WHO establishes stringent parameters for manufacturing oncology medicines.

The anti-cancer drugs are highly toxic, potent medicines.

They are developed in controlled environments with safety parameters.

Facility design/containment systems – 

Dedicated facilities- 

These are separate blocks or rooms for manufacturing toxic drugs.

Dedicated blocks for multi-step processes like granulation, blending, and tableting.

• Segregated material flow
• Restricted access barrier system
• Air-lock systems between multi-chamber rooms.
• Air-tight architecture, sealed floors and roof

Air conditioning systems (HVAC) – 

It is used for clean room standardization and environmental isolation.

• Maintaining pressure variants in toxic zones.
• HEPA filters for air filtration.
• Unidirectional airflow
• Temperature and humidity control

 Personnel Safety – 

The anticancer drugs are highly toxic and irreversibly damage living tissue.

The manufacturers must ensure high safety measures for the workers.

Cytotoxic drug handling training must be provided.

• Use of protective gear /garments
• Air borne drug /particulate matter monitoring.
• Decontamination facilities like dedicated shower or eye wash stations.

Validation process- 

It ensures that each activity and process is under permissible limits.

• Equipment /instrument validation
• Operational validation
• Design validation
• Installation validation
• Performance validation
• Cleaning validation

Waste product management – 

The residue of the oncology drugs is highly toxic.

WHO recommends safe disposal of toxic components.

• Separate in/out bags.
• Chemical treating systems
• Segregation for biological, hazardous, or general waste
• Fumigation exhausts to neutralize toxic vapors.

Why is a stringent regulatory framework required for oncology drug manufacturing?

The manufacturing process of oncology drugs demands high precision and sterility.

These are cytotoxic drugs.

These are lethal and directly kill viable cells.

Requirement for precision- 

They have narrow safety margins.

Large doses damage the organs.

A lowered dose may lead to treatment failure.

Safety of personnel- 

Spilling or touching the drug component may damage human cells.

It can cause serious complications.

Dedicated flow lines- 

This prevents cross-contamination.

A trace of the cytotoxic drug clinging to the pipes may get incorporated into other medicines through the same pipeline.

The Air flow systems- 

Any vapor or fumes of the toxic product in the air may lead to hazardous results when inhaled.

The particulate matter in the air may contaminate other general products.

Which is the leading GMP & GLP certified oncology medicine manufacturer? 

Aprazer Healthcare is an oncology medicine manufacturer.

Globally recognized for manufacturing top quality pharmaceuticals, we are the leading oncology drug exporters.

We are trusted for our commitment to quality (WHO-GMP standards).

We manufacture a wide range of oncology drugs.

Oncology orals/Oncology injectable

Our flagship products include chemotherapy injectables-

• Carboplatin – Carbokast 150 
• Cisplatin – Cycokast -50 
• Cytarabine 500mg – Cytarzer 500 
• Doxorubicin – Dorucin -10 

India is the largest producer of antiviral drugs.It contributes to 22 % of the total supply of generic hepatitis medicines.

Despite the major supply, Hepatitis remains a global health crisis.

Global Burden and Treatment Gap 

• More than 350 million people worldwide suffer from hepatitis infection.
• 1.3 million Deaths occur every year due to the severe lack of testing and treatment access.
• 1.1 million Deaths occur due to cirrhosis caused by untreated Hepatitis B.
• Fewer than 5 % of infected individuals receive the life-saving antiviral treatment.

The common hepatitis drugs exported from India

Hepatitis C medicines exported from India – 

Sofosbuvir + Velpatasvir tablets – Velakast

Daclatasvir and Sofosbuvir Tablets – Sofokast Plus

Ledipasvir & Sofosbuvir Tablets- Ledikast

Daclatasvir Tablets- Dacikast

Ribavirin Capsules- Ribasure

Sofosbuvir Tablets – Sofokast

Hepatitis B medicines exported from India – 

Tenofovir Alafenamide 25 mg tablet- Tafnext

Entecavir 1mg- Entekor-1

Tenofovir Disoproxil Fumarate Tablets- Tudobest

Why Aprazer Healthcare is the leading Hepatitis Medicine Manufacturer/exporter 

World-class infrastructure- 

Equipped with modern equipment and technology, we are capable of manufacturing advanced products.

