How Does HIV Affect the Immune System?

HIV weakens the immune system.

It destroys CD4 immune cells used to fight infections.

HIV hijacks the immune system and uses it to make copies of itself.

The reduced activity of CD4 cells increases the risk of infections.

Stages of HIV infection:

HIV progresses through 3 stages-

  1. Acute HIV infection –

It is the early stage of the infection.

It usually occurs within 2–4 weeks.

The virus multiplies rapidly, invading the immune cells.

The viral load is very high during this period, increasing the risk of transmission.

A person may feel mild or no symptoms at all.

  1. Chronic HIV infection –

It is a condition in which the virus is active but does not reproduce rapidly.

It slowly damages the immune system if not treated.

A person may not feel any symptoms for years.

  1. AIDS –

It is the advanced stage.

The HIV infection has progressed to AIDS.

The immune system is badly damaged.

The CD4 count may fall below 200.

A person may develop specific opportunistic infections.

Can HIV-related damage be prevented or controlled?

HIV can be controlled when diagnosed and treated early.

Effective treatment can prevent disease progression and also control HIV-related damage.

Antiretroviral therapy –

Antiretroviral drugs form a vital part of HIV treatment.

These suppress the replication of HIV, reducing the viral count.

It helps the immune system bounce back and grow stronger.

The immune system starts to recover and helps fight opportunistic infections.

Opportunistic infection care –

A person must be regularly monitored for opportunistic infections.

Lifestyle management –

A healthy diet, proper health monitoring, and avoiding smoke and alcohol help support overall health.

Antiretrovirals used in HIV treatment –

These drugs target the life cycle of HIV at multiple stages.

HIV treatment usually focuses on combining drugs from different classes to target the HIV life cycle at multiple stages.

  • Tenofovir Disoproxil Fumarate, Efavirenz & Lamivudine tablets – Tudobest LE
  • Tenofovir Disoproxil Fumarate & Lamivudine tablets- Tudobest L
  • Tenofovir Disoproxil Fumarate, Emtricitabine & Efavirenz tablets – Virarazer

At Aprazer Healthcare, we manufacture advanced antiretroviral combinations.

Our manufacturing unit is equipped with modern technology to streamline manufacturing processes.

Our portfolio comprises generic antiviral drugs.

We are a generic drug manufacturer, recognized for manufacturing affordable medicines.

HIV Medicine Manufacturers and Exporters Companies in India

India is recognized as one of the major generic drug producers.

As a known generic antiretroviral exporter, Indian pharmaceutical companies manufacture a wide range of generic HIV medicines.

Indian government offers valuable support to pharmaceutical manufacturing through streamlined and fast regulatory approvals.

The top Indian companies manufacturing antiretroviral drugs –

Sun Pharma –

It is one of the leading players in pharmaceutical manufacturing.

It is a trusted manufacturing firm offering lifesaving drugs.

It has an extensive antiviral and antiretroviral portfolio.

Cipla –

It is a multinational company with its headquarters in Mumbai, India.

It is well known for its generic drug manufacturing.

Its portfolio spans API, OTC medicines, and specialty medicines.

Its core specialty areas include respiratory care and anti-retroviral.

Aprazer Healthcare –

Aprazer is a generic drug manufacturer based in India.

Its headquarters are located in Delhi.

Aprazer holds a significant position in supplying medicines in both Indian and international markets.

It specializes in manufacturing a wide range of drugs in multiple therapeutic segments.

Dr. Reddy’s Laboratories-

It is a global pharmaceutical company based in Hyderabad.

It manufactures a large range of generic drugs, APIs, biosimilars, and OTC drugs.

Its core therapeutic areas include oncology, gastroenterology, cardiovascular, and diabetology.

Lupin Limited –

It is a Mumbai-based multinational company.

It is globally known for manufacturing respiratory, cardiovascular, and anti-diabetic drugs.

Lupin specializes in manufacturing complex generics and continues to expand its anti-retroviral portfolio.

Why choose Aprazer Healthcare for HIV care?

Aprazer Healthcare is a specialty medicine manufacturer.

