Bone marrow suppression

Corticosteroid side effects- 

• Fluid retention
• Bone loss
• Anxiety

Why is Aprazer Healthcare a leading nephrology medicine manufacturer?

Aprazer Healthcare is highly trusted for its nephrology drug portfolio.

• WHO-GMP-compliant drugs
• Precision drug manufacturing

Aprazer Healthcare is the leading exporter of immunosuppressive agents. Kidney Transplant Medicine, Transplant Medicine Manufacturer

These are platinum-derived drugs.

Platinum drugs form the vital component of chemotherapy.

They are highly potent/strong, directly damaging the cancer cell DNA.

These are effective against solid tumors.

These are widely used in-

• Ovarian cancers
• Bladder cancers
• Testicular cancer
• Head and neck cancers

The commonly used platinum-derived chemotherapy drugs-

• Cisplatin injection – Cycokast 50 
• Carboplatin injection – Carbokast 450 
• Oxaliplatin injection – Oxazer 100 

Available worldwide, Aprazer Healthcare is a trusted oncology brand.

As the leading pharmaceutical manufacturer, we manufacture a wide range of oncology orals and oncology injectables.

Manufacturing regulatory-compliant, global-quality anticancer medicines, we are an oncology medicine exporter from India.

With the strongest distribution network, we are the leading oncology medicine suppliers to Asia, Africa, and America.

What is the working of chemotherapy drugs (cisplatin/carboplatin)?

These bind the nucleic bases of the cancer cell DNA.

They lead to faulty crosslinking between the DNA strands.

This structurally damages the DNA

It leads to cell death.

How to select Carboplatin or Cisplatin?

Cisplatin is highly potent and has a fast mode of action.

Carboplatin has low toxicity and slower activity.

Cisplatin is exclusively used in –

head/neck cancer, bladder cancer, and testicular cancer.

Carboplatin is widely used in ovarian and lung cancer.

Carboplatin is well tolerated compared to cisplatin.

Cisplatin side effects – 

• Renal toxicity
• Ear toxicity
• Permanent hearing loss
• Severe dehydration
• Severe vomiting
• Permanent nerve damage

Carboplatin side effects – 

• Bone marrow suppression
• Anemia
• Risk of infections
• Mild GIT upset /nerve damage

Why does the doctor sometimes shift the treatment from Cisplatin to Carboplatin? 

Carboplatin has a better safety profile.

It is used if the patient experiences –

• Severe toxicity due to cisplatin
• Weak and elderly patients
• People with renal dysfunction or hearing disorders.

However, cisplatin is stronger and is used in advanced aggressive cancers.

Chemotherapy drugs (carboplatin/cisplatin) are given in cycles. Why?

Chemotherapy is always given in cycles with a resting period between.

The rest period is given for recovery.

As the chemotherapy drugs are cytotoxic.

They massively kill the cancer cells as well as the healthy cells.

This leads to severe fatigue or a fall in blood count.

The purpose of rest-

• Recovery of healthier cells
• Prevents severe toxicity
• Provides a window for resting/left over cancer cells to proliferate and get targeted in the next dose.

Why is Aprazer Healthcare a chosen oncologist brand?

Aprazer Healthcare specializes in manufacturing anticancer drugs.

It is the largest generic drug manufacturer, offering affordable first-line treatments for cancers.

We manufacture globally accepted, regulatory-compliant pharmaceutical products.

We are the leading suppliers of Etoposide injection (Posiact) to Africa, America, and Asia.

With 10 years of experience in Injectable manufacturing, Aprazer Healthcare is recognized as the top oncology injectable manufacturer from India.

We manufacture a comprehensive range of chemotherapy injectables.

Our top range of anticancer injections includes-

• Carboplatin – Carbokast 450
• Cisplatin- Cycokast 50 
• Cytarabine- Cytarzer 1000 
• Daunorubicin – Daunozer -20 

Etoposide injection and its uses- 

Etoposide is a chemotherapy drug.

It is a plant–derived drug called an anti-neoplastic alkaloid.

It is widely used in lung cancer, testicular cancer, and leukemia.

Which brand to choose for Etoposide injection? 

Posiact is Etoposide 100mg /5ml.

Manufactured by Aprazer Healthcare, is a global quality formulation.

