What are the common approaches to cancer treatment? 

Cancer treatment involves a comprehensive approach.

It includes tumor removal, shrinking tumor growth, preventing tumor spread, and preventing future recurrence.

• Surgery – It is an invasive method that physically removes cancer cells /tumors.
• Chemotherapy – It is the systemic circulation of toxic drugs into the blood.

The agents kill the cancer cells circulating in the body.

• Radiation therapy- It is the use of high-energy particles on the tumor.

It kills the cancer cells and shrinks the tumor.

The types of medicines for cancer treatment- 

• Chemotherapy drugs-

These are the toxic agents, targeting the rapidly dividing cancer cells.

The chemo drugs are given orally as well as intravenously.

The commonly used chemotherapy drugs-

• Carboplatin Injection – Carbokast 150mg
• Doxorubicin injection – Dorucin-10mg
• Paclitaxel injection – Paclikast 260mg
• Capecitabine tablets – Capekast

• Hormone therapy drugs – 

These are the hormonal analogues.

They are effective against hormone–sensitive tumors.

These block the synthesis of hormones or block the receptors for hormonal function.

These are widely used in breast cancer/prostate cancer treatments.

The commonly used hormone therapy drugs for breast cancer –

• Letrozole – Letrakast
• Anastrozole – Anzakast

Drugs for prostate cancer-

• Enzalutamide –Indenza
• Bicalutamide- Bicazer 50mg
• Abiraterone- Abirakast 500 mg

1. Targeted therapy drugs – 

These are drug formulations having targeted action.

They directly act on the cancer cells.

These have fewer side effects.

These do not harm healthy cells.

The common medicines include-

• Olaparib-Olabir 150mg
• Palbociclib- Palbocib-125 mg

• Immunotherapy – 

These work by enhancing the body’s immune system.

They increase the immune activity to destroy the cancer cells.

Examples include –

• Monoclonal antibodies
• Immune checkpoint inhibitor
• Cytokine inhibitors

Which are the 5 deadliest cancers?

1. Lung cancer 

It is the most prevalent cancer leading to cancer deaths globally.

It is often diagnosed at advanced stages.

2.5 million Cases are diagnosed every year.

2. Colorectal cancer –

It is the next leading cause of cancer deaths.

The benign polyps turn into cancer after 10 -15 years.

3. Liver Cancer- 

It is an aggressive form of cancer.

It is directly linked to Hepatitis B and C viral infections /alcohol use.

4. Stomach cancer – 

Stomach cancer accounts for 700,000 to 800,000 deaths annually.

It accounts for 5 % of all new cancer diagnoses.

5. Breast cancer –

It is the most common female cancer.

It accounts for 25% of cancers in women.

1 in 8 women is at risk of developing cancer in her lifetime.

What are the side effects of cancer drugs?

Chemotherapy side effects – 

• Weakness
• Nausea
• Vomiting
• Hair loss
• Mouth ulcers
• Neuropathy
• Cognitive side effects

Targeted therapy side effects – 

• Severe skin reaction
• Diarrhea
• Elevated liver enzymes

Hormone therapy side effects – 

• Hot flashes
• Night sweats
• Bone thinning

Which is the oncology medicine manufacturer in India?

Manufacturing world-standard drugs, Aprazer Healthcare is a global oncology brand.

We are the largest generic drug manufacturer and a certified pharmaceutical exporter from India.

We supply an extensive range of oncology orals and oncology injectables to leading countries.

Meeting the global oncology medicine demand, we are trusted across governments worldwide.

Critical care drug manufacturing involves strict quality controls facing stricter regulatory oversight compared to oral drug manufacturers.

Aprazer Healthcare understands the critical requirement to maintain adequate sterility and quality manufacturing of optimum-quality critical care injectables, saving lives.

With our advanced manufacturing infrastructure, we are the top critical care medicine manufacturer and exporter from India.

Having a long track record of manufacturing global-quality critical care products, Aprazer Healthcare has built a strong reputation in global pharmaceutical markets.

What are critical care medicines and the need for stringent quality controls?