The advanced manufacturing processes minimize wastage, leading to cost-effective manufacturing.

Regulatory compliance 

Our manufacturing processes strictly adhere to GMP & GLP regulations.

Robust Quality controls 

We adhere to the global standards of manufacturing.

• Stringent quality control protocols
• In–house quality checks and controls
• In-house testing

Strong distribution network 

We are globally present, supplying affordable standard-quality drugs.

• Cold chain delivery systems
• Traceable supply chain
• Authentic logistic support

Robust documentation support

Our team of experts offers end-to-end support in –

• Drug approvals
• CTD dossiers for pharmaceutical importers
• Custom and logistic documents

Extensive product portfolio – 

We specialize in manufacturing antiviral combinations

Our product portfolio comprises a comprehensive range of –

• Hepatitis B medicines
• Hepatitis C medicines

Why is it important to treat Hepatitis timely? 

The delayed /untreated hepatitis infection progresses to irreversible liver damage.

• It leads to liver scarring.
• increases the risk of liver cancer
• Increases the risk of spreading the virus

Which hepatitis infection is curable?

Hepatitis C is highly curable.

It is treated by direct-acting antivirals.

Hepatitis B is not curable.

It is managed and treated by antiviral combinations.

How do hepatitis medicines work? 

Hepatitis C medicines target the proteins required for viral cell multiplication.

It stops cell multiplication, leading to elimination.

Hepatitis B suppresses the virus. It lowers the viral count.

It prevents liver scarring and improves immunity.

What are the hepatitis medicine side effects?

The common side effects include-

• Weakness
• Dizziness
• Headache
• Stomach ache
• Diarrhea
• Insomnia

Treat the lethal virus through the effective solution offered by Aprazer Healthcare. 

Aprazer Healthcare, as the leading ( Hepatology medicine manufacturer) is the trusted hepatitis medicine exporter.

We are the top drug exporters to countries in

Asia, Africa, the Middle East, and America.

Cholesterol is a waxy or fatty fluid in the body.

It is widely utilized to make vitamins and hormones.

• Forms the outer cell wall layer
• Forms hormones like estrogen and testosterone
• Aids digestion
• Protects nerve fibers

The main types of cholesterol- 

• HDL – These are high-density lipoproteins.

It is also called good cholesterol.

It is the clearance of extra cholesterol from the body.

The excess cholesterol is carried in the blood to the liver.

The higher levels indicate the body is clearing lipids.

• LDL: It is also called bad cholesterol.

These are low-density lipoproteins.

This indicates the blood is unable to carry extra cholesterol.

The lipids build up in the arteries.

It increases the risk of heart disease.

• Triglycerides – These are the fat cells in the body.

These store extra energy when the body is unable to burn calories.

The extra calories are stored in the form of triglycerides.

The normal cholesterol ranges- 

• Total cholesterol – Less than 200mg/dl

• LDL – Less than 100mg /dl
• HDL- It must be 60mg/dl or higher
• Triglycerides – It must be less than 150mg/dl

What symptoms must one look for in high cholesterol?

It does not show any physical signs.

The rare symptoms include-

• Yellow patches around the eyes
• Fatty bumps or growths on the skin
• Cholesterol deposition around the iris in the eye.

In the long term, it leads to –

• Chest pain
• Shortness of breath
• Leg pain

Why is HDL good cholesterol? 

HDLs are protective cholesterol.

It eliminates the extra cholesterol from the body.

It carries it to the liver for breakdown.

It is protective in nature.

It prevents blockages in the arteries or heart.

What is the negative effect of cholesterol on the heart? 

Cholesterol harms the body in several ways.

The lipids deposit in the arteries.