Affordable and available worldwide, Posiact is the first choice of oncologists.

What is the working of Etoposide injection?

It binds to the DNA.

Inhibits the enzyme and stops the sealing of the DNA strands.

It leads to cancer cell death.

Why is Aprazer Healthcare a leading Etoposide injection exporter?

Aprazer Healthcare manufactures global-quality Etoposide injection.

Adhering to international regulatory standards, we are the trusted global oncology drug exporter.

Global-Quality compliance 

• WHO-GMP compliant manufacturing
• In-house quality audits
• Modern technology

Worldwide distribution network- 

• Advanced logistics
• Cold chain supply
• Global reach
• Timely delivery

Long-term reliable partnership- 

With our transparent and fair dealings, we believe in building long-term relationships.

We are a leading partner to national governments for oncology injectable supplies.

Manufacturing affordable anticancer injections, we are at the front line delivering affordable standard anticancer care worldwide.

End-to-end regulatory support- 

Our team of regulatory experts is efficient in navigating the flexible regulatory norms.

• Dossier compilation
• Global approvals and drug registrations
• GDP- compliance
• Custom clearance

Why does Etoposide (Posiact) form a key treatment for lung cancer? 

It is the standard chemotherapy drug widely used in small cell lung cancer.

It is widely used due to its ability to destroy rapidly dividing cancer cells.

Lung cancer cells divide rapidly.

Etoposide targets the enzyme and inhibits division.

It is paired with platinum-based drugs to achieve the highest response.

It is also paired with immunotherapy drugs and used in multiple-stage treatment.

What are the typical Etoposide cycle timelines?

The standard treatment regimen consists of 4- 6 cycles.

The treatment lasts for 3-4 months.

Each cycle operates at 21 days (3-week) schedule.

Day 1-3 – The IV infusion is given for 3 consecutive days, and the day-1 infusion is combined with platinum drugs.

Day 2 to 21 – It is the period for rest and recovery.

No treatment is given during these days.

What are the adverse effects of Etoposide injection?

• Bone marrow suppression
• Anemia
• Risk of infections
• GIT distress
• Nausea /vomiting
• Mouth ulcers
• Injection site reaction

Always trust Aprazer Healthcare for effective global quality oncology injectables. 

Available at a lower cost, these bridge affordability gaps in cancer treatment.

Generic oncology drugs comprise 80% of the total volume of drug prescriptions.

The oncology injectable forms 5O% of the share.

Hospital pharmacies depend upon 52% of generic oncology drug distribution.

The affordable generics serve as a lifeline for low- and middle-income countries.

• Ensure long –term supplies – 

The generic drug manufacturer builds a consistent drug supply, reducing the burden on a single brand.

• • Cost–saving – They are affordable, ensure and reduce financial burdens on healthcare systems.

• Expand global treatment access- 

Generic drugs help expand treatment access beyond borders.

Generic Oncology Medicines: Turning Expensive Care into Essential Care

Expensive treatments have led to failure in access to treatment.

Generic drugs cost up to 80 percent of branded drugs.

The generic options increase market competition, forcing reduced prices.

It reduces the financial constraints on families/ healthcare systems.

The standard first-line generic chemotherapy drugs are listed as essential medicines by the WHO.

 Which are the common generic cancer drugs? 

• Cisplatin – Cycokast
• Carboplatin – Carbokast
• Paclitaxel – Paclikast
• Docetaxel – Docekast
• Imatinib – Imatikast
• Letrozole – Letrakast

How are generic cancer drugs manufactured?

Generic drugs are the brand-equivalent medicines.

They have the same active ingredient, bioavailability, safety, and efficacy as the branded drugs.

These follow a similar manufacturing process, undergo the same approvals and quality assurance.

The manufacturing of oncology drugs requires dedicated facilities and prevention of cross-contamination.

Isolated facilities: These are separate facilities for manufacturing cytotoxic drugs.

Laminated surfaces – The walls and roof are sealed.

It prevents any particulate contamination.

Air handling systems (HVAC) – These maintain negative air pressure to prevent cross–contamination.

Limited access – The manufacturing area is restricted. Only the working person can enter.

Unidirectional flow processes –Sealed pipelines and closed system transfers to prevent vapor flow in the room.