Critical care medicines are the life-saving drugs used in critical life threatening illness.

These are typically used in hospitals’ ICUs (intensive care units).

These are widely used to treat-

• Respiratory failures
• Severe infection
• Severe trauma
• Acute organ failures
• Cardiovascular crises

Due to narrow therapeutic index and rapid action, it requires stringent quality control.

The patient in critical condition has zero margins to tolerate discrepancies, which may lead to fatal consequences.

The important certifications required for critical care medicines manufacturers and exporters from India-

WHO-GMP certification – 

It is the international certificate that ensures the global compliance of drugs.

It ensures standardized practices for injectables manufacturing.

• Quality controls
• Equipment calibration
• Sterile manufacturing
• Documentation process
• Raw material quality

ISO certification – 

It is the international standardization method that ensures WHO – GMP compliance.

It is an additional assurance that covers sterile injectable production.

Domestic licenses – 

Drug manufacturing license –

It is the license issued by the state drug authorities.

It ensures the manufacturing facilities for sterile product manufacturing.

Schedule M compliance – 

These are the rules stated under the Drugs and Cosmetics Act, India.

It includes good manufacturing practices and lays specific requirements for sterile product manufacturing.

Aprazer Healthcare’s facility and infrastructure standards for manufacturing premium quality critical care medicines- 

• Clean room environmental controls – 

• HVAC airflow systems (HEPA filters).
• Separate zones for Grade A to Grade D injectable manufacturing.

Airlock systems and aseptic processing barriers

• Advanced utilities –

• Validated water systems
• Orbital-welded 316L stainless- steel pipelines for zero deadlocks.
• Clean steam generators
• Automated gas decontamination systems
• Particulate and pyrogen control systems
• Quality Control Capabilities-

In-house testing laboratories

Trained staff and advanced instruments for critical tests for injectable.

• Documentation and Traceability 

Complete batch manufacturing records

Certificate of analyses

Partner with Excellence – 

Maintaining uncompromised quality standards, Aprazer Healthcare is a first choice for global pharmaceutical partnerships.

We specialize in manufacturing beta–lactam antibiotics, widely used in hospitals’s ICU (intensive care units).

Our flagship products include –

• Piperaxis- Piperacillin /Tazobactam injection
• Aptriax – Ceftriaxone injection
• Meroaxis – Meropenem

Aprazer Healthcare is the leading pharmaceutical exporter based in Delhi.

We operate through our WHO-GMP-compliant manufacturing facilities spread across Northern India.

Specialized in manufacturing global standard drugs, we lead in generic drug supplies to 80+ countries.

What are the certificates required for pharmaceutical drug export from India?

• Import /export code – It is an identification number offered to the company.

It is issued by the Indian Ministry of Commerce and Industry.

It is required for import /export of goods from India.

• Drug manufacturing /wholesale license- 

It is the document that ensures facility compliance and technical requirements.

The wholesale license allows for storage and distribution.

Mandatory regulatory certificates

• Certificate of Pharmaceutical Products – It is issued by the CDSCO.

It ensures that the drugs are approved for domestic sales.

Drugs are manufactured in compliance with global standards.

• WHO-GMP certification- It is usually required by the importing companies.

It ensures global standard product quality.

• Free sale certificate- It specifies the drug is safe to use and eligible for sales.
• Certificate of analysis – The laboratory issues a certificate that the drug batch meets precise chemical and purity standards.

Mandatory Technical dossiers

• Drug master file –It includes complete specifications about API, manufacturing process, quality control, and finished product details.
• Stability data report – It specifies the shelf life, expiry date sand the storage conditions.

What is an ISO certification?

It is a globally recognized seal on pharmaceutical products.

It ensures the product meets the global standards.

It is an export-ready product for global supplies.

Why is Aprazer Healthcare a chosen pharmaceutical exporter from India? 

Aprazer Healthcare, with WHO-GMP-compliant manufacturing, is a global drug supplier.

With global footprints across Asia, Africa, and America – we supply medicines to global hospitals, clinics, and national governments.

End-to-End regulatory support 

Aprazer Healthcare offers complete documentation support and regulatory expertise.