It increases the risk of –

• Heart diseases
• Stroke
• Arthrosclerosis

The causes of high cholesterol- 

• High-fat diet
• Family history
• Inactivity
• Chronic stress
• Excessive alcohol /smoking
• Genetics
• Age /sex

The cholesterol-lowering drugs- 

• Statins – This reduces the synthesis of cholesterol in the liver.

Atorvastatin, Rosuvastatin

• Cholesterol absorption inhibitors – 

These inhibit cholesterol absorption in the stomach.

• Bile Acid Sequestrants- These agents bind to cholesterol.

It helps utilize body cholesterol.

• Fibrates- These lower the triglyceride levels.

• PCSK9 Inhibitors- 

These drugs block the proteins that destroy LDL receptors.

The LDL receptors are preserved.

They carry more lipoproteins to the liver.

This leads to clearing more cholesterol from the blood.

Can I lower high cholesterol?

Managing an active lifestyle with proper medication.

• Low-fat diet
• Regular exercise
• Proper medication

Who all must take cholesterol medication?

The cholesterol medicines are prescribed based on future cardiac risks.

Cholesterol drugs are usually given to people with –

• Cardiac disorders
• Extremely high LDL levels
• People with diabetes
• High risk of heart disease in the upcoming 10 years.
• High Blood pressure
• Dangerously high cholesterol
• Family history

Which is the leading third-party lipid-lowering drug manufacturer?

Aprazer Healthcare is a leading third-party manufacturer.

We manufacture a global range of cardiovascular drugs.

Our product portfolio includes –

• Lipid-lowering agents 
• Antihypertensive combinations
• Antilipemic Agents Combination & HMG-CoA Reductase Inhibitors (Statins)

Supplying drugs globally, we are the top drug distributors.

• Global standard manufacturing
• Regulatory compliance
• Robust quality controls
• Strong distribution network
• Trusted partnerships

These are involuntary muscle contractions.

They cause rapid, uncontrolled movements in the body.

Convulsions are common in epilepsy.

The causes of convulsions include –

• Epileptic seizures – Due to changes in electrical signals in the brain.

• Non-epileptic seizures –  These are caused due to psychological illness
• Febrile seizures – These occur in children having high fever.

The common illness with recurrent convulsions- 

Epilepsy: causes and symptoms 

It is a brain dysfunction.

It happens due to abnormal electrical signals in the brain.

It is the recurrence of seizures.

The different types of seizures- 

• Focal seizures- 

When the seizure affects one side of the brain.

• Generalized seizures- 

When the seizure occurs on both sides of the brain.

The common symptoms of Epilepsy- 

• Rigid muscles
• Leg jerking
• Starring spell
• Loss of muscle control
• Repetitive movements
• Loss of bladder functions
• Loss of awareness
• short-term confusion

The causes of epilepsy- 

The abnormal conduction in the brain may lead to twitching or seizures.

The causes include-

• Structural changes in the brain – Any changes in the brain anatomy.

Head injury, trauma, strokes, or tumors.

• Family history /genetics – History of seizures in close relatives and genetics.
• Brain infections- infections like meningitis or abscess in the brain.
• Metabolic dysfunction –Fluctuating sugar or changes in neurotransmitter levels.
• Autoimmune disorders – Like ADHD, autism, etc.

The factors that trigger seizures- 

• Lack of sleep
• Alcohol
• Smoke
• Illicit drug use
• Stress
• Dehydration
• Skipped meals

What are the anti-epileptic drugs?

Sodium channel blockers – Phenytoin, carbamazepine

It inhibits rapid nerve conduction.

It blocks sodium entry.

GABA boosters – clonazepam, lorazepam

GABA is a neurotransmitter that calms nerve activity.

It reduces the rapid nerve firing.

Calcium channel blockers- Ethosuximide

It blocks the calcium channel.

It reduces nerve firing.

GABA/Glutamate modulators- 

These drugs balance the excitatory and the inhibitory chemicals in the brain.

Why is it advised to strictly adhere to anti-epileptic treatment?

It is advised to consistently take epilepsy medicines upon time.

Leaving or altering the dose may cause complications.