Validation /decontamination protocols- Equipment validation, surface cleaning, and clean rooms are necessary to prevent contamination.

Sterile operations – These include aseptic processing for injectables.

Personnel safety – Protective gear and clothing are used to prevent working staff from exposure to toxic drugs.

What makes Aprazer Healthcare the largest generic cancer medicine manufacturer?

Aprazer Healthcare leads the way in manufacturing anticancer drugs.

We are the leading cancer medicine exporters from India.

World-class infrastructure:

• Advanced technology
• Modern equipment’s
• In-house testing
• WHO-GMP compliant units

Regulatory adherence/compliance – 

We hold licenses and accreditation by global health authorities like WHO-GMP and EU-GMP.

We are a globally accepted oncology medicine manufacturer.

Robust quality control parameters- 

We follow a set of SOPs to ensure manufacturing processes and validation.

• In-house quality audits and checks.
• Strong purity control parameters.
• Finished product testing and stability protocols

Supply chain traceability – We ensure quality and authenticity from procuring the raw material to the finished dosage formulation.

Largest product portfolio- 

We manufacturer of a wide range of oncology orals and oncology injectables.

Our anticancer product portfolio spans-

• Chemotherapy medicines
• Targeted therapy medicines
• Hormone therapy medicines

Worldwide distribution network – 

We are the leading oncology drug exporter from India.

Leveraging advanced logistics technology, we are committed to delivering products on time, preserving integrity.

Aprazer Healthcare aims to make oncology care affordable and universal. 

HIV is an RNA virus.

The anti-retroviral drugs target the RNA virus at different stages.

These inhibit viral cell replication and multiplication.

These reduce the viral count to undetectable levels.

The commonly used HIV drugs-

• INSTIs- Dolutegravir
• NRTIs- Lamivudine, Tenofovir Alafenamide
• NNRTIs – Efavirenz, Doravirin
• Protease Inhibitors – Ritonavir, Darunavir

What are the antiretroviral combinations /common single pill regimens used in HIV treatment?

Antiretroviral combinations or single-pill regimens are different classes of anti-retroviral drugs combined to form a single pill.

Two or more drugs combined target HIV at different sites.

These offer more potent action.

The single pill reduces the burden of multiple drug regimens.

The combination exhibits fewer side effects than a single large-dose drug.

The commonly used HIV combinations – 

1. Abakast L – Abacavir 600mg/ Lamivudine 300 mg
2. Lopikast– Lopinavir and Ritonavir 200mg/50mg
3. Temirazer– Tenofovir Disoproxil Fumarate, Emtricitabine 300mg/200mg
4. Tudobest-L– Tenofovir Disoproxil Fumurate & Lamivudine 300mg/300mg
5. Tudobest-LE– Tenofovir Disoproxil Fumurate, Efavirenz & Lamivudine 300mg/600mg/300mg
6. Virarazer– Tenofovir Disoproxil Fumurate, Emtricitabine & Efavirenz 300mg/200mg/600mg

The largest HIV medicine manufacturer/exporter in India – 

Aprazer Healthcare is a WHO-GMP-certified drug manufacturer in India.

We manufacture and export top-quality HIV medicines.

We are the global exporters of antiretroviral combinations.

As a leading generic medicine manufacturer, Aprazer manufactures affordable medicines without compromising the quality.

The drugs used for pre-exposure HIV prophylaxis – 

The commonly used drugs that can be taken by people at high risk of infection.

Emtricitabine/tenofovir disoproxil fumarate- Temirazer

Emtricitabine/tenofovir Alafenamide

What is on-demand (2-1-1 schedule)?

It is the HIV preventive medication taken before sexual activity.

The two pills are taken 24 hours before sex.

Take one pill after sex at 24 hours.

Take another pill at 48 hours.

Having sex multiple times must be followed by taking pills on two consecutive days without sex.

Is HIV a curable disease? 

HIV is not curable. It requires lifelong treatment.

The anti-retrovirals effectively aid in lowering the HIV count.

These prevent disease progression.

They inhibit the spread of the virus.

Does HIV medicine prevent virus transmission from mother to child?

The HIV drugs taken during pregnancy significantly lower the risk of transmission.

The anti-retrovirals are used in pregnancy and labor.