Our regulatory team stays updated with the changing regulatory frameworks.

We offer support from drug approvals to logistic, shipment reports.

• Digital documentation
• Shipping and logistics reports
• Custom clearance reports
• Country-specific drug approvals

Good Distribution Practices- 

• Temperature-controlled shipments
• Product traceability
• Product documentation
• Authorized logistic partners
• Tamper-evident packaging
• Disposal of expiry /returned products.

At Aprazer Healthcare, we ensure regular supply and uniform product quality across all consignments. 

The treatment regimen includes –

• Evaluation of viral count
• Testing for co-infections
• Evaluation of liver damage

It is then followed by an antiviral regimen and supportive therapies.

The direct-acting antivirals are well tolerated.

These cure 98% of infections.

What is the newest Hepatitis C treatment?

The Direct-Acting Antivirals –

These are the antiviral drugs that target the proteins /enzyme in the virus.

These inhibit the virus life cycle.

The varied class of antivirals is combined to provide an effective cure.

The drug combinations lead to 95 % virus elimination. 

• Prevents drug resistance- 

Hepatitis C is attacked at different sites.

It reduces the probability of viral mutation.

• Provides absolute blockage-

It blocks the cell cycle at multiple points.

• Higher efficacy- 

The combination therapy offers lower side effects and high cure rates.

The commonly used Hepatitis C combinations include – 

• Velakast- Sofosbuvir /Velpatasvir 400mg/100 mg
• Sofokast Plus- Daclatasvir and Sofosbuvir 60/400mg
• Sofokast- Sofosbuvir Tablets 400 mg
• Dacikast- Daclatasvir Tablets 60 mg
• Ribasure- Ribavirin Capsules 200mg
• Ledikast- Ledipasvir & Sofosbuvir Tablets

Is Hepatitis C curable?

Hepatitis C is cured by the daily oral regimen of DAAs.

These drugs inhibit the multiplication /replication of HCV.

The direct-acting antiviral combinations offer successful cure rates.

Does curing Hepatitis C once make you immune for the rest of your life?

The antivirals completely cure Hepatitis C.

It does not provide future protection.

The hepatitis C virus undergoes innumerable mutations.

The body does not produce protective antibodies against all genotypes.

The long-term hepatitis also leads to immune scarring.

The original virus may not return, but the body may interact with a new strain.

Which is the pan-genotypic Hepatitis C combination used globally?

Velakast (Sofosbuvir/Velpatasvir) manufactured by Aprazer Healthcare.

It is a fixed-dose combination containing –

• Sofosbuvir – 400 mg
• Velpatasvir – 100mg

It is a highly prescribed antiviral combination used in Hepatitis C treatment.

Beyond a comprehensive treatment, Velakast offers an affordable treatment regimen.

Benefits of Velakast (Sofosbuvir/Velpatasvir) 

• It is effective against all 6 strains of Hepatitis C.
• It can be used in children aged 3 years or older.
• It is safe to be used in advanced liver disorders.
• Easy dosing – Once daily pill for 12 weeks

Which is the top Hepatitis C medicine manufacturer and global exporter? 

Aprazer Healthcare (hepatology medicine manufacturer) is a top hepatitis C medicine manufacturer.

We are the largest drug exporter from India, manufacturing global-quality antivirals.

As a leading Pharma third-party manufacturer in India- Aprazer Healthcare manufactures a diverse range of generic and branded drugs.

Aprazer Healthcare is a trusted brand in the global markets.

Aprazer Healthcare is a leading pharmaceutical manufacturer from India.

Reaching a decade of pharmaceutical excellence, we are continuously expanding our portfolio to make healthcare affordable and accessible.

Manufacturing global-standard products, we are a leading pharmaceutical exporter from India.

What is the need for WHO-GMP certification?

Pharmaceutical manufacturers require WHO-GMP certification to ensure drug quality and safety.

It ensures the manufactured drugs are of global quality.

It is a standard protocol that determines whether the medicine is safe and effective to be used by humans.

It is mandatory for global pharmaceutical export.

