High blood pressure is one of the primary factor that contributes to a global rise in heart diseases. High BP does not show early signs. High blood pressure affects various body organs- the kidneys, eyes, and also the brain.

What is High Blood Pressure?

High blood pressure occurs when the flow of blood increases the thrust against the walls.

Blood Pressure is Calculated in Two Ways

Systolic Blood Pressure – It is the pressure of the blood measured when the heart pumps the blood.

Diastolic Blood Pressure – It is the pressure of the blood when the heart relaxes.

The Normal Blood Pressure Range

The healthy and regular blood pressure is 120/80mmHg.

BP beyond 129 /89 is hypertension.

Further increase in blood pressure leads to a BP crisis.

High BP Symptoms

High blood pressure does not cause symptoms or signs that are checked or verified.

It is called a silent killer because most of the time, people get to know the elevated blood pressure until severe consequences or damage have occurred.

The symptoms of chronic rise in BP or the long-term effects may include a few indications, but these are not certain indicators.

• • Headache
• • Dizziness
• • Nose bleed
• • Irregular heartbeat

Uncontrolled Blood Pressure Causes

Uncontrolled or unchecked blood pressure affects body organs, causes renal damage, heart damage, and affects eyesight.

Cardiovascular Damage

• • It affects the pumping of the heart, increasing the force on the heart.
• • It causes wear and tear of blood vessels in the arteries.
• • It causes blood vessels to thicken and reduce blood flow.
• • It causes irregular heartbeats.

Damages Blood Vessels

• • High blood pressure increases the risk of bursting of the vessels or a stroke in the brain.
• • It causes the formation of a bulge in the blood vessels to smooth the high-pressure flow.
• • It affects the arteries in the limbs.

Effect on the Kidney

High BP affects renal blood supply.

• • It damages renal blood vessels, causes them to constrict.
• • It harms the glomeruli and the nephrons.
• • It causes fluid retention.
• • It reduces kidney filtration.

Decrease in Sexual Activity

It reduces the blood flow to muscles and causes sexual decline.

Loss of Vision

High BP bursts the blood vessels in the eye.

Lifestyle Factors That Increase BP

Lifestyle factors significantly affect blood pressure. It includes all the dietary effects and the regular habits.

Unhealthy Diet

• • Processed food with high salt content increases blood pressure.
• • Overuse of Trans and fried diets.

Lack of Physical Activity

The lack of physical activity or long-term sitting, getting overweight, increases strain on the heart. It causes to increase in blood pressure.

Use of Drugs

Tobacco habit induces damage to the lining of the blood vessels, and alcohol use causes to rise in blood pressure by changing hormones.

Stress and Poor Sleep

Stress leads to increased heart rhythm, and poor sleep causes to disrupts hormonal balance.

The Ways to Control Excess Blood Pressure

Maintaining high blood pressure is a journey. Merely depending upon medicines cannot bring desirable outcomes.

The lifestyle factors like diet, regular physical activity significantly help control blood pressure.

Depending upon the severity of the disease, various drug combinations are recommended.

• • Healthy diet – Eating a nutrition-rich diet, fiber can significantly lower high blood pressure up to 11mmhg.
• • Reducing Sodium Intake – Reducing sodium intake from the diet can affect blood pressure by 5-6mmhg.
• • Quitting smoking and alcohol – Quitting smoking and alcohol can reduce high blood pressure by 4 mmHg.
• • Losing weight – For every 1kg of weight loss, the blood pressure reduces by 1mmhg.
• • Regular Exercise – The active lifestyle helps maintain high blood pressure and lowers it to 5-8mmhg.

The Medicines for High Blood Pressure

The minor elevation in blood pressure, i.e., 129/80 mmHg, can be controlled by modifiable lifestyle risks. However, a severe rise in BP above the standard levels needs to involve medication.

• • Hydrochlorothiazide
• • Chlorthalidone
• • Ramipril
• • Losartan
• • Verapamil
• • Metoprolol

Aprazer Healthcare – The Leading Anti-hypertensive Medicine Manufacturer

Aprazer Healthcare, with its significant global presence, is the leading antihypertensive manufacturer and exporter. We manufacture an extensive range of generic antihypertensive medicines, Angiotensin inhibitors and blockers, diuretics, and calcium channel blockers.

We are the top exporters of losartan in Southeast Asia, Africa, and South America.

PAH is the rise of blood pressure in the lungs. A long-term rise in pulmonary BP affects several other organs, including the heart, liver, and kidneys.

Pulmonary Arterial Hypertension?

It is an increase in the blood pressure in the lungs. The pulmonary arteries in the lungs get blocked and obstruct the blood flow. The passage of the blood vessels narrows or gets thinner.