These are also given to the infant for 4-6 weeks.

It prevents the child from developing HIV infection.

Can an undetectable viral count safeguard against virus transmission through sexual contacts?

The HIV medicines reduce viral count to zero (nil).

The virus is not able to mutate, replicate, or multiply.

It lowers the risk of transmission during sexual contact.

However, with a positive HIV count, the virus gets easily transmitted through body fluids.

Stopping the treatment after my viral count reaches undetectable levels. Is it safe? 

The HIV medicines do not eliminate the infection.

These suppress the virus.

Leaving the HIV drugs reactivates the virus to replicate and spread.

Anti-retroviral therapy is a lifelong treatment.

Sudden withdrawal overactivates the immune system, causing an immune flare.

Conclusion – 

HIV is highly manageable with anti-retrovirals.

Daily adherence to HIV treatment significantly lowers HIV multiplication and spread.

Aprazer Healthcare is committed to manufacturing a range of generic antiretroviral combinations, offering affordable access to HIV treatments worldwide.

The treatment regimen includes –

• Evaluation of viral count
• Testing for co-infections
• Evaluation of liver damage

It is then followed by an antiviral regimen and supportive therapies.

The direct-acting antivirals are well tolerated.

These cure 98% of infections.

What is the newest Hepatitis C treatment?

The Direct-Acting Antivirals –

These are the antiviral drugs that target the proteins /enzyme in the virus.

These inhibit the virus life cycle.

The varied class of antivirals is combined to provide an effective cure.

The drug combinations lead to 95 % virus elimination. 

• Prevents drug resistance- 

Hepatitis C is attacked at different sites.

It reduces the probability of viral mutation.

• Provides absolute blockage-

It blocks the cell cycle at multiple points.

• Higher efficacy- 

The combination therapy offers lower side effects and high cure rates.

The commonly used Hepatitis C combinations include – 

• Velakast- Sofosbuvir /Velpatasavir 400mg/100 mg
• Sofokast Plus- Daclatasvir and Sofosbuvir 60/400mg
• Sofokast- Sofosbuvir Tablets 400 mg
• Dacikast- Daclatasvir Tablets 60 mg
• Ribasure- Ribavirin Capsules 200mg
• Ledikast- Ledipasvir & Sofosbuvir Tablets

Is Hepatitis C curable?

Hepatitis C is cured by the daily oral regimen of DAAs.

These drugs inhibit the multiplication /replication of HCV.

The direct-acting antiviral combinations offer successful cure rates.

Does curing Hepatitis C once make you immune for the rest of your life?

The antivirals completely cure Hepatitis C.

It does not provide future protection.

The hepatitis C virus undergoes innumerable mutations.

The body does not produce protective antibodies against all genotypes.

The long-term hepatitis also leads to immune scarring.

The original virus may not return, but the body may interact with a new strain.

Which is the pan-genotypic Hepatitis C combination used globally?

Velakast (Sofosbuvir/Velpatasvir) manufactured by Aprazer Healthcare.

It is a fixed-dose combination containing –

• Sofosbuvir – 400 mg
• Velpatasvir – 100mg

It is a highly prescribed antiviral combination used in Hepatitis C treatment.

Beyond a comprehensive treatment, Velakast offers an affordable treatment regimen.

Benefits of Velakast (Sofosbuvir/Velpatasvir) 

• It is effective against all 6 strains of Hepatitis C.
• It can be used in children aged 3 years or older.
• It is safe to be used in advanced liver disorders.
• Easy dosing – Once daily pill for 12 weeks

Which is the top Hepatitis C medicine manufacturer and global exporter? 

Aprazer Healthcare (hepatology medicine manufacturer) is a top hepatitis C medicine manufacturer.

We are the largest drug exporter from India, manufacturing global-quality antivirals.

As a leading Pharma third-party manufacturer in India- Aprazer Healthcare manufactures a diverse range of generic and branded drugs.

Aprazer Healthcare is a trusted brand in the global markets.

Hepatitis B is a chronic disorder.

It is a virus-induced disease and can spread from one person to another.

The treatment approaches include –

• Prevention of disease progression
• To suppress the viral load
• Prevent liver damage
• Improve immune functions

The antiviral treatment for hepatitis B- 

The hepatitis B drugs prevent the replication of the hepatitis B virus.