At our regulatory-compliant manufacturing unit, located in Haridwar, we manufacture drugs meeting the applicable quality standards.

We have robust quality assurance and quality control systems.

We are equipped with an advanced supply chain offering reliable temperature-controlled transport.

Our core manufacturing portfolio includes antivirals and antiretrovirals.

  • Hepatitis B medicines
  • Hepatitis C medicines
  • HIV medicines

Committed to HIV care, the portfolio extends across a comprehensive range of antiretrovirals.

  • Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
  • Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
  • Protease Inhibitors (PIs)
  • Integrase Strand Transfer Inhibitors (INSTIs)
  • Fixed-Dose Combinations (FDCs)

Our flagship HIV Fixed-Dose Combinations (FDCs) include –

Virarazer – Tenofovir, Emtricitabine, Efavirenz

Tudobest-LE – Tenofovir, Efavirenz, Lamivudine

Aprazer Healthcare – A Reliable Partner in Contract Drug Manufacturing

We offer trusted services as a Contract Drug Manufacturing Organization (CDMO).

With world-class infrastructure, we have dedicated units for manufacturing specialty drugs.

  • AHU systems
  • Advanced utility systems
  • Stringent cross – contamination and environmental controls
  • Safety and regulatory compliance
  • Cold chain and storage infrastructure

Our business ethics include-

  • Transparent dealings
  • Flexible minimum order quantities (MOQ)
  • Consistent quality

Rheumatology Medicine Manufacturer Companies in India

Rheumatology is a branch of medical science that diagnoses and treats musculoskeletal disorders, inflammatory conditions, and autoimmune diseases.

Common rheumatology disorders include –

  1. Osteoarthritis – It is a disorder of the joints, caused by damage to the cartilage in the joints.

It affects the knees, hips, and spine.

  1. Gout – It is an arthritis caused by uric acid crystal deposits in the joints.

The crystals lead to sharp pain and inflammation in the joints.

  1. Rheumatoid Arthritis – It is an autoimmune condition in which the joint lining gets damaged.

It results in joint damage, causing pain and inflammation.

  1. Fibromyalgia – It is characterized by pain, sleep disturbance, and fatigue.

The commonly used medicines in rheumatology disorders –

The treatment in rheumatology aims to control further damage, swelling, and pain.

  • Disease-Modifying Antirheumatic Drugs (DMARDs)
  • Corticosteroids
  • NSAIDs

The top 5 manufacturers of Rheumatology drugs in India

Intas Pharmaceuticals – It is a multinational company headquartered in Ahmedabad, Gujarat.

Intas is known globally for manufacturing biosimilar drugs.

It is a market leader in manufacturing high-barrier autoimmune and musculoskeletal therapies.

IPCA Laboratories – It specializes in manufacturing conventional drugs for rheumatology disorders.

Its core therapeutic areas include DMARDS and NSAIDs

Aprazer Healthcare –

It is a Delhi-based pharmaceutical company with expertise in rheumatology.

Aprazer is a rheumatology drug manufacturer and exporter.

Its portfolio comprises commonly used NSAIDs and DMARDs.

Torrent Pharmaceuticals – it is an Indian pharmaceutical company headquartered in Ahmedabad, Gujarat.

Its rheumatology segment comprises biologics, biosimilars, and DMARDs

Alkem Laboratories – It is a premier Indian pharmaceutical manufacturer, headquartered in Mumbai.

It specializes in manufacturing bone health and rheumatology drugs.

Flagship rheumatology medicines by Aprazer Healthcare –

Tofamark (Tofacitinib 5mg) – As a targeted DMARD, it is used to treat inflammatory conditions (psoriatic arthritis, rheumatoid arthritis).

HQKAST-200 (Hydroxychloroquine Sulfate 200mg) – It is a traditional DMARD drug, used to treat SLE and rheumatoid arthritis.

Trexazer- 50 (Methotrexate) – It is an immunosuppressive agent and a DMARD.

It is used to control inflammation caused by an autoimmune condition.

Why choose Aprazer Healthcare for rheumatology medicines?