It is the obstructed blood flow to the right side of the heart, affecting the right side at first.

Pulmonary Arterial Hypertension symptoms

• • Shortness of breath
• • Bluish coloration of fingertips or lips
• • Pressure and pain in the chest
• • Weakness
• • Palpitations
• • Dizziness
• • Fluid retention and swelling

What is Idiosyncratic Pulmonary Arterial Hypertension?

The damage to the arterial blood vessels is not caused by a family history or any chronic issue. It is a rare form causing High blood pressure in the lungs due to an unknown cause.

The Causes of Pulmonary Arterial Hypertension

• • Congenital heart disease.
• • Family history of PAH.
• • Respiratory diseases
• • Blood clots in the lungs
• • Immune disorders
• • Severe liver disease
• • Sickle cell anemia
• • Excessive weight
• • Sleep Apnea
• • left side lung disease
• • use of illicit drugs
• • Disorders of the connective tissue
• • Living at height- mountains, hills

Bosenzer (Bosentan) by Aprazer Healthcare

Bosenzer is worldwide available and highly prescribed as an anti-hypertensive treatment for pulmonary arterial hypertension.

• • It improves exercise capacity
• • Slows disease progression
• • Prevent ulcers in the digits – hands and toes
• • Reduces chest pain
• • Improves breathing
• • Improves blood flow to the lungs.

Aprazer Healthcare – Specializes in Specialty Medicines

Aprazer Healthcare is the top global pharmaceutical company, consistently ranking as the world’s largest pharmaceutical manufacturer and exporter. With an extensive product portfolio, we specialize in specialty care medicines, generics, and branded generics. We are committed to high-quality manufacturing supported by WHO-GMP certified manufacturing facilities, stringent quality controls, and regulatory adherence. With global presence and remarkable leadership in pharmaceutical manufacturing, we are the trusted life-saving medicine exporter to 50+ countries.

Working of Bosenzer (Bosentan)

Bosentan is a cholinergic agonist, and it works by blocking endothelin-1, which causes narrowing of the blood vessels. It dilates and relaxes the blood vessels, smoothening the blood flow to the heart.

Common side effects of Bosenzer (Bosentan)

• • Infections of the upper respiratory tract
• • Headache
• • Fluid –retention
• • Low blood count
• • dizziness
• • hypotension
• • joint pain

Precautions and Warnings

Bosenstan can cause severe liver injury and to be avoided in pregnancy due to its teratogenic effects. Effective contraception should be maintained during the course of the treatment, and long-term use may cause a lowering of the sperm count in men.

Conclusion

Bosenzer (Bosenten) is a prescribed medicine and widely used as a primary treatment for pulmonary hypertension.

Bosenzer is available worldwide, and Aprazer Healthcare is the leading Bosentan manufacturer and exporter.

Urinary retention or the loss of urination is a common condition caused by surgical treatment. It is an acute form of urine retention, causing severe complications.

What is Post-Operative Urinary Retention?

It is a condition in which a person is unable to pass urine, even after the bladder has been full. It is usually caused after surgery due to muscular atony caused by anesthesia or an underlying medical condition.

What is Post-Partum Urinary Retention?

It occurs in women after childbirth due to atony of the pelvic muscles. It includes various factors like cesarean, delayed labor, pelvic floor muscle trauma, nerve injury, and anesthesia.

What Causes an Inability to Urinate After Surgery?

• • Medicines – It includes the medications used in surgery, like the anesthetics, which reduce muscular reflex or contraction. The heavy painkillers like morphine or opioid derivatives cause numbness and reduce muscular sensation in the bladder.
• • Abdominal Surgery – The surgery in the lower abdomen or the pelvic area causes local trauma affecting the nerves or some tissue injury.
• • Physical Obstruction – It is the obstruction in the flow of the urine caused by pressure or constriction of the urinary tube due to an enlarged prostate or stones.
• • Medical Conditions – Chronic illnesses cause muscle weakening or nerve damage, which increases the risk of urinary retention.
• • Surgical Pain or Inflammation – Severe pain or the inflammation caused after surgery increases blockade by secretion or spasm.
• • Large Volumes of Intravenous Fluid – Administration of large volumes of fluid leads to stretching of the detrusor muscle of the bladder.
• • Growing Age – With age, the muscular reflexes reduce and increase the risk of urinary retention.

Symptoms of Urinary Retention

• • Severe pain in the abdomen due to pressure built up in the bladder.
• • Complete loss of urination.