These incorporate the fake nucleic bases into the virus.

It leads to chain termination.

These suppress the viral load and reduce the viral count to undetectable levels.

This prevents disease progression and spread.

What are the once-daily oral antivirals for Hepatitis B?

These are the nucleos (t) ide analogues used once daily.

• Have specific strengths
• Have long half-lives
• Offer a 24-hour blocking window
• Are well tolerated
• Stronger resistance barrier

These drugs improve liver function-

• Prevent liver inflammation
• Prevent liver scarring
• Lower the risk of liver cancer

The commonly used drugs include-

• Entecavir- Entekor
• Tenofovir Disoproxil Fumarate- Tudobest
• Tenofovir Alafenamide- Tafsure

Can the spread of hepatitis B be prevented by antivirals? 

These do not prevent the spread of Hepatitis B.

It just lower the risk of infection.

But do not eliminate the complete transmission.

• Always practice safe sex.
• Avoid sharing needle /personal items.

Can antivirals prevent Hepatitis B transmission from mother to child?

The antiviral drugs significantly lower the viral count.

It prevents the transmission of the virus from the mother to the child.

These are widely given in the 28th week of pregnancy.

However, the antiviral treatment is not enough for infant prophylaxis.

The commonly used Hepatitis B medicines in pregnancy-

Tenofovir Disoproxil Fumarate (TDF) – Tudobest

Tenofovir Alafenamide (TAF) – Tafsure

Which is the largest Hepatitis B medicine manufacturer/exporter from India?

As the leading hepatology drug manufacturer, Aprazer Healthcare manufactures a large range of liver medicines.

Targeting hepatitis B treatment, Aprazer Healthcare is the largest Hepatitis B medicine manufacturer.

We manufacture global-quality hepatitis B drugs.

We are the top drug exporters to countries in Asia, Africa, and America.

Our flagship products include the standard first-line treatment drugs –

Entekor- Entecavir tablets exclusive for global exports.

Entekast – Entecavir tablets available for domestic distribution.

Tafsure /Tafnext – Tenofovir Alafenamide tablets

Tudobest- Tenofovir Disoproxil Fumarate tablets

Aprazer Healthcare is a global pharmaceutical company.

It is trusted for top-quality products and worldwide distribution.

We are the largest generic drug manufacturer and exporter from India.

With a significant rise in chronic diseases, treatment access remains minimal.

Over 1/3rd of the global population lacks access to regular essential healthcare.

Medicines account for 40-60 percent of total healthcare expenditure.

At Aprazer Healthcare, we are committed to closing the affordability gap.

What is the need for generic drugs?

Generic drugs serve as a lifeline to essential healthcare.

Generic drugs are uncompromised in quality/safety.

They are accessible at much reduced cost.

Lowered drug costs not only save lives, it helps families reduce their financial burdens.

Why are generic drugs affordable?

Generic drugs eliminate the additional cost spent on research and drug development.

It makes the essential medicines affordable and easily accessible.

Aprazer Healthcare – A top generic drug manufacturer /exporter 

• Regulatory compliance-

We strictly adhere to the global manufacturing standards.

We are accredited with WHO-GMP and EU-GMP certification.

Follow stringent quality controls and validation.

• Extensive product portfolio- 

We manufacture drugs in all therapeutic segments.

Our product portfolio encompasses –

• Oncology orals
• Oncology injectable
• Hepatology medicines
• Critical care medicines

• A strong distribution network- 

With strong global footprints, we are a leading source of generic drugs in the global markets.

Our largest distribution network spans across Africa, America, and Asia.

Maintaining an intact cold chain supply, we preserve product integrity.

•  Research and drug development- 

We invest heavily in drug development/novel dosage forms.

We manufacture a range of –

Complex generics and targeted therapies.

• Specialized drug formulations- 

We specialize in manufacturing advanced drug formulations –

• Modified oral dosage forms
• Lyophilized injectable
• Prefilled syringes

• Cost-effective manufacturing 

Manufacturing affordable drugs without compromising quality.

With continues drug manufacturing process, it reduces wastage and preserves quality.

How to verify the quality of a generic drug manufacturer from India?