  • Regulatory-compliant manufacturer
  • Stringent quality controls
  • Advanced infrastructure
  • International supply
  • Comprehensive portfolio

Aprazer Healthcare also offers CDMO services –

  • End–to–end regulatory support
  • Trusted services
  • Flexible Minimum Order Quantity (MOQ)

Top 5 Gastroenterology Medicine Manufacturers in India

The rising gut health issues have increased demand for gastroenterology medicines and gut health products.

Bloating, dyspepsia, and acid reflux are some of the most common gut issues.

Commonly used gastroenterology medicines include-

  • Antacids
  • H2 blockers
  • Proton pump inhibitors
  • Prokinetic drugs

India’s gastroenterology market landscape includes large pharmaceutical giants and manufacturers.

The Leading Gastroenterology Medicine Manufacturers in India-

Sun Pharmaceutical Industries Ltd –

It is recognized as India’s top pharmaceutical company.

Sun Pharma has a well-established portfolio in gastroenterology.

Pantocid (pantoprazole) by Sun Pharma is a commonly used proton pump inhibitor.

Cipla Ltd –

It is known for its generic drug manufacturing.

Cipla manufactures a wide array of medicines in gastroenterology, including-

  • Antacids and antiulcer drugs
  • Anti-infectives and antidiarrheals

Mankind Pharma Ltd

It is one of India’s leading pharmaceutical companies manufacturing gastroenterology drugs.

Its gastroenterology portfolio includes PPIs and antiemetics.

  • Pantakind (Pantoprazole)
  • Vomikind (Ondansetron)

Aprazer Healthcare –

 Aprazer Healthcare is a pharmaceutical manufacturer with a specialty drug portfolio.

It manufactures a wide array of drugs in the gastroenterology segment-

  • Proton pump inhibitors
  • Gastroselective antibiotics

Since its inception, Aprazer Healthcare has emerged as a trusted gastroenterology drug manufacturer and exporter.

Torrent Pharmaceuticals Ltd.

Torrent Pharma emphasizes manufacturing prescription drugs.

Its flagship gastroenterology medicines include-

Nexpro (esomeprazole)

Domstal (domperidone)

Aprazer Healthcare – Gastroenterology Medicine Supplier in India

Aprazer Healthcare specializes in manufacturing gastroenterology medicines.

Our core areas in GIT care include routine acid suppressants and hepatobiliary care.

Our key products include-

  • Udikast – Ursodeoxycholic Acid (UDCA)
  • Aprapan – Pantoprazole
  • Rifaxigem 400 – Rifaximin 400mg

Our manufacturing facilities are compliant with regulatory standards.

Equipped with advanced technology, we manufacture affordable and quality drugs.

Our stringent quality parameters ensure each product is within limits.

Aprazer Healthcare – A Chosen CDMO Partner for Gastroenterology Medicines

We offer contract manufacturing services at our well-established plant in Haridwar, Uttarakhand.

We have world–class infrastructure leveraging automated systems.

We utilize advanced technology to minimize the risk of cross-contamination.

  • Dedicated blocks and production pipelines
  • Dedicated Air handling unit (AHU)
  • Heating, ventilation, and air-conditioning (HVAC) system

Our key attributes include –

  • Regulatory compliance
  • Quality assurance and quality control
  • Robust supply chain

Committed to manufacturing quality drugs, we are focused on building long-term customer relationships.

Indian Pharmaceutical Manufacturer/Exporter to Nigeria

Often called the most populous country and a “Giant of Africa”, Nigeria imports a large volume of generics from India.

Among the trusted pharmaceutical companies from India, Aprazer Healthcare is a recognized drug manufacturer and exporter.

Exporting products to Africa for years, we have a deep understanding of documentation and logistics.

From general medicines to essential medicines, we manufacture drugs for every healthcare need.

Equipped with modern infrastructure, we are at the forefront of manufacturing advanced drugs.

Choose Aprazer Healthcare for pharmaceutical exports in Nigeria:

We are a GMP & GLP certified company.

Our product portfolio expands across all therapeutic segments.