The Widely Used Medication to Relieve Post-Operative Urinary Retention

Bethkast (Bethanechol Chloride) by Aprazer Healthcare

It is a cholinergic agent and is widely used to treat urinary retention caused after surgery due to muscular atony or weakness. It is best used to relieve postpartum urinary loss. It stimulates the bladder muscles and restores bladder contraction.

Why Bethkast (Bethanechol Chloride) from Aprazer?

Aprazer Healthcare has positioned itself as the leading pharmaceutical manufacturer, developing top-quality and affordable generics available globally.

At Aprazer Healthcare, supported by world-class manufacturing infrastructure, leveraging cutting-edge technology, WHO-GMP, EU-GMP certified facilities, we manufacture large volumes of quality life-saving medicines.

Aprazer Healthcare, with extensive global networks, regulatory agility, and a robust supply chain, raises the bar as the leading pharmaceutical exporter.

Physical Method to Relieve Urinary Retention

Draining Method – In this, the catheter is used externally to drain the urine accumulated in the bladder. It immediately releases the pain and the bladder pressure.

Complications Caused by Urinary Retention

• • Infections of the Urinary Tract – The accumulation of urine causes a buildup of toxins and harmful bacteria in the bladder, causing a way to infection.
• • Bladder Muscle Damage – The long-term stretching of the bladder causes wear and tear of the bladder muscle.
• • Bladder Stones – The concentrated urine in the bladder leads to the accumulation of various ions that crystallize to form stones.
• • High BP and Kidney Damage – The urine moves to the kidney laden with toxins, increasing the pressure on the kidney, and can also cause kidney damage.

The organ for longevity is not the heart or the brain; it’s the pancreas that helps digestion, provides energy, and manages metabolic and hormonal balances. The rising incidence of pancreatic diseases and cancer raises a serious concern.

What is Pancreatic Cancer?

It is the cancer that occurs in the cells of the pancreas. The pancreatic cancer starts from the duct. The pancreas is the organ that lies in the abdomen, near the stomach.

The Functions of the Pancreas Include:

• • Digestion of food
• • Regulate blood sugar levels.

What Are the Types of Pancreatic Cancer?

Exocrine Cancer – It is a type of cancer that is formed on the internal surface of the duct. It may also be caused in the cells that produce digestive enzymes.

Neuro-endocrine Cancer – It is a hormonal cancer that occurs in the hormone-producing cells of the pancreas. It mainly occurs in the Islets of Langerhans.

Symptoms of Pancreatic Cancer

• • Pain in the upper abdomen
• • Unusual weight loss
• • Back pain
• • Jaundice
• • Nausea
• • Bowel changes
• • Skin rashes
• • Diabetes onset
• • Blood clot

The Risk Factors of Pancreatic Cancer

Smoking – The cigarette contains carcinogens that cause cancer or irritate the pancreatic cell lining.

Obesity – The extra body fat increases the amount of cholesterol, which disrupts the functioning of the organs.

Sudden Diabetes – Any tumor caused in the pancreas may interfere with insulin production.

Exposure to Hazardous Chemicals – The harmful chemicals, like dyes, pesticides, etc., cause DNA damage.

Chronic Pancreatitis – Inflammation caused by various diseases of the pancreas, caused by alcohol use, gallstones, or genetic stones.

What is the Treatment of Pancreatic Cancer?

• Surgery: It is the process in which the head of the pancreas is removed. It may also involve the removal of part of the small intestine and the bile duct.
• Chemotherapy: It is the use of chemotherapy drugs to kill cancer cells. Chemotherapy is given as the first treatment to shrink the tumor or after the surgery.
• Radiation Therapy: These are the high-energy radiations that are used to shrink the cancer tumor before and after the surgery.
• Targeted Therapy: These are the drugs that inhibit specific proteins and enzymes in the cancer cells.
• Immunotherapy: In this, the T-cell activity is enhanced by using antibodies, etc.

What Are the Medicines for Pancreatic Cancer?

• • Apragem – Gemcitabine
• • Albumin-bound paclitaxel (Nab-paclikast)
• • Capecitabine – Capekast

Platinum Drugs:

• • Cisplatin – Cycokast
• • Oxaliplatin – Oxazer

Aprazer Healthcare Leads in Oncology Care

Aprazer Healthcare, as the leading oncology drug manufacturer, develops a range of WHO-GMP-certified anticancer drugs. Developing more than 30 generic drugs, we are the leading exporter of anticancer medicines worldwide.

• • WHO-GMP certified medicines
• • Assured quality and safety
• • Continuous research and drug development
• • Advanced oncology care medicines
• • Global availability

Watery stool or diarrhea occurs as a common symptom of any GIT disturbance. It signifies many underlying conditions, including IBS, SIBO, etc. However, traveler’s diarrhea is an infectious condition. Mild diarrhea gets cured by itself, but long–term infection needs an antibiotic treatment.