Our commitment to manufacturing excellence – 

We are a certified manufacturer licensed with global health authorities like WHO- GMP, EU-GMP.

Based in Delhi, our manufacturing facilities are spread across Northern India.

Holding expertise in manufacturing all forms of solid oral dosage formulations, we are the leading drug exporters from India.

Advanced Infrastructure – 

Having world-class infrastructure, we are capable of manufacturing modified dosage forms.

Equipped with the latest advanced technology-

• Aseptic manufacturing and filling
• Continuous manufacturing
• Real-time monitors
• Alert Sensors
• Smart packaging and serialization

Our stringent quality control parameters 

• Robust quality measures- 

We manufacture high-quality products incorporating –

• GMP measures
•  Risk assessment

• Personnel Hygiene- 

• Trained staff
•  Cleanliness framework
• Hygiene practices
• Protective clothing
• Decontamination

• Qualification and validation – 

Maintaining proper standardization of –

• All equipment
• manufacturing systems
• Other utilities like water and air supply.

• Quality control operations- 

Our quality control parameters involve sampling protocols –

• Environment monitoring
• Review of batch records
• Stability testing

• Documentation and records 

Each process of manufacturing or action is recorded.

It includes-

• Master formulae
• Batch processing records
• Log books for equipment usage and calibration, etc.

• Internal quality audits 

Internal inspections help us mitigate errors.

Our process includes –

• Verification of SOPs.
• Identify areas for correction.
• Adopt successful preventive measures.

World–class medicines with uncompromised quality- 

Aprazer Healthcare is accredited by WHO-GMP.

From sourcing the raw material to the final product formulation, every process is verified and documented.

Our core values comprises transparency and adherence to regulatory norms.

Our product portfolio comprises a diverse range of life-saving drugs-

• Anticancer medicines
• Hepatitis B medicines
• Hepatitis C medicines
• HIV medicines

Aprazer Healthcare is a trusted global healthcare partner. 

India supplies about 60 percent of the global oncology market.

Known as the pharmacy of the world, India is the top generic medicines manufacturer.

It is the largest oncology drug exporter.

Supplying affordable anticancer drugs globally, Indian pharmaceuticals are a crucial lifeline for countries worldwide.

Are generic oncology drugs safe?

The generic anticancer medicines are brand-equivalent medicines.

These are as safe as their branded counterparts.

• Similar in efficacy and safety profile
• Have the same API
• Undergo the same manufacturing processes and quality controls

How have generic anticancer drugs revolutionized cancer treatment and care?

Generic drugs have broken the monopolies, significantly lowering the treatment costs.

It has shifted the paradigm from financially ruinous cancer treatment to affordable regimens.

The patented branded drugs have been highly expensive and remained out of reach for the masses.

• Generic drugs are 80-90 percent lower in cost.
• Low prices help better adherence to long-term treatment.
• The multiple generic drug supplies minimize global drug shortages.
• It reduces overwhelmed costs and expenditure on hospitals/national healthcare budgets.

Know the 5 top oncology medicine manufacturers- 

Cipla – Cipla is a global pharmaceutical company.

It manufactures an extensive range of pharmaceutical products.

Its product portfolio spans across all therapeutic segments.

It operates globally, supplying in 80+ countries.

Sun Pharma – It is the largest pharmaceutical supplier of generic drugs.

It has a global supply network and has 40+ manufacturing facilities worldwide.

It holds a major share in generic supplies in both domestic and international markets.

It manufactures pharmaceutical products in all therapeutic segments.

Aprazer Healthcare – Aprazer Healthcare is a key player in global oncology markets.

It is the leading supplier of anticancer drugs to Asian, American, and African countries.

It manufactures global quality products, accepted by the national government.

Manufacturing generic oncology injectable and orals, Aprazer Healthcare is a leading oncology medicine exporter from India.

Natco Pharma – It specializes in manufacturing complex generics.

It is the largest manufacturer of targeted cancer therapy drugs.

It supplies oncology products to 50 + countries.

Beyond oncology, its product portfolio includes – Cardiology, diabetology, and neuroscience.