  • Oncology
  • Gastroenterology
  • Hepatology

Why are we different from other manufacturers?

Besides regulatory-compliant manufacturing, our in–house quality control parameters ensure every product is within defined limits.

  • Global standard manufacturing
  • Robust supply chain
  • Timely and consistent delivery
  • Extensive product catalogue
  • Flexible manufacturing capacities.

Manufacturing excellence/expertise:

Adhering to regulatory standards, our manufacturing facilities are –

  • Equipped with modern technology
  • Separate manufacturing blocks
  • Robust research and drug development
  • AHU and HVAC systems

Robust quality controls –

We follow a stringent quality control framework.

From sourcing the raw material to the manufacturing of finished products, we ensure quality standards.

  • Pharmaceutical-grade raw material
  • Finished products quality testing
  • In-process manufacturing standards

Contract drug manufacturing services for Nigerian brands –

Offering third-party manufacturing services, we are always the choice of stakeholders.

  • Tailored formulations
  • customized packaging
  • Bulk manufacturing

Complete document support –

  • Import-Export Code
  • Drug license
  • Manufacturing license
  • WHO-GMP certificate
  • Certificate of pharmaceutical products
  • Certificate of analysis
  • CDSCO documents
  • Financial documents
  • Logistics documentation

Our regulatory expertise and services –

Our team of experts has a deep understanding of the regulatory framework.

We offer comprehensive support for –

  • Product approvals
  • Country-specific dossier
  • Marketing licenses

Partner with Aprazer Healthcare to bring quality healthcare from India to Nigeria.

  • Flexible MOQ
  • Wide product range
  • Transparent communication

If you are looking for a trusted pharmaceutical manufacturer and exporter for Nigeria, connect with our team.

Pharmaceutical Exporter & Supplier from India to Ghana

Among the Indian pharmaceutical manufacturers, Aprazer Healthcare is a trusted global pharmaceutical company.

As a medicine manufacturer, we target international markets in Ghana and West Africa.

We manufacture a wide range of generic and branded drugs to meet Ghanaian pharmaceutical demand.

India accounts for 70-80 % of Ghana’s total pharmaceutical imports.

The pharmaceutical exports from India include tablets, capsules, and injectables.

Looking for specialty medicines in Ghana?

Aprazer Healthcare is the first choice for global pharmaceutical supplies.

Enforcing strict quality controls & regulatory standards, we are a globally accepted brand.

We offer a comprehensive range of specialty care drugs, providing –

Committed to quality, compliance, and customer satisfaction, we offer numerous advantages for our export clients.

  • Competitive pricing
  • Widest product catalogue
  • End-to-end regulatory support
  • Efficient logistics management
  • Consistent supply chain
  • Uninterrupted medicine availability

Through our flexible Minimum Order Quantities (MOQ) and strategic partnerships, we support both small and large-scale drug requirements.

High–demand product segments in Ghana –

Antibiotics and anti-infectives – Given the region’s high burden of endemic and infectious diseases, antibiotics and anti-infectives have always remained in demand.

Cardiovascular, diabetes, and oncology drugs – Due to rapid urbanization, lifestyle shifts, and the emergence of chronic diseases, the requirement for life-saving drugs has increased manifold.

Generic drugs – Approximately, 40 percent of healthcare costs in Ghana are paid out of pocket, making affordable drugs a necessity.

Patients and healthcare agencies strongly rely on generic options.

Why is Aprazer Healthcare a trusted pharmaceutical exporter to Ghana?

By supplying trusted, quality products to Ghana, we aim to strengthen the Ghanaian healthcare system.

Adhering to GMP & GLP standards of manufacturing, each of our products is qualified and certified.

We offer complete regulatory support for the export of drugs to Ghana.

  • Complete export documentation
  • Tamper-evident export packaging
  • Transparent logistics support

Expand your pharmaceutical business in Ghana with Aprazer Healthcare –

We are also a third-party drug manufacturer offering custom packaging, branding, and GMP compliant manufacturing.

We specialize in manufacturing oral solid dosage forms.

Our state-of-the-art manufacturing is equipped with the latest advanced technology.