What is Traveler’s Diarrhea?

It is a common condition that occurs when you ingest contaminated food or water while traveling from one place to another.

Traveler’s Diarrhea Symptoms-

• • Diarrhea
• • Abdominal Cramps and Bloating
• • Nausea
• • Vomiting
• • Urgency to defecate

Severe Symptoms

• • High fever
• • Dehydration
• • Stomach pain
• • Rectal pain
• • Blood in the stool
• • Continuous vomiting

Causes of Traveler’s Diarrhea

Various infections caused by bacteria, protozoa, or viruses lead to stomach upset, causing GIT distress.

• Food – Eating uncooked food, unwashed or unpeeled fruits.
• Water – Drinking untreated water from taps.
• Other reasons – Unwashed hands, contaminated food at restaurants, street food, etc.

Risk Factors for Developing Diarrhea

• • Young Adults – It is common in young people with low levels of acquired immunity, and they are less cautious about using things.
• • Weakened Immune System – People having chronic diseases or who take medications that suppress the immune system it increases vulnerable to infections.
• • Medical Conditions – Underlying conditions like diabetes, heart issues, etc., that lower immunity, and gastric conditions like IBS, all of them increase the risk of infection.
• • Travel in Moist Climates – Travel during the hot season or during the monsoon increases the risk of infection. The germs survive well in hot, humid conditions.
• • Use of Medications – The long–term use of antacids or acid blockers makes the stomach PH acidic enough for germs to survive.

Steps to Prevent an Infection-

• • Washing hands regularly
• • Eating freshly cooked meals
• • Unpeeled fruits and raw salads
• • Use purified water for ingestion.
• • Maintain Hydration
• • Avoid raw or uncooked meat or fish
• • Avoid stale foods
• • Avoid ice made from tap water.

What to do in Diarrhea?

Dehydration – It is the most crucial condition developed by persistent watery stools. The severe loss of electrolytes leads to an imbalance and affects various internal organs.

• • Drink electrolyte-based fluids.
• • Avoid a high fiber or fat diet.
• • Use an OTC antidiarrheal.

If the diarrhea persists longer, it may need further medications.

The best Antibiotic Used for Gastrointestinal Infections

Rifaxigem (Rifaximine) – It is a broad-spectrum- spectrum antibiotic, used against many types of bacteria that cause infections in the stomach. It is widely used to treat E.Coli infections, SIBO, IBS with diarrhea, and hepatic encephalopathy.

Benefits of Rifaxigem

• • Due to local action, it has low systemic absorption.
• • Broad scale of activity
• • It does not affect the gut flora
• • Better tolerated
• • Low risk of antibiotic resistance

Aprazer – Top Quality Gastrointestinal Medicines from Leading Manufacturer

Aprazer Healthcare leads the way in manufacturing gastrointestinal products, premium quality antibiotics, and hepatoprotectives.

Aprazer is a name built on trust and quality. As the leading gastroenterology medicine manufacturer, with WHO-GMP certified manufacturing facilities, using high-quality API, we produce a range of world-standard generic gastrointestinal medicines.

The products manufactured by Aprazer are accepted and trusted by the leading healthcare professionals and the patients worldwide.

We strive to innovate and develop new drug molecules to improve patient outcomes and make a difference in the lives of, who suffer from GIT diseases.

We are focused on developing innovative anticancer medicines, uniting science, technology, and talent to get ahead of the disease. Impacting a million lives in Kenya, we are the leading anticancer manufacturer and exporter in Nairobi, delivering global-standard, affordable anticancer medicines.

Top-Tier Anticancer Medicine Manufacturer from India to Nairobi

With a mission to provide equitable access to essential healthcare in Nairobi, we manufacture a range of generic equivalents with uncompromised quality and efficacy. With stringent quality controls and adherence to global regulatory standards, we develop anticancer medicines that are acceptable in Kenya.

• • WHO-GMP certified medicines
• • Affordable anticancer generic drugs
• • Worldwide availability
• • Advanced care anticancer drugs
• • Strong logistic partners
• • Safe and effective products
• • Adherence to global standard quality.

Trusted Anticancer Medicine Exporter, Nairobi, Kenya

As the leading pharmaceutical manufacturer and exporter to Kenya, Aprazer Healthcare significantly contributes to the Kenyan healthcare system. Partnering with the leading hospitals, clinics, and government initiatives, we offer an affordable range of anticancer drugs in Nairobi.