• Triggers seizures
• Prolong the length of seizures
• Uncontrolled seizures

What are the side effects of anti-epileptic drugs?

• Sleepiness
• Tiredness
• Stomach upset
• Blurry vision
• Unexpected weight
• Brain fog
• Mood shifts

Severe side effects –

• Severe skin rashes
• Yellowish skin
• Stomach ache
• Unusual bleeding /bruising
• Severe depression

Which is the third-party drug manufacturer of anticonvulsant?

Aprazer Healthcare is the leading pharmaceutical manufacturer.

We manufacture and export a global range of anti-epileptic combinations worldwide.

Accredited and licensed by the global health authorities, our products are trusted and demanded.

We are chosen for our credibility, such as:

• Operational excellence
• Regulatory compliance
• Precision manufacturing
• Advanced infrastructure

Explaining Diabetes- 

It is a chronic condition.

It is a condition in which blood sugar rises exceptionally high.

The body is not able to make insulin or use it in the right way.

• Type 1 Diabetes- 

It is also called childhood diabetes.

The pancreatic cells are unable to produce insulin.

The autoimmune disorder damages the pancreatic cells.

• Type 2 Diabetes – It is a chronic condition.

Unable to utilize insulin, glucose levels build up in the body.

Diabetes symptoms – 

• Frequent urination
• Excessive thirst
• Unusual weight loss
• Increased appetite
• Blurry vision
• Frequent infections

Type-1 diabetes causes- 

The immune system attacks its own body cells.

It is usually –

• Hereditary condition
• Triggered by environmental toxins

Type-2 diabetes causes – 

Insulin resistance-

The body cells are not able to respond to insulin.

Low insulin production – 

The pancreas is unable to produce enough insulin.

The important causes include –

• Family history
• Obesity
• Sedentary lifestyle
• Age above 45 years
• Underlying health conditions

Type 2 diabetes drugs – 

Biguanides- Metformin

GLP-1 Receptor Agonists- 

Semaglutide, Tirzepatide 

SGLT2 Inhibitors- 

Dapagliflozin, empagliflozin

Sulfonylureas- Glipizide, glimepiride

DPP-4 Inhibitors- 

Sitagliptin, Linagliptin

Different types of insulin for type-1 diabetes- 

Bolus insulin 

• Rapid-acting insulin
• Short-acting insulin

Basal Insulin 

• Intermediate-acting insulin
• Long acting /ultra long acting insulin

Premixed Insulin 

It is a combination of rapid acting insulin and intermediate insulin.

Can I cure my Type-2 diabetes? 

Type-2 diabetes is manageable.

Sugar levels can be controlled.

It cannot be cured permanently.

One can attain remission by managing constant sugar levels.

What is the working of type-2 diabetes drugs?

Type -2 drugs work in 3 ways-

• Reduce sugar production in the liver
• Stimulate insulin release
• Increase insulin sensitivity

Is diabetes manageable? 

The excessive sugar levels can be managed and lowered to the controlled limits.

It requires effective management strategy-

• Daily Monitoring and Care
• Diet and Lifestyle

What are the warning sugar levels?

• Prediabetes fasting – 100 – 125 mg /dl
• Diabetes fasting – 126 mg /dl
• Low blood glucose – 70 mg/dl

What is HbA1c?

It is the average blood sugar level measured over a period of 3 months.

The third-party manufacturer for Anti-Diabetic Combination- 

Aprazer Healthcare is the top pharmaceutical manufacturer.

Manufacturing global quality products, we are the drug suppliers worldwide.

We export a range of products to Asia, Africa, and America.

Our antidiabetic combination manufacturer products include-

• Linagliptin 2.5mg/5mg + Dapagliflozin 5/10mg
• Dapagliflozin 5/10mg

Why choose us?

• WHO-GMP /EU-GMP certified manufacturing facilities
• Robust quality controls
• Global distribution
• Cost-effective manufacturing

Aprazer Healthcare ranks as the leading drug manufacturer.