Dr. Reddy Laboratories – 

It is India’s premium pharmaceutical company.

It specializes in manufacturing APIs/branded generics.

It is the leading biosimilars manufacturer.

It manufactures products across all therapeutic areas, including –

Gastroenterology, cardiology, dermatology, and oncology.

What makes Aprazer Healthcare a top oncology medicine manufacturer? 

Aprazer Healthcare is a leading pharmaceutical partner delivering the first-line chemotherapy drugs to global hospitals, national governments, and community supplies.

We manufacture a range of life-saving drugs.

Trusted worldwide, we supply products to 50 +countries.

WHO-GMP certified manufacturing capabilities – Aprazer Healthcare is a pharmaceutical manufacturer accredited by the global health authorities.

Our manufacturing units span 70,000 square feet. 

We specialize in manufacturing oncology orals and oncology injectables.

Modern Infrastructure – Leveraging modern techniques, we develop Novel drug formulations.

Manufacturing high-volume parenteral products, we are a recognized oncology injectable exporter.

Robust distribution network – 

With our strong distribution network and intact cold chain supply, we deliver world–class pharmaceutical products globally.

Aprazer Healthcare supplies globally accepted and trusted pharmaceuticals. 

The advanced Anti-retroviral drugs have dramatically led to the decline of HIV infection.

The mortality rate has fallen by about 70 percent.

The drugs reduce the viral count to undetectable levels, significantly reducing the risk of transmission.

The anti –retroviral drugs make the disease manageable and increase survival rates/years.

The commonly used Lopinavir /Ritonavir combination – Lopikast 

Lopinavir /Ritonavir (Lopikast) is widely used for HIV treatment.

It is a globally available HIV medicine.

It is a combination of strong antivirals with a booster molecule.

Ritonavir increases the efficacy of Lopinavir many fold.

The key benefits include- 

• It suppresses HIV virus to undetectable levels.
• It delays HIV progression to AIDs.
• It has a high barrier to resistance.

Aprazer Healthcare – Advancing HIV treatment 

Aprazer Healthcare specializes in manufacturing HIV drugs.

Manufacturing a large range of antiretroviral combination drugs, we are a top tier generic HIV medicine manufacturer.

With an aim to eradicate HIV, we manufacture affordable HIV generic combinations.

Aprazer Healthcare is at the forefront in saving lives in HIV epidemic areas.

Aprazer Healthcare is a reliable drug exporter, supplying affordable HIV medicine to countries in Africa, Asia and America.

Why is Lopinavir combined with Ritonavir? 

Lopinavir is a strong antiviral medicine.

Ritonavir is added to enhance the effect of Lopinavir.

Lopinavir breaks down at a faster rate in the body.

Ritonavir inhibits the breakdown.

It prolongs lopinavir activity.

Is it safe to be used in pediatric patients?

It is not recommended to be used in neonates before 14 days of age.

Children may require twice drug dosing than adults due to faster elimination of the drug.

Lopinavir /Ritonavir (Lopikast) is given in pregnancy. Is it safe? 

It is commonly used to prevent HIV transmission from mother to the child.

It reduces the risk of preterm delivery.

It does not harm the fetus.

Can Lopikast stop viral transmission? 

It drops the viral count to negligible.

It prevents transmission of virus from one person to another.

Lopinavir /Ritonavir (Lopikast) combination long-term side effects- 

• Hyperlipidemia
• Insulin resistance
• Fat accumulation around abdomen
• Fat wasting around arms, legs
• Increased risk of kidney stones
• Bone loss
• Pancreatitis risk

Lopikast (Lopinavir/Ritonavir) combination – The two drugs engineered to form a single pill offers high resistance barrier and uncompromised suppression.

Mycophenolate Mofetil is the core therapy drug to prevent acute organ rejection.

Mycophenolate Mofetil is available globally as Myfocept 500 and Myfocept 250.

It is a first-line drug in anti-rejection therapy.

What is Mycophenolate Mofetil (Myfocept 500)?

Mycophenolate Mofetil is an immunosuppressant drug.