• • Regulatory Compliance with Kenya – Leveraging global quality standards and country-specific approvals, we strictly adhere to global regulatory standards and good distribution practices in Nairobi, Kenya.
• • Integrated Supply Chain and Logistics – With our strong logistic support, implementing technological advancements, we ensure temperature-controlled storage and handling throughout the supply chain.
• • Stronger Partnerships and Market Access – Partnering with the distributors, suppliers across Kenya, we are committed to making advanced oncology treatment drugs affordable and accessible to all.
• • Transparent Communication – With strong customer care support services and responsiveness, we ensure partner satisfaction and long-term relationships.

Aprazer Healthcare – Bringing World-class Anticancer Treatment to Emerging Markets

Addressing the growing demand for cancer medicines, Aprazer Healthcare is the force behind the availability of the widest anticancer range in Nairobi, Kenya.

• • Chemotherapy Anticancer Drugs
• • Hormonal Therapy Anticancer Drugs
• • Targeted Therapy Anticancer Drugs

Top Choice for Kenya’s Pharmaceutical Importers – Aprazer Healthcare

We work in the best interest of the stakeholders and build long-term relationships. Our core values include –

• • Transparent dealing
• • Consistent quality
• • Regulatory compliance and flexibility
• • Timely response
• • Uninterrupted supply chain

Top-Quality Anticancer Medicines in Nairobi, Manufactured by Aprazer Healthcare

With a patient-centric approach, Aprazer Healthcare develops drugs targeting the leading cancers to meet patients’ needs in Nairobi.

• • Abirakast (Abiraterone acetate) – Widely used in prostate cancer that develops resistance to androgen therapy.
• • Indenza (Enzalutamide) – The next-generation drug, highly effective against prostate cancer that is not responding to androgen therapy.
• • Inlybest (Axitinib) – Targeted therapy drug used in advanced-stage kidney cancers.
• • Lenvakast (Lenvatinib) – Widely used in radioactive iodine-refractory differentiated thyroid cancer.

Working with the local partners, we strive to make essential medicines accessible to the Kenyan population.

Aprazer Healthcare is at the forefront of manufacturing next-generation anticancer medicines through relentless innovation and making them accessible worldwide.
As the leading anticancer drug manufacturer and exporter to Ghana, we are committed to manufacturing world-standard, high-quality anticancer medicines. Leveraging cutting-edge technology and stringent quality controls, we develop safe, efficient, standard anticancer products.

Leading Anticancer Medicine Exporter to Ghana

With our world-class manufacturing infrastructure and our commitment to excellence and innovation, we are the trusted healthcare partners in Ghana, partnering with the leading hospitals, healthcare institutes, government medical centers, and NGO’s in Ghana.

With our focus on developing new drug delivery systems and advanced drug molecules, Aprazer Healthcare makes a significant contribution to improving patient outcomes.
We strive to make essential healthcare affordable and accessible to Ghanaian people.

Why Aprazer Healthcare is the Trusted Healthcare Partner in Ghana?

Changing the challenging status quo in cancer care in Ghana, we are the top manufacturers exporting a range of pharmaceuticals in Ghana.

• • WHO-GMP certified medicines
• • Affordable anticancer generic drugs
• • worldwide availability
• • Advanced care anticancer drugs
• • Strong logistic partners
• • Safe and effective products
• • Adherence to global standard quality.

Featured Products

Indenza (Enzalutamide)

Lenvakast (Lenvatinib)

Sorafekast (Sorafenib)

Lapakast (Lapatinib)

Nab-Paclikast (Albumin-bound Paclitaxel)

Zoldokast (Zoledronic Acid)

Abirakast (Abiraterone Acetate)

Paclikast 260mg Injection

Aprazer Healthcare – Top-Notch Pharmaceutical Manufacturer from India

We lead the way in manufacturing oncology treatments and medicines for various cancers and solid tumors.
With stringent quality controls and effective measures, we ensure unbeatable quality products.

• • Global standard manufacturing facilities and accreditations.
• • Good Manufacturing Practices (GMP)
• • Good clinical practices
• • leveraging cutting-edge technology
• • Quality Management Systems
• • Strict adherence to the Regulatory framework in Ghana

Aprazer Healthcare – Anticancer Portfolio for Ghana

We manufacture the advanced oncology therapy drugs and are the leading exporter to Ghana.

• • Chemotherapy drugs – Apihydro (Hydroxyurea ), Cabozer (Cabozantinib ), Acalakast (Acalabrutinib )
• • Hormone therapy drugs – Indenza(Enzalutamide) , Abirakast (Abiratone acetate)
• • Targeted therapy drugs – Lenvakast ( Lenvatinib ) , Lapakast ( Lapatinib )

Top Anticancer Injection Manufacturer and Exporter to Ghana

With stringent quality controls and adherence to aseptic manufacturing and packaging, Aprazer Healthcare develops a wide range of sterile anticancer injections and exports top–quality anticancer injections to Ghana.