With a decade-long experience in manufacturing global standard hepatology and oncology drugs and flexible manufacturing capabilities, sets us apart as the leading oral solid dose contract manufacturer. 

What are oral solid dosage formulations?

Oral dose formulations are medicines to be ingested orally.

These are solid formulations such as –

Tablets, capsules, and powders.

They are swallowed or dissolved in the mouth.

These travel through the gut for absorption.

What are the different types of oral solid dosage formulations?

The oral solid dosage forms include the –

Tablets – These are the compressed drug formulations.

The API and the excipients are pressed to form smooth tablets.

The advanced dosage formulation comprises the modified release tablets.

Tablets based on release pattern –

• Immediate release tablets- 

These are compressed tablets that release the drug directly into the bloodstream.

• Sustained release tablets – The drug is released slowly with time.
• Controlled release tablets– The drug is released at the predetermined rate.
• Extended release tablets– Prolonged drug release over an extended period of time.

The tablets are also coated differently to target release or to mask the taste.

Capsules – The powdered drug is dispensed into capsule shells.

The different types of capsule shells are the hard gelatin capsule and soft gelatin capsules.

The hard gelatin capsules encapsulate powdered drugs and pellets.

The soft gel capsules are used to dispense liquid formulations.

Based on release profile, these are classified as –

Immediate release capsules – These lead to release of the medication to the stomach.

Extended release capsules – These lead to drug release over an extended period.

What are the benefits of oral solid dosage formulations?

• Patient compliance/safety
• Longer shelf life
• Uniformity in content
• Flexible release
• Low cost
• High stability
• portability
• logistic simplicity

Why choose Aprazer Healthcare for OSD drug manufacturing?

Aprazer Healthcare is a globally chosen pharmaceutical manufacturer.

Having a track record of compliance with zero history of audit failure, we are highly trusted and accepted.

Regulatory compliance – 

We strictly adhere to the international regulatory standards.

Our manufacturing facilities are WHO-GMP /EU-GMP compliant.

Advanced manufacturing capabilities – 

Leveraging advanced technology, we are capable of manufacturing advanced drug formulations.

• Small-scale sample batches
• High volume productions
• Dedicated blocks for high potency drugs or hormones.

Reliable supply chain – 

• Authentic raw material sourcing
• Dedicated production lines
• Closed system transfers
• Cold chain supply

Transparent cost and Long –term viability 

• We ensure transparent values and costs.
• No hidden charges.
• Affordable cost
• Uncompromised quality.

FAQs 

Which is the leading third-party tablet manufacturer from India?

Aprazer Healthcare manufactures a comprehensive range of tablets.

All types of modified-release tablets.

Which is the leading third-party capsule manufacturer from India? 

Aprazer Healthcare leads in manufacturing advanced capsule dose formulations.

Gastro-retentive capsules

Modified release capsules

Rheumatology
Rheumatic diseases- 

These are autoimmune disorders.

The immune system starts to attack the body.

It causes incredible pain and inflammation in joints.

• Autoimmune arthritis
• Musculoskeletal inflammation
• Systemic Lupus Erythematosus
• Sjögren’s Syndrome
• Chronic gout
• Ankylosing Spondylitis
• Fibromyalgia

The common rheumatology disorder- 

Rheumatoid arthritis – affects millions of people worldwide.

It is a progressive joint destruction and systemic inflammation.

It leads to significant physical disability.

It significantly affects women.

What can be rheumatoid arthritis symptoms? 

• Chronic fatigue
• Chronic pain
• Joint pain
• Stiffness
• Swelling
• Joint inflammation

Does rheumatoid arthritis only affect the joints?

It is not confined to joints.

It leads to systemic inflammation.

It affects the entire body.

• Eyes /mouth – Dry mouth, irritation in the eyes.
• Lungs – Tissue scarring and shortness of breath.
• Skin – lumps under the skin
• Blood – Anemia /chronic fatigue

The role of corticosteroids in rheumatoid arthritis-

These drugs widely bridge the treatment.

These are widely used to manage inflammation.

They reduce sudden flare-ups.