It is widely used in organ transplant drug regimens.

It lowers immune activity and prevents the body’s rejection of the foreign organ.

Used in solid organ transplants –

• Liver transplant
• Kidney transplant
• Heart transplant

Aprazer Healthcare (pharmaceutical manufacturer) specializes in manufacturing specialty medicines.

We manufacture a global range of immunosuppressive agents and chronic disease medicines.

We are the leading specialty medicine exporter from India.

Manufacturing global standard drugs, Aprazer Healthcare’s products are accepted worldwide.

We supply immunosuppressive drugs to the leading hospitals and clinics.

How is Mycophenolate Mofetil (Myfocept 500) used in organ transplant therapy? 

It forms an important part of the organ rejection drug regimen.

It is combined with other drugs, forming a triple–drug regimen.

1. Mycophenolate Mofetil – It inhibits the formation of white blood cells.

These cells actively attack the new organ, causing immune rejection.

1. Calcineurin inhibitor– It halts the activation of the T cells (white blood cell type).

It down regulates the immune action of the T-cells.

1. Corticosteroid– It reduces the inflammation caused by transplant and suppresses immune flare.

Why is Mycophenolate Mofetil (Myfocept 500) combined with other drugs? 

When combined with other drugs

• It offers better immune suppression
• It can be used in smaller doses
• It prevents acute rejections
• It offers lower side effects
• It offers longer graft and patient survival

The standard adult dose of Mycophenolate Mofetil (Myfocept 500) 

Kidney transplant – For kidney transplant, the standard daily dose is 2g.

Liver /Heart transplant- For liver and heart transplant, the standard daily dose is 3g

Elderly patients – For elderly patients, the initial drug dose is low (500 mg).

Why is Mycophenolate Mofetil (Myfocept 500), the foundation for the anti-rejection regimen?

Targeted action – It specifically targets T and B lymphocytes.

It lowers harmful effects on other blood cells.

Lower steroid doses required- It is highly effective and requires low doses of corticosteroid, preventing steroid side effects.

Non-nephrotoxic – It does not harm the kidneys compared to other drugs.

It can be used long-term for organ preservation.

Hepatitis B is a global pandemic affecting 240 million people.

0.9 million new infection cases occur every year.

It is an infection (virus) directly affecting the liver.

Inconsistent treatment may lead to severe complications.

The virus damages the liver tissue.

The infection can lead to liver cirrhosis or liver failure.

It spreads easily through infected blood or body fluids.

Globally prescribed Hepatitis B medicine- 

Entecavir (Entekor) is widely prescribed for Hepatitis B due to its safer profile.

Entekor and Entekast are popular brands of Entecavir tablets.

It is highly affordable and globally accessible.

These are safe to use in children above 2 years of age and elderly patients.

Aprazer Healthcare manufactures it in two different strengths.

• Entekast -0.5  (Entecavir 0.5 mg)  tablets
• Entekast -1  (Entecavir 1 mg) tablets

Aprazer Healthcare is a hepatology medicine manufacturer and one of the top exporters of Entecavir (Entekor) tablets worldwide.

Manufacturing global-quality drugs, we export the largest range of Hepatitis B medicines.

Having an unparalleled distribution network and supply chain, Aprazer Healthcare is the global supplier of hepatitis medicines.

Our product portfolio comprises –

Hepatitis C and Hepatitis B medicines.

What is the working of Entecavir (Entekor)?

It does not eliminate Hepatitis B virus from the body.

It prevents the replication/multiplication of the virus.

It significantly lowers the viral load.

Why is Entecavir (Entekor) a preferred first-line treatment?

Doctors prefer Entecavir (Entekor) for treating Hepatitis B.

It has a safe profile.

• Highly potent
• Rapid action
• Lower risk of resistance
• It is safe to use in kidney impairment
• It is hepatoprotective
• It reverses liver damage
• Prevents disease progression

What is Entecavir (Entekor) dosage?

For untreated patients, it is used at 0.5 mg daily.

For patients who have developed resistance to lamivudine, the drug dose starts with 1 mg daily.