• • Fulvekast (Fulvestrant ) – Prefilled syringes for ease and convenient use.
• • Nab- Paclikast – Albumin-bound paclitaxel to facilitate better absorption and improve patient outcome.

Aprazer Healthcare is expanding its broad, deep pipeline, accelerating advancements to deliver transformative anticancer solutions in Ghana.

What is the Targeted Therapy Approach in Cancer?

Targeted therapy is a cancer care treatment in which the anticancer medicines are used to target exclusively the cancer cells, inhibiting the specific enzymes or proteins involved in cancer cell proliferation.

Working of Targeted Therapy in Cancer Treatment

Unlike the chemotherapy treatments, which indiscriminately harm the normal, healthy cells, the targeted therapy drugs bind to specific molecules, inhibiting only the cancer cells.

Blocking the Cancer Cell Signaling

The cancer cells in the body continue to grow and proliferate, receiving signals from the intracellular pathways. The targeted therapy drug molecules inhibit these signaling pathways and stop cancer cell multiplication or replication.

Inhibit New Blood Vessel Formation

The tumors or the cancer cells generate new blood vessels to grow in size and number. These blood vessels carry oxygen and essential nutrients for cancer cell proliferation.

The targeted therapy medicines inhibit the formation of new blood vessels or destroy the newly developed blood vessels, which leads to cell starvation and death due to deprivation of oxygen and essential nutrients.

Programmed Cell Death – The normal cells in the body grow and die in a sequenced manner. The cancer cells escape the death process. The targeted therapy drugs process the cancer cell to undergo the natural cell death process.

Inhibiting DNA Repair Mechanisms – The cells undergo a process of cell metabolism and DNA repair. The targeted anticancer drug inhibits cancer cell repair mechanisms, thus blocking the synthesis.

Delivering Toxins Into the Cancer Cells – The monoclonal antibodies or certain drugs carry toxic elements and bind to the cancer cell surface. They release toxic substances into the cancer cell, which causes cancer cell death.

Activates the Immune System – The drugs attach to the cancer cell receptors. The cancer cells are then targeted by the immune system.

Inhibiting Specific Hormones – These are the hormone therapy drugs that inhibit the growth of hormone-sensitive tumors or cancers. These drugs inhibit specific hormones essential for tumor growth and division, causing cancer cell death. These are widely used in breast cancer and prostate cancer therapies.

Benefits of Targeted Cancer Therapy

• • Precision and Specificity – Targeting the specific cancer cells, it offers less damage to the healthy or normal cells.
• • Fewer Side Effects – Due to their selective nature, the targeted therapy drugs do not harm the normal cells and offer fewer side effects, like less hair loss or bone marrow suppression.
• • Decreased Resistance – The cancer cells strive to develop, forming new pathways, and the targeted drug therapies selectively inhibit alternative pathways, causing cancer cell death.
• • Increased Effectiveness – Due to specific targeting, they are more effective in controlling cancer cell growth and spread.
• • Better Tolerance – High selectivity and lesser side effects lead to better tolerance. It allows patients to maintain physical activity and functions.

Cancers That Respond Best to Targeted Therapy

• • Breast cancer
• • Lung cancer
• • Colorectal cancer
• • Prostate cancer
• • Melanoma
• • Blood cancer
• • Kidney cancer
• • Thyroid cancer
• • Bladder cancer

The Common Side Effects of Targeted Therapy

• • Fatigue
• • Skin rash
• • Dry skin
• • Diarrhea
• • Nausea
• • High blood pressure
• • Liver dysfunctions

Rare but serious side effects include:

• • Cardiac problems
• • Lung inflammation
• • Blood clotting issues

The Innovative Targeted Therapy Medicines by Aprazer

Aprazer Healthcare advances cancer care treatment, manufactures world-standard targeted therapy anticancer drugs that offer precision care and selective action.

Tyrosine Kinase Inhibitors (TKIs) – They work by inhibiting the cancer cell cycle, interrupting cell signals.

• • Lenvakast ( Lenvatinib ) – Liver, thyroid, and renal cancer.
• • Imatikast ( Imatinib ) – Used in stomach cancer and chronic leukemia.
• • Lapakast ( Lapatinib ) – It is widely used for HER-2 positive breast cancer and lung cancer.
• • Sorafekast ( Sorafenib ) – Used for hepatic cancer, renal cancer, and throat cancer.