These slow down the joint damage and reduce tenderness.

What are rheumatology medicines?

Rheumatology drugs are specialty care medicines.

These drugs are used to treat joint and immune system disorders.

The rheumatology drug regimen includes –

• Traditional DMARDS
• Biological treatments
• Anti-inflammatory drugs

DMARDs – These are disease-modifying drugs.

These are widely used to treat inflammatory and autoimmune conditions.

These calm down the overactive immune system.

It stops the physical damage to the joints.

The drugs include –

• Methotrexate- Trexazer 50 mg
• Hydroxychloroquine- Hqkast 200
• Sulfasalazine and Leflunomide

Biological inhibitors –

These are complex drugs grown from living cell sources.

They block specific proteins.

It reduces the immune activity, reducing inflammation.

Tofamark – Tofacitinib 5mg

Symptomatic relief medicines- 

• Pain killers – These are the NSAIDs and pain-relieving drugs.

They are widely used to bring symptomatic relief to pain or inflammation in the joints and cartilage.

• Corticosteroids- 

These are powerful immunosuppressants.

They are anti-inflammatory. These are steroidal in nature and bring quick short-term relief.

Which are the widely used rheumatology medicines?

• Hqkast 200- Hydroxychloroquine Sulphate 
• Tofamark – Tofacitinib Tablets 5 mg

Which is the leading rheumatology drug manufacturer?

Aprazer Healthcare is a pharmaceutical manufacturer.

We specialize in manufacturing rheumatology drugs.

Adhering to WHO-GMP and EU-GMP, we manufacture global standard pharmaceutical products.

We are the leading rheumatology drug exporter.

Our extensive product range includes-

• DMARD drugs
• Immunosuppressive agents

Tacrolimus (Xgraf) is a strong immunosuppressant.

It is prescribed worldwide, preventing acute graft rejection.

Improving long-term outcomes, it is the mainstay immunosuppressive treatment drug used in post-kidney transplantation management.

• Reduces the risk of acute rejection by 30- 40 percent.
• Lowers the risk of graft loss by 44 percent (six months of use).

Xgraf (tacrolimus), manufactured by Aprazer Healthcare, is a highly affordable, globally available tacrolimus brand.

Tacrolimus tablets manufactured by Aprazer Healthcare are available in 3 strengths-

• X-Graf 0.5 – Tacrolimus 0.5 mg 
• X-Graf 1 – Tacrolimus 1mg 
• X-Graf 2 – Tacrolimus 2 mg 

As a leading nephrology medicine manufacturer, Aprazer Healthcare manufactures a diverse range of immunosuppressants widely used in kidney transplantation.

Manufacturing precision-dose drugs with uncompromised quality, Aprazer Healthcare is a globally trusted brand for immunosuppressants.

We are the top drug exporter for immunosuppressive agents worldwide.

What is the working of Tacrolimus (Xgraf)?

It suppresses the activation of T-cells.

It calms down the immune system.

It prevents immune activity against the foreign organ.

It has targeted action suppressing white blood cells.

Why is Tacrolimus (Xgraf) a first-line drug for transplant prevention?

Tacrolimus is a gold standard drug –

• More potent than old cyclosporine.
• Prevents acute rejection episodes.
• Offers long-term graft protection.
• Fewer cosmetic side effects

Other uses of Tacrolimus(X-Graf) – 

It is widely used to treat severe autoimmune conditions.

• Rheumatoid arthritis
• Nephrotic syndromes
• Severe skin allergies
• Eczema

Why is regular blood monitoring required with Tacrolimus (X-Graf)? 

Besides its wide utility, Tacrolimus has a narrow therapeutic window.

It has low safety margins.

A slight increase in dose can be life –threatening.

It may induce toxicity or lead to graft rejection.

Blood levels of the drug are measured 12 hours after the dose and immediately before the next dose.

Fluctuating drug levels can lead to –

• under- immunosuppressive effect
• over- immunosuppressive effects

What are the notable side effects of Tacrolimus (X-Graf)? 