  • Automated systems
  • Robust environmental controls
  • Dedicated manufacturing blocks
  • Continuous research and drug development

Why choose us?

We are the fastest–growing pharmaceutical company expanding globally.

  • Worldwide reach
  • Widest portfolio
  • Affordable medicines
  • Quality control and assurance
  • Advanced supply chain
  • Innovative formulations

We believe in building long–term relationships through our dedicated and transparent services.

Pharmaceutical Manufacturer and Exporter to Saudi Arabia From India

India accounts for a large share of pharmaceutical imports in Saudi Arabia.

Saudi Arabia comprises the largest pharmaceutical market connecting the Gulf and the Middle East.

Saudi Arabia fulfill its 80 % of pharmaceutical demand through imports.

Exporting pharmaceuticals worth USD 138 million to USD 209 million annually to Saudi Arabia, India is a prominent drug supplier to Saudi Arabia.

Indian medicines comply with global regulatory standards and are highly demanded and acceptable in global markets.

Aprazer Healthcare is a generic drug manufacturer from India.

We export drugs to 20+ countries in the Middle East and the Gulf.

Meeting the strict standards of WHO-GMP manufacturing, Aprazer Healthcare is a globally trusted brand.

Aprazer Healthcare as a drug manufacturer:

With a mission to provide affordable medicines worldwide, we aim to contribute to the economic welfare of the people as well as the government.

Our manufacturing standards constitute GMP manufacturing along with stringent in-house quality control parameters.

Implementing the latest technology, we manufacture affordable drugs without any compromise on quality.

Our medicines are trusted by doctors and pharmacies.

Our history of zero regulatory audit failures has built our reputation as a reliable pharmaceutical manufacturer.

Why is Aprazer Healthcare a chosen pharmaceutical exporter from India to Saudi Arabia?

Aprazer Healthcare is trusted for its transparent dealings and consistent supplies.

With a decade of expertise in pharmaceutical drug manufacturing and export, we clearly understand our partner’s goal.

We invest heavily in market –focused solutions to compete in the crowded regulatory landscape.

Strategic B2B Flexibility-

Offering Flexible MOQ, we allow our partner to secure high-value generics scaling with market demand.

This reduces excessive upfront capital investments.

Regulatory compliance for Saudi Arabia –

Our team of experts provides end-to-end support from documentation to licensing of products in Saudi markets.

  • Hassle-free regulatory submissions/import permits
  • Complete documents
  • CTD/eCTD dossiers

Global standard manufacturing–

Our manufacturing units are accredited by the global health authorities.

We are WHO-GMP/ISO and EU-GMP certified manufacturers.

Advanced Logistics –

Our logistics support offers temperature-controlled shipments.

We practice strict controls for temperature and humidity fluctuations.

Extensive portfolio-

We offer a global range of pharmaceuticals in all therapeutic segments.

  • Anticancer drugs
  • Antivirals
  • Antibiotics

Contract manufacturing-

We are a recognized contract manufacturer from India.

Get your formulation transformed into real solutions, with our custom scaling and quality manufacturing.

Partner with Aprazer Healthcare to drive excellence from India to Saudi Arabia

Abdominal Cramp Relief Medicines: Antispasmodic Combinations

These are used to relieve smooth muscle cramps and spasms.Antispasmodic agents are combined with-

Painkillers/muscle relaxant and anxiolytic agents

These are widely used to relax muscles in the gut.

These are significantly used to relieve muscle spasms caused in the GIT, bladder, or the gallbladder.

What are the commonly used Antispasmodic combinations?

  • Antispasmodic + Analgesic medicine – 

These relax the muscles and reduce spasm.

The painkiller reduces the pain.

It is widely used for abdominal spasm and pain.

Drotaverinee + Paracetamol

Drotaverinee + Mefenamic Acid

  • Antispasmodic + Anxiolytic combination – 

It is a combination of an anticholinergic with an anti-anxiety or tranquilizing agent.

It lowers the aggravated spasms caused by anxiety.