The authentic generic drug manufacturers are verified through their –

• Manufacturing drug license
• GMP certificate
• Certificate of analysis
• Bioequivalence data
• Market approvals

How do we support the distribution of generic products to your country?

We support our distributor in other countries for-

Product registration and approvals in the specific country

Provide export documentation (COPP, free sales certificate, etc).

Why Aprazer Healthcare is a choice for global partnerships?

Accredited with global standards, our core values consist of transparency and flexibility.

Our team of regulatory experts smoothly navigates the ever-evolving regulatory dynamics.

We are transparent in all our dealings and work in the best interest of our stakeholder.

Quality standards maintained by Aprazer Healthcare for generic drugs-

• Bioequivalence
• Pharmacopeial compliance
• GMP practices
• Stability data
• Batch testing and certification

What are the common approaches to cancer treatment? 

Cancer treatment involves a comprehensive approach.

It includes tumor removal, shrinking tumor growth, preventing tumor spread, and preventing future recurrence.

• Surgery – It is an invasive method that physically removes cancer cells /tumors.
• Chemotherapy – It is the systemic circulation of toxic drugs into the blood.

The agents kill the cancer cells circulating in the body.

• Radiation therapy- It is the use of high-energy particles on the tumor.

It kills the cancer cells and shrinks the tumor.

The types of medicines for cancer treatment- 

• Chemotherapy drugs-

These are the toxic agents, targeting the rapidly dividing cancer cells.

The chemo drugs are given orally as well as intravenously.

The commonly used chemotherapy drugs-

• Carboplatin Injection – Carbokast 150mg
• Doxorubicin injection – Dorucin-10mg
• Paclitaxel injection – Paclikast 260mg
• Capecitabine tablets – Capekast

• Hormone therapy drugs – 

These are the hormonal analogues.

They are effective against hormone–sensitive tumors.

These block the synthesis of hormones or block the receptors for hormonal function.

These are widely used in breast cancer/prostate cancer treatments.

The commonly used hormone therapy drugs for breast cancer –

• Letrozole – Letrakast
• Anastrozole – Anzakast

Drugs for prostate cancer-

• Enzalutamide –Indenza
• Bicalutamide- Bicazer 50mg
• Abiraterone- Abirakast 500 mg

1. Targeted therapy drugs – 

These are drug formulations having targeted action.

They directly act on the cancer cells.

These have fewer side effects.

These do not harm healthy cells.

The common medicines include-

• Olaparib-Olabir 150mg
• Palbociclib- Palbocib-125 mg

• Immunotherapy – 

These work by enhancing the body’s immune system.

They increase the immune activity to destroy the cancer cells.

Examples include –

• Monoclonal antibodies
• Immune checkpoint inhibitor
• Cytokine inhibitors

Which are the 5 deadliest cancers?

1. Lung cancer 

It is the most prevalent cancer leading to cancer deaths globally.

It is often diagnosed at advanced stages.

2.5 million Cases are diagnosed every year.

2. Colorectal cancer –

It is the next leading cause of cancer deaths.

The benign polyps turn into cancer after 10 -15 years.

3. Liver Cancer- 

It is an aggressive form of cancer.

It is directly linked to Hepatitis B and C viral infections /alcohol use.

4. Stomach cancer – 

Stomach cancer accounts for 700,000 to 800,000 deaths annually.

It accounts for 5 % of all new cancer diagnoses.

5. Breast cancer –

It is the most common female cancer.

It accounts for 25% of cancers in women.

1 in 8 women is at risk of developing cancer in her lifetime.

What are the side effects of cancer drugs?

Chemotherapy side effects – 

• Weakness
• Nausea
• Vomiting
• Hair loss
• Mouth ulcers
• Neuropathy
• Cognitive side effects

Targeted therapy side effects – 

• Severe skin reaction
• Diarrhea
• Elevated liver enzymes

Hormone therapy side effects – 

• Hot flashes
• Night sweats
• Bone thinning

Which is the oncology medicine manufacturer in India?

Manufacturing world-standard drugs, Aprazer Healthcare is a global oncology brand.

We are the largest generic drug manufacturer and a certified pharmaceutical exporter from India.

We supply an extensive range of oncology orals and oncology injectables to leading countries.

Meeting the global oncology medicine demand, we are trusted across governments worldwide.