Children are given according to their body weight.

Does it prevent the spread?

Entecavir (Entekor) significantly reduces the viral count.

The virus levels fluctuate rapidly.

It does not prevent the spread.

Why is it important to get HIV tests before starting the treatment?

People co-infected with HIV must not use it alone.

It must be combined with other antiretroviral.

Its single use may lead to resistance against HIV.

You should not leave the medicine by yourself. Why?

Abrupt cessation of drug may lead to a hepatitis B flare-up.

It can rapidly lead to liver failure in conditions of liver scarring.

Why is Aprazer Healthcare a chosen brand for hepatology medicines?

Aprazer Healthcare specializes in manufacturing hepatology medicines.

We are a trusted brand for global hospital drug supplies.

Our strong attributes –

• WHO-GMP manufacturing facilities
• Quality assurance
• Global distribution
• Affordability
• Intact supply chain

Women account for 60 percent of osteoarthritis cases globally.

Postmenopausal women exhibit the highest disease burden.

Knee joints are affected first, followed by the hip joint and hands.

The earlier symptoms are mild and infrequent, so easily ignored.

Recognizing early signs and timely intervention prevents disease advancement.

Identifying the systemic or immune-based inflammation helps mitigate disease progression.

Irreversible damage can be prevented by early medications.

As the leading rheumatology drug manufacturer, Aprazer Healthcare manufactures a comprehensive range of rheumatology medicines.

We are the rheumatology drug exporters to international markets.

Following WHO standards and quality parameters, we manufacture drugs for global supplies.

Our flagship rheumatology medicines include-

• Hydroxychloroquine Sulphate-  Hqkast 200
• Tofacitinib- Tofamark

What are the reasons for developing arthritis in women?

Hormonal factors – 

Estrogen secretion stops after menopause.

Estrogen protects joints and controls inflammation.

A rapid fall in estrogen levels loosens the ligaments in the knee.

Physical structure- 

Women have wider hips compared to men.

The unequal pressure on the hips and knees increases the risk of hip damage.

Immune system differences 

Women are at risk of autoimmune diseases.

The immune system is more reactive compared to men.

Females are 2-3 times more affected by immune system attacks.

Obesity 

The increased weight leads to intense physical pressure on the knees/hip.

It causes systemic inflammation.

It damages the cartilage.

It also erodes the bones.

Pregnancy/childbirth 

Pregnancy causes changes in posture/ gait.

Childbirth causes a release of relaxin hormone.

It widens the pelvis.

It affects the cartilage and the joints.

It also causes metabolic changes, causing joint inflammation.

Emotional psychological factors

Chronic stress releases stress hormones.

These alter the immune response.

Sleep disturbances impair tissue repair.

Genetics – People with a family history of arthritis are prone to developing joint inflammation/arthritis.

The symptoms of arthritis- 

• Joint pain
• Swelling and stiffness
• Fluid accumulation in the joints
• Reduced motility

The early arthritis signs to be watched – 

• Stiffening of the joints while sitting /resting.
• Losing grip in the hands.
• Locking of the joints.
• Joints unable to bear full pressure
• Morning tenderness across the ankles and feet
• Persistent pain across the groin area
• Friction in moving joints

The arthritis treatment is focused on –

• Reducing joint pain
• Managing stiffness /swelling
• Preventing disease progression

The commonly used medicines include- 

Pain killers/ anti-inflammatory drugs.

• Analgesics help relieve mild –moderate pain.
• NSAIDs reduce inflammation and pain.

Disease-modifying anti-rheumatic drugs 

These are the drugs that prevent progressive damage of the joints.

These drugs target the immune pathways and inhibit the immune attack on the joints.

Corticosteroids 

These are the anti-inflammatory drugs.

They prevent sudden immune flare-ups.

It suppresses severe inflammation.

 Viscosupplementation- 

The hyaluronic acid injections are given in the joints.

It mimics the joint fluid properties.

It prevents joint damage.

How to prevent arthritis progression? 

• Active lifestyle
• Managing weight
• Proper diet.
• Quitting smoke
• Timely medication /treatment