  • Clidinium + Chlordiazepoxide
  • Isopropamide + Trifluoperazine

What are the antispasmodic drug uses? 

These are widely used to relieve muscle spasm and pain during –

  • IBS
  • Menstrual pain
  • Abdominal colic
  • Biliary and renal colic

Antispasmodic drug working – 

The antispasmodic drugs work by inhibiting abnormal muscle contractions.

  • Anti-muscarinic drugs – They block the cholinergic receptors.

This reduces the excessive muscular contraction.

  • Dicyclomine
  • Hyoscine butylbromide
  • smooth muscle relaxants – These relax the smooth muscles in the gut and the bladder.

They relieve pain and muscle contractions.

  • Drotaverine
  • Mebeverine
  • Calcium channel blockers – These inhibit the calcium channel, causing muscular contraction.
  • Pinaverium bromide
  • Otilonium bromide

What are the antispasmodic drug side effects?

The common side effects include-

  • Dry mouth
  • Constipation
  • Dizziness
  • Lightheadedness
  • Drowsiness
  • Weakness
  • Blurred vision
  • Decreased sweating

How do antispasmodic drugs differ from antispastic drugs?

Antispasmodic drugs relax smooth muscles.

It helps relieve smooth muscle contractions.

These are mainly used to control involuntary muscle spasm.

Antispastic drugs are used to relax skeletal muscles.

They are used to relieve back pain.

Aprazer Healthcare – A recognized global drug exporter/ supplier.

Aprazer Healthcare is a pharmaceutical drug manufacturing company.

We are a leading contract  drug manufacturer from India.

Manufacturing a global range of antispasmodic combinations, Aprazer Healthcare is an antispasmodic drug exporter.

Leveraging our expertise in manufacturing innovative drug therapies, we manufacture the latest advanced drug combinations.

We are trusted for global exports-

  • WHO-GMP compliant manufacturing
  • Robust distribution network
  • Regulatory expertise
  • Quality control and quality assurance
  • Transparent communication

The Next Pandemic Risk? How Changing Global Weather is Driving the Rise in Malaria Cases

Global malaria cases rose to 282 million in 2025, representing about a 9 million increase in cases.The global rise in temperature and high rainfall increase the breeding ground for the mosquitoes.

The reasons for rising malaria – 

Global warming – 

The rising temperature in the cold temperate regions offers favorable space for propagation.

Drift into new latitudes – 

The changes in the season.

Warmer winters and the extended summers cause a shift in mosquito breeding, spreading into new areas.

New invasive species– the stagnant waters and urban water tanks, pollution, etc. introduce genetic variation, emerging new invasive species.

The increased use of pesticides/chemicals – This increases drug resistance.

The malarial parasite develops genetic changes and more resistant variants.

What are the malaria symptoms?

  • Fever and chills
  • Body ache sand joint pain
  • Nausea, vomiting
  • Systemic fatigue

Serious symptoms – 

If malaria is left untreated.

It can lead to severe organ failure and even death.

  • Altered consciousness
  • Difficulty in breathing
  • Severe anemia
  • Jaundice
  • Acute organ failure
  • Dark urine
  • Low blood sugars

The cause of Malaria –

It is caused by the bite of an infected mosquito (female Anopheles).

How is malaria transferred?

The mosquito carries the parasite.

By biting another healthy person, it transfers into the other person.

Malaria is also transmitted by blood-to-blood contact.

Sharing needles or infected blood.

How to prevent malaria?

Avoid mosquito bites and breeding grounds.

  • Use insect repellants
  • Sleep under bed nets
  • Cover the skin
  • Avoid outdoor movements in the evening
  • Clear standing waters
  • Use sprays

Can malaria spread from a pregnant mother to the child?

It is a very rare condition for malaria to get directly transmitted.

However, malaria may cause several birth defects.

  • Still birth
  • Miscarriage
  • Premature delivery
  • low birth rate

What are anti-malarial medicines?

The malaria drug therapy depends upon the type of causative species.

  • Artemisinin-based Combination Therapies (ACTs)

These are used to treat uncomplicated malaria.