Tacrolimus significantly constricts the blood vessels

It reduces blood circulation/flow.

Renal toxicity – The use of tacrolimus can cause acute kidney injury.

The long –term use leads to reduced blood supply to the nephrons.

It leads to chronic kidney injury.

Post-transplant diabetes- 

It damages the pancreatic cells, elevating sugar levels.

High blood pressure – It causes narrowing of the blood vessels and also activates the sympathetic nervous system, raising the blood pressure.

Risk of severe infections- Targeting the white blood cells, lowers the body’s immunity.

It lowers resistance against infections.

Neurotoxicity- The drug reaches the brain.

It irritates the peripheral nerves.

Leads to shaky movements/tingling sensations.

Why choose Aprazer Healthcare for immunosuppressive agents?

Aprazer Healthcare is the leading generic drug manufacturer.

• WHO-GMP-certified manufacturing
• Precision dose formulations
• Stringent quality controls
• Robust distribution network

Indian pharmaceutical exports serve as a lifeline, enabling access to essential healthcare.

The Quick facts-

• India ranks as the 3rd largest pharmaceutical drug manufacturer.
• Accounts for 20 % of global generic exports.
• India supplies 70 % of the world’s antiretrovirals.
• India forms the backbone of GLOBAL immunization, supplying 60 % of the total vaccines to UNICEF /WHO.

At Aprazer Healthcare (leading pharmaceutical manufacturer in India), we manufacture a global range of lifesaving medicines.

As a leading drug exporter from India, we are trusted for world–class quality and stringent regulatory compliance.

Implementing cutting–edge technology, we specialize in manufacturing complex formulations.

Our export portfolio includes –

• Anticancer drugs
• Hepatitis B medicines
• Hepatitis C medicines
• HIV medicines

Key markets for Pharma exports –

• North America – 

It is a global hub for pharmaceutical trade.

Driven by heavy domestic demand, it relies heavily on foreign generic imports.

Pharmaceutical exports to North American countries exceed $123 billion.

India accounts for roughly 13 to $ 15 billion in drug exports.

It is the top supplier of affordable generic drugs.

The key imports include –

• finished dosage formulations
• complex generics
• biosimilars
• Europe union and UK

These are highly regulated markets.

They demand exceptional quality assurance.

Key imports include API and generic drugs.

India supplies 33% of total generic prescriptions in the UK.

Europe’s pharma market is expected to reach €400 billion by 2027.

Germany, the UK, and the Netherlands are the leading entry ports for continental distribution.

• Latin America (Brazil, Mexico) 

It is a rapidly expanding market.

Brazil and Mexico are the leading importers of bioequivalent generics.

South and Central America heavily rely on generic imports for –

API, Bulk drugs, diabetes, and cardiovascular drugs.

• Africa (South Africa, Kenya, Nigeria)

The African market is projected to grow between $34 billion and $70+ billion over the next decade.

Africa is a high-volume pharmaceutical market.

It deeply relies on imported products.

The key medicines of export include –

Antimalarials, antibiotics, vaccines, and anti-retrovirals.

It is the target of healthcare programs by UNICEF and WHO.

• The Middle East – 

These are the Gulf nations that demand premium formulations.

The global drug export in the Middle East is expected to reach $50 billion by 2026.

The key import products include –

OTC drugs, branded generics, and specialty care medicines.

Due to simplified regulatory pathways, it is the destination for branded product lines.

• South East Asia – 

These countries rely on Indian pharmaceutical imports.

India serves as the best cost-effective drug source in comparison to Western markets.

Vietnam, the Philippines, Myanmar, and Indonesia are the top destinations for export.

ASEAN regulatory framework accepts WHO-GMP baseline compliance.

• CIS and Russia –

Russia accounts for major Pharma imports from India, scaling to $55.7 million in immunological treatments.

The unified single dossier framework eases Indian drug approvals.

The international ICH-compliant trials done in India are now recognized and accepted by the CIS countries.

It streamlines access to other markets –

Belarus, Kazakhstan, Kyrgyzstan, and Armenia.