PARP Inhibitors – Inhibit DNA repair mechanisms

• • Olabir (Olaparib) – Used for breast cancer, ovarian cancer, and prostate cancer.

Angiogenesis Inhibitors– Inhibit new blood vessel formation

• • Sutekast (Sunitinib)- Used in renal cancer and stomach cancer.
• • Pazokast (Pazopanib)- Kidney cancer and soft tissue sarcomas

Androgen Receptor Inhibitors – They inhibit the androgen receptor, which produces testosterone that promotes tumor growth.

• • Indenza (Enzalutamide) – Used in resistant prostate cancer (CRPC).
• • Abirakast (Abiraterone) – Used in advanced prostate cancers.

Aromatase Inhibitors- These reduce the production of estrogen, which is effective in hormone-sensitive breast cancer.

• • Anzakast (Anastrozole) – Used in breast cancer in elderly women.
• • Letrakast (Letrozole) – Widely prescribed for hormone receptor-positive breast cancer.

Estrogen Receptor Antagonist 

• • Fulvekast (Fulvestrant) – Widely used for advanced breast cancer and hormone–receptor positive breast cancer.

Aprazer Healthcare, dedicated to equitable access to essential healthcare for everyone, is the leading exporter of anticancer medicines, supplying globally.

• • WHO-GMP certified medicines
• • Continuous research and drug development
• • Leveraging cutting-edge technology
• • Assured quality and safety

Aprazer Healthcare, the leading anticancer medicine manufacturer, is the top pharmaceutical company from India, manufacturing the latest advanced anticancer drugs and innovative therapies that bring better patient outcomes and enhance survival.

Through scientific innovation, continuous research, and drug development, Aprazer stands as the leading anticancer medicine manufacturer in India. We aim to manufacture advanced Life-saving medicines that transform health outcomes and accelerate India’s leadership as the largest global pharmacy.

With our collaborative approach and purpose-led partnerships with hospitals, government medical centers, NGOs, and clinics, we aim to deliver global-standard anticancer medicines, affordable and accessible worldwide.

Addressing the healthcare challenges in cancer treatment and reaching out to the remote demographic areas, we aim to deliver affordable anticancer medicines at the time of greatest need.

Focusing on the rising health concerns, chronic diseases, and critical illnesses, we manufacture a range of quality-driven HIV medicines, critical care medicines, and anticancer medicines.

What makes Aprazer Healthcare the leading Anticancer Medicine Manufacturer in India?

Global Standard Manufacturing – With WHO-GMP certified manufacturing facilities, we strictly adhere to the highest quality standards and controls to develop world-class, quality-efficient medicines.

Innovation – With world manufacturing infrastructure, leveraging cutting–edge technology, Aprazer Healthcare continues to invest in research and new drug development. We develop advanced and the latest oncology care medicines.

Extensive Product Portfolio – Developing more than 30+ anticancer drug molecules, we offer the largest range of advanced anticancer drugs, including chemotherapy, targeted therapy, and hormonal therapy drugs.

Affordability – Streamlining the manufacturing process, utilizing cost-efficient techniques and automatically controlled mechanisms, we strive to minimize wastage and reduce the cost.

We develop the largest range of generic anticancer drugs and biosimilars with guaranteed quality and safety to ensure affordable access to life-saving medicines.

Advanced Technological Integration

With continuous advances in manufacturing techniques, we leverage streamlined processes like continuous batch manufacturing to ensure consistent quality, reducing production time and manufacturing large quantities.

Sterile Manufacturing Practices

As the leading anticancer injection manufacturer in India, we adhere to sterile, aseptic conditions, using the advanced isolator technology to develop safe, sterile injections.

Global Reach

With a mission to achieve global health equity and to make advanced healthcare treatment accessible across the globe, we are the leading anticancer medicine exporter to countries in South Africa, Southeast Asia, South America, and the Commonwealth countries.

Advanced Drug Delivery Systems

We are capable of manufacturing the novel drug dosage forms ranging from tablets, capsules, to prefilled syringes. We specialize in manufacturing lyophilized powders, ready-to-use injections, IV infusions, single-use vials, Nanoparticle formulations, etc.

Why choose Aprazer Healthcare?

• • WHO-GMP certified medicines.
• • Scientifically backed solutions
• • Assured quality and efficacy
• • Stringent quality controls and audits
• • Affordable generic anticancer medicines
• • Advanced therapy medicines

Recognized as the leading pharmaceutical company in India, known for its low-cost generic anticancer drugs, Aprazer holds a significant share in the anticancer drug manufacturing and global export from India.

Aprazer Healthcare leads the way in developing a wide range of advanced anticancer medicines, affordable generics, accessible to all.