The fast-acting artemisinic drug is combined with a slow-acting drug.

It efficiently clears the parasite and prevents drug resistance.

  • Artemether-lumefantrine
  • Artesunate-mefloquine
  • Chloroquine Phosphate- It is used for non-falciparum species 
  1. Atovaquone-proguanil – These are widely used to prevent relapse.

It eliminates the dormant malarial parasites, hidden in the liver.

The leading pharmaceutical manufacturer for antimalarial drugs 

Aprazer Healthcare is a leading contract drug manufacturer.

As a leading drug exporter, we export a wide range of anti-malarial drugs.

To combat the malarial crises /pandemic, we are committed to manufacturing affordable anti- malarial drugs.

  • Large-scale manufacturing unit
  •  Adherence to global health standards
  • Regulatory-compliant drugs

We have a strong distribution network, supplying drugs worldwide.

Our flagship products include –

  • Artemether + Lumefantrine
  • Hydroxychloroquine Sulphate
  • Mefloquine 250mg
  • Quinine 300mg

Collaborating with the global health centers and public health sectors, we are committed to providing equitable access to all.

Diabetic Neuropathy Treatment and the Drugs

Diabetic neuropathy is a condition that occurs in people with chronic diabetes.

It is nerve damage because of high sugar levels.

Nerve damage can occur in the legs, hands, and internal organs.

Why does high blood sugar damage the nerves?

The high levels of circulating sugars clog the thin blood vessels.

This blocks the supply of blood to the nerves.

  • It inhibits the oxygen supply to the nerves.
  • It leads to oxidative stress.
  • Sorbitol buildup causes fluid accumulation inside the nerve cells.
  • Breaks down the myelin sheath.
  • Interrupts nerve conduction

The types of Diabetic Neuropathy – 

Peripheral nerve damage – The nerves of the hands, arms, and legs get damaged.

Autonomic Neuropathy- The nerves of the internal organs get damaged.

It can be the nerves of the digestive system, urinary bladder, and heart.

Proximal Neuropathy- It is nerve damage in the hip, buttock, thighs, or legs.

It occurs as severe pain and muscle weakness.

Focal Neuropathy- 

A specific nerve gets damaged.

What are the symptoms of diabetes damaging the nerves?

Peripheral nerve damage- 

Nerve damage in the peripheral organs.

Hands and legs

  • Tingling pain
  • Needle-like feeling.
  • Burning, sharp pain
  • Numbness
  • Poor balance
  • Muscle weakness

Autonomic nerve damage – 

The nerve damage affects internal organs –

Like the stomach, heart, and bladder.

  • Stomach upset
  • Diarrhea /constipation
  • Inconsistent urination
  • Hypotension
  • Sexual problems
  • Unusual Sweating or no sweating.

Which pain-relieving medicines are used to treat diabetic neuropathy?

These are widely used to relieve neuropathy pain.

  • Anticonvulsants – 

These calm the nervous system.

It reduces the sharp pain.

  • Antidepressants – It lowers the spinal cord or brain signals.
  1. Topical anesthetics- These are local anesthetics.

These are used for local pain relief.

How to manage diabetic nerve damage?

The various steps to manage nerve damage.

  • Keep blood sugar within range.
  • Avoiding injuries
  • Using pain-relief medicines
  • Practice hygiene and foot care
  • Limit alcohol /smoking
  • Low-impact exercises

Why are NSAIDs ineffective in neuropathic pain?

NSAIDs have limited use in managing diabetes induced pain.

They target inflammation.

They cannot relieve pain caused by changes in nerve signals.

It also increases the risk of toxicity.

  • Kidney damage
  • High blood pressure
  • Fluid retention
  • Stomach irritation /ulcers

Which is the leading contract drug  manufacturer of Neurology Drugs?

Aprazer Healthcare is the top pharmaceutical company.

We manufacture a global range of pharmaceutical products.

We are the leading drug exporters worldwide.

We export neurology drugs to Asia, Africa, and America.

Our neurology product portfolio consists of –

  • Anticonvulsants
  • Neuroprotective combinations
  • Venotonic medicines