The key Medicines Exported from India 

Oncology drugs –

India supplies 60 percent of global generic anticancer drugs.

India supplies anti-cancer drugs to 120 + countries.

The key exports include –

Tyrosine kinase inhibitors and chemotherapy injections.

Antiinfectives (Antibiotics and antimalarials)- 

This is the largest volume segment.

The key drugs include-

cephalosporins, penicillins, and macrolides.

18-20 percent of global antibiotic volume is exported by India

Neurological medicine /pain killers –

The massive worldwide demand for OTC painkillers drives high export volumes.

The key drugs of export include the NSAIDs, antidepressants, and the anticonvulsants.

Cardiovascular drugs – 

Indian exports cover 12 -14 % of the global cardiovascular drug market.

The drug exports include – statins, ACE-inhibitors, beta-blockers , calcium channel blocker.

Antivirals and antiretrovirals – India is the leading exporter of HIV drugs in high disease burden areas.

Antidiabetic drugs – The chronic illness projecting a global crisis.

The export volume is dominated by metformin and oral hypoglycemic.

GIT medicines – 

India manufactures and exports a wide variety of GIT medicines.

The key exports include – proton pump inhibitors, H2 blockers and antacids.

Why is Aprazer Healthcare a trusted drug exporter?

• Regulatory compliance
• Assured quality
• Robust Supply chain
• Global distribution
• Wide product portfolio
• Transparent communication

Our oral solid manufacturing plant, established at Haridwar (700, OOO sq. feet), equipped with modern technology, is capable of manufacturing versatile solid dosage formulations.

We manufacture all types of tablets/capsules.

• Modified release tablets /capsules
• Enteric coated tablets
• Film-coated tablets
• Sugar-coated tablets
• Liquid-filled hard capsules
• Acid-resistant capsules
• Soft/hard gelatin capsules
• HPMC capsules

What is meant by CMO in the pharmaceutical industry? 

CMOs are drug manufacturing companies. These manufacture the drug based on formulas provided by the contract party.

These manufacture drugs on behalf of other organizations under a defined contractual agreement.

The core process of CMOs working involves –

• Product specifications / material procurement
• Regulatory compliance
• Quality management
• IP protection
• Supply chain continuity risks
• Optimizing cost and capacity

Why are CMOs beneficial for the leading brands?

CMO’s focus on scaling up production.

• Prevents drug shortages.
• Aligns with the drug demand
• Eliminates the cost of infrastructure
• Safeguards brand integrity through scalable productions
• Reduces supply chain responsibility
• Enhances market growth
• Faster product entry to the market.

Why is Aprazer Healthcare the right CMO for your pharmaceutical products?

Proven Expertise and Experience – 

Our expert leaders from the core technical background exhibit leadership in manufacturing advanced generic drugs.

Having more than a decade of experience in manufacturing world–class generics, our leaders share a unique blend of expertise in understanding formulations /chemistries.

Operational Excellence – 

Enduring technical advancements, we specialize in manufacturing complex products, sterile and difficult oral dosage formulations.

• Low –dose uniformity
• Taste masking
• Modified-release drugs

Risk assessment to prevent wastage or ruining of batches.

• Running pilot batches before commercial supply.
• Automated workflow

Quality and compliance – 

We have a track record of spotless audit history.

• Strict adherence to Good Manufacturing Practices.
• WHO-GMP certified /EU-GMP certified manufacturing units.
• In- house testing
• Complete batch manufacturing record.

Robust distribution network 

We have an advanced distribution network ensuring product integrity/safety.

• Cold chain supply logistics
• Real-time tracking
• Automated inventory systems
• complete regulatory compliance

Transparent Communication – 

Our core values stand on building long-term trust.

• Transparent dealings
• sharing true data
• Protecting proprietary client formulas and data.

Understanding the urgency and demand for the products, we are flexible in our working times and also ready to implement new technology to deliver consignments on time.

With our collaborative approach to solving hurdles in the supply chain or manufacturing, we are a trusted pharmaceutical CMO worldwide.