Understanding the global cause and the need for critical care, Aprazer Health Care is the leading anticancer drug manufacturer in India.

Exporting the latest anticancer medicines to countries in South Africa and America, Commonwealth countries and Southeast Asia, Aprazer stands as the leading global anticancer medicine exporter.

The Anticancer Medicines Manufactured By Aprazer Healthcare

Our Extensive Product Portfolio includes chemotherapy, targeted therapy, and Hormonal therapy medicines.

Chemotherapy

These are the anticancer medicines that are cytotoxic in nature. They kill the cancer cells or inhibit their growth and proliferation by interrupting the cell cycle through different mechanisms. They are non-selective in nature and affect all types of body cells. It is usually called systemic chemotherapy.

The Top Anticancer Medicines Prescribed Globally (Chemotherapy)

• • Carbokast (Carboplatin) – Approved for ovarian cancer and used in non-small lung cancer, head and neck cancer.
• • Cycokast (Cisplatin) – Widely used in ovarian cancer, bladder cancer, and testicular cancer.
• • Temzokey (Temozolomide) – Accepted and widely used for brain cancer.
• • Capekast (Capecitabine) – Used for colon, breast, and stomach cancer.
• • Cytarzer (Cytarabine) – It is used for all types of blood cancers.
• • Apragem (Gemcitabine) – Used for pancreatic, ovarian, and bladder cancers.
• • Trexazer (Methotrexate) – Used for breast cancer, blood cancer, throat cancer, arthritis, and psoriasis.
• • Dorucin (Doxorubicin) – Used against lung cancer, blood cancer, and HIV induced cancers.
• • Daunozer (Daunorubicin) – It is used for various types of blood cancer.
• • Paclikast (Paclitaxel) – Used in lung cancer, cancer of the ovaries, and the breast.
• • Docekast (Docetaxel) – Prostate cancer, breast cancer, Head and neck cancers.
• • Posiact (Etoposide) – Used in testicular cancer, bladder cancer, and lung cancer.

Targeted Therapy

These are the advanced anticancer medicines that are selective in their action. The targeted therapy drugs act directly upon the cancer cells and proteins, inhibiting cell proliferation and growth. They do not affect the healthy cells and exhibit minimal side effects.

Top Anticancer (Targeted Therapy) Medicines

• • Lenvakast (Lenvatinib) – It is widely used in hepatocellular, thyroid or the renal cancer.
• • Imatikast (Imatinib) – Used in GIT tumors and Chronic leukemia.
• • Lapakast (Lapatinib) – It is widely used for HER-2 positive breast cancer and lung cancer.
• • Sorafekast (Sorafenib) – For liver cancer, kidney cancer, and thyroid cancer.
• • Olabir (Olaparib) – Used for breast cancer, ovarian cancer, and prostate cancer.
• • Sutekast (Sunitinib) – Used in kidney cancer, pancreatic cancer, and gastrointestinal cancer.
• • Pazokast (Pazopanib) – Kidney cancer and soft tissue sarcomas.

Hormonal Therapy

These are the anticancer drugs that inhibit hormonal secretion and are effective against hormone-sensitive cancers. They stop the hormonal supply to the cancer cells.

Ovarian cancer, breast cancer, prostate cancer, and other reproductive system cancers are treated by hormonal therapy. It is also used in bladder cancer, thyroid cancer, and uterine cancer.

The Top Anticancer (Hormone Therapy) Medicines

• • Indenza (Enzalutamide) – Approved for castration resistant prostate cancer.
• • Abirakast (Abiraterone) – Effective in advanced-stage prostate cancer.
• • Anzakast (Anastrozole) – Used in breast cancer in elderly women (post-menopausal).
• • Letrakast (Letrozole) – Widely prescribed for hormone receptor-positive breast cancer.
• • Fulvekast (Fulvestrant) – Widely used for advanced-stage breast cancer.

Aprazer Healthcare – Global Standards of Quality and Safety

Aprazer Healthcare, a top-tier anticancer medicine manufacturer from India, assures the Global Standards of Quality and Safety.

Aprazer is a globally recognized name, manufacturing a wide range of generic anticancer drugs for affordable access. Leveraging cutting-edge technology, Aprazer develops the latest advanced oncology formulations and is at the forefront of new drug discovery and drug development.

Present globally, Aprazer Healthcare makes a significant contribution to global access to advanced, affordable anticancer solutions.

• • WHO-GMP certified manufacturing facilities
• • Continuous research and drug development
• • Cost-effective production processes
• • Adherence to Stringent Quality Controls
• • Worldwide availability
• • Leading Anticancer medicine exporter from India